| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.233685 |
| B2M | beta-2-microglobulin | 0.12476 |
| NDRG1 | N-myc downstream regulated 1 | 0.121787 |
| EGR1 | early growth response 1 | 0.103406 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0976379 |
| INHBA | inhibin, beta A | 0.0961655 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0935034 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.089167 |
| HLA-A | major histocompatibility complex, class I, A | 0.0837684 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0791006 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0749518 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0702324 |
| FTL | ferritin, light polypeptide | 0.0675653 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.062881 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0615689 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0592812 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0585562 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.058313 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0555021 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0512739 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0471753 |
| HLA-B | major histocompatibility complex, class I, B | 0.0453119 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0438836 |
| LOXL2 | lysyl oxidase-like 2 | 0.0436872 |
| CD109 | CD109 molecule | 0.0429155 |
| HDAC9 | histone deacetylase 9 | 0.0421088 |
| FMNL2 | formin-like 2 | 0.0415616 |
| JUN | jun proto-oncogene | 0.0413946 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0410086 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0403301 |
| ANGPTL4 | angiopoietin-like 4 | 0.039891 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0382118 |
| EML5 | echinoderm microtubule associated protein like 5 | 0.037808 |
| CADM1 | cell adhesion molecule 1 | 0.0372947 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0370207 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0364473 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0357722 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0335758 |
| TPI1 | triosephosphate isomerase 1 | 0.0333834 |
| CCNL1 | cyclin L1 | 0.033293 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0321339 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0311584 |
| IER2 | immediate early response 2 | 0.0308003 |
| MMP12 | matrix metallopeptidase 12 | 0.0307567 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0306115 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0303593 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0296852 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0290828 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0281201 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0280354 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0269851 |
| ADM | adrenomedullin | 0.0267797 |
| MTSS1 | metastasis suppressor 1 | 0.0267135 |
| SP100 | SP100 nuclear antigen | 0.0262957 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0259864 |
| CDH13 | cadherin 13 | 0.025774 |
| IFI44L | interferon-induced protein 44-like | 0.0255143 |
| COL5A1 | collagen, type V, alpha 1 | 0.0253121 |
| RACK1 | receptor for activated C kinase 1 | 0.0253063 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.025246 |
| ZFP36 | ZFP36 ring finger protein | 0.0251244 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.024698 |
| INTS6 | integrator complex subunit 6 | 0.0246393 |
| TMSB10 | thymosin beta 10 | 0.0243937 |
| MMP2 | matrix metallopeptidase 2 | 0.0238967 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0234386 |
| SQSTM1 | sequestosome 1 | 0.0232661 |
| RPL23 | ribosomal protein L23 | 0.0232048 |
| TPM3 | tropomyosin 3 | 0.023064 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0230259 |
| RND3 | Rho family GTPase 3 | 0.0222575 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.022169 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0221682 |
| GCNA | germ cell nuclear acidic peptidase | 0.0221341 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0218354 |
| ARRDC3 | arrestin domain containing 3 | 0.0217372 |
| LOX | lysyl oxidase | 0.0217018 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0215796 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0213906 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0213202 |
| RPS12 | ribosomal protein S12 | 0.0212033 |
| PDE10A | phosphodiesterase 10A | 0.0209871 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0208442 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.020829 |
| RPS17 | ribosomal protein S17 | 0.020767 |
| C1R | complement component 1, r subcomponent | 0.0207191 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0205134 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0202649 |
| PLIN2 | perilipin 2 | 0.0199318 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0198984 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0198518 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0194841 |
| COL5A3 | collagen, type V, alpha 3 | 0.0194707 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0193191 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0192335 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0190758 |
| ECE1 | endothelin converting enzyme 1 | 0.0188855 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0186926 |
| ATF3 | activating transcription factor 3 | 0.018508 |
