| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.120411 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.107751 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.100835 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0832309 |
| RPL23 | ribosomal protein L23 | 0.0820425 |
| MT2A | metallothionein 2A | 0.0722701 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0712019 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0701342 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0693112 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0624304 |
| VEGFA | vascular endothelial growth factor A | 0.061124 |
| RPS12 | ribosomal protein S12 | 0.0608798 |
| HDAC9 | histone deacetylase 9 | 0.0600479 |
| NDRG1 | N-myc downstream regulated 1 | 0.05885 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0582223 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0527268 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0511193 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.047533 |
| NAV2 | neuron navigator 2 | 0.0465074 |
| RPS6 | ribosomal protein S6 | 0.0459102 |
| INTS6 | integrator complex subunit 6 | 0.043831 |
| HLA-A | major histocompatibility complex, class I, A | 0.043269 |
| VIM | vimentin | 0.0431408 |
| B2M | beta-2-microglobulin | 0.0424886 |
| RPS8 | ribosomal protein S8 | 0.0414663 |
| RND3 | Rho family GTPase 3 | 0.0412586 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.039568 |
| RPL3 | ribosomal protein L3 | 0.037615 |
| RACK1 | receptor for activated C kinase 1 | 0.0355985 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0350344 |
| RPS3 | ribosomal protein S3 | 0.0333766 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0324036 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0322097 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0314022 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.029296 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0287318 |
| PLIN2 | perilipin 2 | 0.028717 |
| SFTPA2 | surfactant protein A2 | 0.0284258 |
| RPL11 | ribosomal protein L11 | 0.0274997 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0273583 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0268397 |
| PCBP2 | poly(rC) binding protein 2 | 0.025742 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0251907 |
| ADM | adrenomedullin | 0.0244812 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0242458 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0241991 |
| RPS4X | ribosomal protein S4, X-linked | 0.0241648 |
| PGM3 | phosphoglucomutase 3 | 0.0241394 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0237077 |
| RPL26 | ribosomal protein L26 | 0.023608 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0229221 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0226662 |
| GDF15 | growth differentiation factor 15 | 0.022401 |
| STC1 | stanniocalcin 1 | 0.0223528 |
| RPL37A | ribosomal protein L37a | 0.0220545 |
| PKM | pyruvate kinase, muscle | 0.02198 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.021735 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0215149 |
| FNIP1 | folliculin interacting protein 1 | 0.0212064 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0210184 |
| RPL7 | ribosomal protein L7 | 0.0209104 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0208278 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0206098 |
| RPL5 | ribosomal protein L5 | 0.0205782 |
| GOLGA4 | golgin A4 | 0.020226 |
| RPS17 | ribosomal protein S17 | 0.020082 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0198875 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0194048 |
| RPL31 | ribosomal protein L31 | 0.0193811 |
| RPL37 | ribosomal protein L37 | 0.0192102 |
| OPTN | optineurin | 0.0191952 |
| RPL9 | ribosomal protein L9 | 0.0188153 |
| GOLGB1 | golgin B1 | 0.01874 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0186717 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0186597 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0186394 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0186255 |
| RPLP1 | ribosomal protein, large, P1 | 0.0182483 |
| RPS2 | ribosomal protein S2 | 0.0181532 |
| FTL | ferritin, light polypeptide | 0.0181182 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.018001 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.017641 |
| FAM219A | family with sequence similarity 219, member A | 0.0173138 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0173091 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.017004 |
| RPL21 | ribosomal protein L21 | 0.0168837 |
| RPS27 | ribosomal protein S27 | 0.0168772 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0167691 |
| BRD2 | bromodomain containing 2 | 0.0165676 |
| RPS19 | ribosomal protein S19 | 0.0165198 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0164653 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0163594 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0163541 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0163347 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0160307 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.015806 |
| RPL35A | ribosomal protein L35a | 0.0157918 |
| TPM3 | tropomyosin 3 | 0.0157296 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0156966 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0155998 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.18803 |
