| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | 0.101675 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0803449 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0746045 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0734614 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0733318 |
| FMNL2 | formin-like 2 | 0.0688129 |
| LDHA | lactate dehydrogenase A | 0.0681675 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.061637 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0610144 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0607872 |
| TPI1 | triosephosphate isomerase 1 | 0.0571161 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0489779 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0475471 |
| GPC6 | glypican 6 | 0.0473495 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0467332 |
| CD44 | CD44 molecule (Indian blood group) | 0.0459692 |
| RPS12 | ribosomal protein S12 | 0.0456835 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0456639 |
| ENO1 | enolase 1, (alpha) | 0.0432402 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0406772 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0402226 |
| RBM25 | RNA binding motif protein 25 | 0.038002 |
| GSK3B | glycogen synthase kinase 3 beta | 0.037723 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0376899 |
| CLTC | clathrin, heavy chain (Hc) | 0.0365468 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0359411 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0344264 |
| CALR | calreticulin | 0.0342375 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0340157 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0337935 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0337355 |
| RSF1 | remodeling and spacing factor 1 | 0.0334976 |
| BBX | bobby sox homolog (Drosophila) | 0.0333527 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0328354 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.032522 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0306129 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0305911 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0304489 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0302592 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0299943 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0299718 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.029688 |
| VIM | vimentin | 0.0296279 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0295432 |
| FLNB | filamin B, beta | 0.0294579 |
| SBF2 | SET binding factor 2 | 0.0290952 |
| KIAA1958 | KIAA1958 | 0.0290229 |
| PHF21A | PHD finger protein 21A | 0.0286451 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0284644 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0282955 |
| PGK1 | phosphoglycerate kinase 1 | 0.0281113 |
| KIAA1328 | KIAA1328 | 0.0280983 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0274665 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0273622 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0269013 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0267862 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0266921 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0264435 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0264257 |
| OSMR | oncostatin M receptor | 0.0261159 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.026079 |
| DTNA | dystrobrevin, alpha | 0.0259123 |
| THOC2 | THO complex 2 | 0.0258122 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0257965 |
| MAP1B | microtubule-associated protein 1B | 0.0257328 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0256681 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0256657 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0255317 |
| RPL11 | ribosomal protein L11 | 0.0254768 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0252489 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0252231 |
| RASAL2 | RAS protein activator like 2 | 0.0251917 |
| RECQL | RecQ helicase-like | 0.0249533 |
| ACER3 | alkaline ceramidase 3 | 0.0248924 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0247681 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0246187 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0245729 |
| RORA | RAR-related orphan receptor A | 0.024367 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0240371 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0238836 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0238621 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0238538 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0238008 |
| RPL9 | ribosomal protein L9 | 0.0237056 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0234153 |
| INSR | insulin receptor | 0.0234051 |
| B2M | beta-2-microglobulin | 0.0232553 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0231097 |
| CPNE3 | copine III | 0.0228747 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0227731 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0227566 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0227301 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0226865 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0226672 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0224769 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0224432 |
| NDRG1 | N-myc downstream regulated 1 | 0.0223426 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0223292 |
| EP400 | E1A binding protein p400 | 0.0223013 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0222768 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0954347 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0800932 |
| RIGI | RNA sensor RIG-I | -0.0672291 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0549226 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0536151 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0519472 |
| RPLP1 | ribosomal protein, large, P1 | -0.0517279 |
| GOLGA4 | golgin A4 | -0.0477863 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0452297 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0442481 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0436017 |
| RPS8 | ribosomal protein S8 | -0.0425381 |
| S100A10 | S100 calcium binding protein A10 | -0.0421357 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0419966 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0397389 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0391142 |
| GNAS | GNAS complex locus | -0.0374273 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0370765 |
| SDC4 | syndecan 4 | -0.0366958 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.036152 |
| NGLY1 | N-glycanase 1 | -0.0356225 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0354118 |
| RPL35A | ribosomal protein L35a | -0.0341386 |
| SNX14 | sorting nexin 14 | -0.0340019 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0333971 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0333204 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.032423 |
| ZNF638 | zinc finger protein 638 | -0.0311841 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0310509 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0310294 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0308701 |
| SRPK2 | SRSF protein kinase 2 | -0.0308587 |
| TLK1 | tousled-like kinase 1 | -0.0299921 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0297708 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0295971 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0286451 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0285817 |
| USP53 | ubiquitin specific peptidase 53 | -0.0285376 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0284651 |
| GLRX | glutaredoxin (thioltransferase) | -0.0282253 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0280345 |
| IL6ST | interleukin 6 signal transducer | -0.02794 |
| SAFB | scaffold attachment factor B | -0.0278475 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0275165 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0275048 |
| H3-3B | H3.3 histone B | -0.0274375 |
| GOLGA3 | golgin A3 | -0.0271281 |
| RCOR1 | REST corepressor 1 | -0.0270459 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0269409 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0268855 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0268718 |
| NUMB | numb homolog (Drosophila) | -0.0266421 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0266134 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.026374 |
| RPL31 | ribosomal protein L31 | -0.0263455 |
| SP100 | SP100 nuclear antigen | -0.0260983 |
| MED13 | mediator complex subunit 13 | -0.0260877 |
| LMO7 | LIM domain 7 | -0.0260001 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0257222 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0253773 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0253554 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0253133 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0252767 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0249492 |
| DEK | DEK proto-oncogene | -0.0249037 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | -0.0249035 |
| RPS28 | ribosomal protein S28 | -0.0248928 |
| EP300 | E1A binding protein p300 | -0.0248264 |
| BRD4 | bromodomain containing 4 | -0.0247198 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.02451 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0245021 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0241959 |
| RPS6 | ribosomal protein S6 | -0.0240737 |
| NUP58 | nucleoporin 58 | -0.0240316 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0240265 |
| RPL34 | ribosomal protein L34 | -0.0239884 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0239761 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0239425 |
| RPL27A | ribosomal protein L27a | -0.0238631 |
| NF1 | neurofibromin 1 | -0.0236394 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0235651 |
| PRELID2 | PRELI domain containing 2 | -0.0233804 |
| GDI2 | GDP dissociation inhibitor 2 | -0.0233778 |
| COMMD1 | copper metabolism (Murr1) domain containing 1 | -0.0232824 |
| CCDC138 | coiled-coil domain containing 138 | -0.0231137 |
| SRSF9 | serine/arginine-rich splicing factor 9 | -0.0230236 |
| USP3 | ubiquitin specific peptidase 3 | -0.0229501 |
| SRP54 | signal recognition particle 54kDa | -0.0229353 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.02279 |
| RPS15 | ribosomal protein S15 | -0.0226993 |
| PRKCE | protein kinase C, epsilon | -0.0226877 |
| FAM53C | family with sequence similarity 53, member C | -0.0225421 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0224897 |
| MRTFA | myocardin related transcription factor A | -0.0222634 |
| UBC | ubiquitin C | -0.0222516 |
| CTBP2 | C-terminal binding protein 2 | -0.0222443 |
| FAM3C | family with sequence similarity 3, member C | -0.0222182 |
| PARD3 | par-3 family cell polarity regulator | -0.0221912 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0220832 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.022079 |