| IL6 | interleukin 6 | 0.0184448 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21876 |
| MT2A | metallothionein 2A | -0.187791 |
| VIM | vimentin | -0.158281 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.146997 |
| FN1 | fibronectin 1 | -0.119135 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0924871 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0798298 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0723838 |
| CENPF | centromere protein F, 350/400kDa | -0.0627036 |
| CD44 | CD44 molecule (Indian blood group) | -0.0595228 |
| FRMD4A | FERM domain containing 4A | -0.0563691 |
| AFAP1 | actin filament associated protein 1 | -0.0547086 |
| MKI67 | marker of proliferation Ki-67 | -0.0522253 |
| PTMA | prothymosin, alpha | -0.0517021 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0510134 |
| ANLN | anillin, actin binding protein | -0.0467645 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0464593 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0463735 |
| PGK1 | phosphoglycerate kinase 1 | -0.0462641 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0431098 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0422372 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0399414 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0398188 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0385145 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0381953 |
| HMGB2 | high mobility group box 2 | -0.0379514 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0378332 |
| TPX2 | TPX2, microtubule-associated | -0.0368661 |
| ZNF292 | zinc finger protein 292 | -0.0365147 |
| NRP1 | neuropilin 1 | -0.0364953 |
| RPLP1 | ribosomal protein, large, P1 | -0.0361527 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0357389 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.034795 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0343887 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0340374 |
| XPO1 | exportin 1 | -0.0339835 |
| CANX | calnexin | -0.0337668 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0336823 |
| NF1 | neurofibromin 1 | -0.0332228 |
| MAP4 | microtubule-associated protein 4 | -0.0327061 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0317164 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0315424 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0309618 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0309441 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0304878 |
| ANXA2 | annexin A2 | -0.0304802 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0303031 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0299495 |
| RPLP2 | ribosomal protein, large, P2 | -0.029854 |
| CDK19 | cyclin-dependent kinase 19 | -0.0293155 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0286138 |
| GLG1 | golgi glycoprotein 1 | -0.0285316 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.028128 |
| JMJD1C | jumonji domain containing 1C | -0.0279809 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0275824 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0269439 |
| RPS13 | ribosomal protein S13 | -0.0265963 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0262929 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0259752 |
| RPS21 | ribosomal protein S21 | -0.0258375 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0257258 |
| RRBP1 | ribosome binding protein 1 | -0.0257258 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0256569 |
| TPM4 | tropomyosin 4 | -0.0256235 |
| TCF12 | transcription factor 12 | -0.0256219 |
| NBEAL1 | neurobeachin-like 1 | -0.0254663 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0254436 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0252508 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.025044 |
| CENPE | centromere protein E, 312kDa | -0.0249248 |
| ACTN4 | actinin, alpha 4 | -0.0248367 |
| CALR | calreticulin | -0.0246982 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0244465 |
| ASPH | aspartate beta-hydroxylase | -0.0241886 |
| H1-0 | H1.0 linker histone | -0.0239865 |
| HDLBP | high density lipoprotein binding protein | -0.0239125 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0238515 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0234139 |
| LMNA | lamin A/C | -0.0234087 |
| RPL19 | ribosomal protein L19 | -0.0233034 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0232967 |
| SEC24D | SEC24 family member D | -0.0232806 |
| RPS6 | ribosomal protein S6 | -0.0232653 |
| CDC27 | cell division cycle 27 | -0.0232491 |
| NBAS | neuroblastoma amplified sequence | -0.0231544 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.02314 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0231362 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0230953 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0230467 |
| KIF4A | kinesin family member 4A | -0.0229229 |
| ITGAV | integrin, alpha V | -0.0228498 |
| NKTR | natural killer cell triggering receptor | -0.0225111 |
| OGA | O-GlcNAcase | -0.0224734 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0222494 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0221815 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0221286 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.022062 |
| RLF | rearranged L-myc fusion | -0.0219058 |
| GOLGA4 | golgin A4 | -0.0218735 |
| MORF4L1 | mortality factor 4 like 1 | -0.0218684 |