| GLIS3 | GLIS family zinc finger 3 | -0.14101 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.137474 |
| FN1 | fibronectin 1 | -0.135497 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.116214 |
| BICC1 | BicC family RNA binding protein 1 | -0.116119 |
| EXT1 | exostosin glycosyltransferase 1 | -0.113185 |
| VCAN | versican | -0.0740559 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0717348 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0682082 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0647287 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0632317 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0618491 |
| DST | dystonin | -0.0574247 |
| VCL | vinculin | -0.0565022 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0557533 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0555954 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0532635 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0511893 |
| ANXA2 | annexin A2 | -0.0495311 |
| THBS1 | thrombospondin 1 | -0.0491361 |
| PGK1 | phosphoglycerate kinase 1 | -0.0488845 |
| RTN4 | reticulon 4 | -0.0481956 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0479168 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0476684 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0465214 |
| COL1A1 | collagen, type I, alpha 1 | -0.0459414 |
| TENM2 | teneurin transmembrane protein 2 | -0.0448229 |
| IER3 | immediate early response 3 | -0.0445181 |
| SMAD3 | SMAD family member 3 | -0.0442642 |
| RAI14 | retinoic acid induced 14 | -0.0440511 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0429763 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0416596 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0410857 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0404218 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0400914 |
| PDE10A | phosphodiesterase 10A | -0.0384369 |
| JMJD1C | jumonji domain containing 1C | -0.0376384 |
| SBF2 | SET binding factor 2 | -0.0373164 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0359539 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0355739 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0347183 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0336333 |
| CD44 | CD44 molecule (Indian blood group) | -0.0334473 |
| TPM4 | tropomyosin 4 | -0.0331745 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0331157 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0326248 |
| OGA | O-GlcNAcase | -0.0320696 |
| QKI | QKI, KH domain containing, RNA binding | -0.0308942 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0303656 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0303375 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0301053 |
| RUNX2 | runt-related transcription factor 2 | -0.0299078 |
| EHBP1 | EH domain binding protein 1 | -0.0297618 |
| CD2AP | CD2-associated protein | -0.0296667 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0295549 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.028724 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0286962 |
| TPM1 | tropomyosin 1 (alpha) | -0.0283168 |
| RBM39 | RNA binding motif protein 39 | -0.0281958 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.028107 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0279105 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0278487 |
| COL1A2 | collagen, type I, alpha 2 | -0.0278081 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.027592 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.027388 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0268262 |
| NF1 | neurofibromin 1 | -0.026725 |
| TXNRD1 | thioredoxin reductase 1 | -0.0265157 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0264903 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0264306 |
| FRMD5 | FERM domain containing 5 | -0.0263669 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0262371 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.02617 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0261134 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0257202 |
| ZNF292 | zinc finger protein 292 | -0.0253439 |
| AFDN | afadin, adherens junction formation factor | -0.0248385 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0245993 |
| THOC2 | THO complex 2 | -0.0244898 |
| NAV1 | neuron navigator 1 | -0.024063 |
| RNF213 | ring finger protein 213 | -0.023985 |
| PHF21A | PHD finger protein 21A | -0.0239727 |
| ATXN1 | ataxin 1 | -0.0234606 |
| TNS3 | tensin 3 | -0.0234441 |
| THBS2 | thrombospondin 2 | -0.0234249 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0232846 |
| LRRC7 | leucine rich repeat containing 7 | -0.0231277 |
| ATP13A3 | ATPase type 13A3 | -0.0230859 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0230377 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0230037 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0228274 |
| TNNC1 | troponin C type 1 (slow) | -0.0223484 |
| RASAL2 | RAS protein activator like 2 | -0.0222806 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0222186 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0219306 |
| DIAPH2 | diaphanous-related formin 2 | -0.0216768 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0214743 |
| BBX | bobby sox homolog (Drosophila) | -0.0212043 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0211553 |
