Diammonium Glycyrrhizinate_SW480 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Diammonium Glycyrrhizinate perturbation in SW480 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Diammonium Glycyrrhizinate_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.131012
RPL23 ribosomal protein L23 0.124448
TMSB10 thymosin beta 10 0.0945755
RPS3 ribosomal protein S3 0.0918023
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0908943
RPS12 ribosomal protein S12 0.0887222
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0870444
RPS19 ribosomal protein S19 0.0859971
RPL26 ribosomal protein L26 0.0779133
INTS6 integrator complex subunit 6 0.0750445
MT2A metallothionein 2A 0.0735869
RPL3 ribosomal protein L3 0.0651425
EZR ezrin 0.061085
RACK1 receptor for activated C kinase 1 0.060844
EEF2 eukaryotic translation elongation factor 2 0.0585703
RPS17 ribosomal protein S17 0.0550639
RPL37A ribosomal protein L37a 0.0549274
NDRG1 N-myc downstream regulated 1 0.0501637
RPL18 ribosomal protein L18 0.0495569
RPL11 ribosomal protein L11 0.0492449
RPL21 ribosomal protein L21 0.0480756
FLNB filamin B, beta 0.0474006
RPL12 ribosomal protein L12 0.0472969
FTL ferritin, light polypeptide 0.0464087
ZFP36L1 ZFP36 ring finger protein-like 1 0.0411351
PCBP2 poly(rC) binding protein 2 0.0400251
TPI1 triosephosphate isomerase 1 0.0396834
RPL31 ribosomal protein L31 0.0382473
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.037049
RPL36 ribosomal protein L36 0.0361203
HMGA1 high mobility group AT-hook 1 0.0339425
RPL9 ribosomal protein L9 0.0331464
RPS14 ribosomal protein S14 0.0328229
ANO1 anoctamin 1, calcium activated chloride channel 0.0323638
PKM pyruvate kinase, muscle 0.0316411
AKAP12 A kinase (PRKA) anchor protein 12 0.0316034
MRPS6 mitochondrial ribosomal protein S6 0.0315184
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0314426
EEF1G eukaryotic translation elongation factor 1 gamma 0.0312816
ASPH aspartate beta-hydroxylase 0.0303101
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0302179
EGR1 early growth response 1 0.0300408
RPS4X ribosomal protein S4, X-linked 0.0296576
MSN moesin 0.0284153
YBX1 Y box binding protein 1 0.0280084
FLNA filamin A, alpha 0.0276148
PLEC plectin 0.0262655
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0260422
RPL7 ribosomal protein L7 0.0259346
RPL27 ribosomal protein L27 0.0254591
PFN1 profilin 1 0.0252303
ACTN1 actinin, alpha 1 0.0249851
SON SON DNA binding protein 0.0249664
VCL vinculin 0.0246979
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0245063
POTEF POTE ankyrin domain family, member F 0.0236805
MYH9 myosin, heavy chain 9, non-muscle 0.0236763
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0235505
ZSWIM6 zinc finger, SWIM-type containing 6 0.0231172
EMP1 epithelial membrane protein 1 0.0231024
IRS2 insulin receptor substrate 2 0.0230459
ENO2 enolase 2 (gamma, neuronal) 0.0222787
SEPTIN9 septin 9 0.0221807
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0213679
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0212005
MCL1 myeloid cell leukemia 1 0.0206399
UBAP2 ubiquitin associated protein 2 0.0205864
TGM2 transglutaminase 2 0.0205053
APLP2 amyloid beta (A4) precursor-like protein 2 0.0204833
LAMA4 laminin, alpha 4 0.0200881
FAM120A family with sequence similarity 120A 0.0198973
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.019831
TPM3 tropomyosin 3 0.0197
ESYT2 extended synaptotagmin-like protein 2 0.0196384
LAMA5 laminin, alpha 5 0.0195122
FNDC3B fibronectin type III domain containing 3B 0.0194294
ZCCHC7 zinc finger, CCHC domain containing 7 0.0194081
RPS27 ribosomal protein S27 0.0193778
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0192937
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0191633
PDLIM5 PDZ and LIM domain 5 0.0190147
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0189923
FOSL2 FOS-like antigen 2 0.0187154
SDK1 sidekick cell adhesion molecule 1 0.018675
SOX9 SRY (sex determining region Y)-box 9 0.0185906
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.0185462
SLC38A2 solute carrier family 38, member 2 0.0184493
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.0181503
RCOR1 REST corepressor 1 0.0181429
SMAD3 SMAD family member 3 0.0181339
RPL5 ribosomal protein L5 0.0180132
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0179435
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0178757
ZMIZ1 zinc finger, MIZ-type containing 1 0.0177121
RPL35 ribosomal protein L35 0.0177036
BRD2 bromodomain containing 2 0.0175367
HSPA8 heat shock 70kDa protein 8 0.0173899
ARF4 ADP-ribosylation factor 4 0.0172358
SRRM2 serine/arginine repetitive matrix 2 0.0172296
B2M beta-2-microglobulin 0.0166701

decreased expression

Symbol Name Standardized Value
NKD1 naked cuticle homolog 1 (Drosophila) -0.21411
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0883798
SYT1 synaptotagmin I -0.0818401
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0803744
TPT1 tumor protein, translationally-controlled 1 -0.0729172
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -0.0696103
PDE4D phosphodiesterase 4D, cAMP-specific -0.0592861
AOPEP aminopeptidase O (putative) -0.0578081
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.05373
WWOX WW domain containing oxidoreductase -0.0490224
TNS3 tensin 3 -0.0470364
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -0.046684
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0465458
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.0464772
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0462279
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.046102
ACTG1 actin gamma 1 -0.0451638
JMJD1C jumonji domain containing 1C -0.0447859
TMEM123 transmembrane protein 123 -0.0444338
RUNX1 runt-related transcription factor 1 -0.0422809
KPNB1 karyopherin (importin) beta 1 -0.0418974
TMSB4X thymosin beta 4, X-linked -0.0417603
ZMYND8 zinc finger, MYND-type containing 8 -0.0417595
RPL38 ribosomal protein L38 -0.0417333
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0403841
NF1 neurofibromin 1 -0.0392468
OXR1 oxidation resistance 1 -0.0386091
OSBPL3 oxysterol binding protein-like 3 -0.0377797
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 -0.0374075
RPS24 ribosomal protein S24 -0.037248
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0371625
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.036157
ADGRL2 adhesion G protein-coupled receptor L2 -0.0353771
CDH13 cadherin 13 -0.0351071
FAF1 Fas (TNFRSF6) associated factor 1 -0.0348459
RAD21 RAD21 homolog (S. pombe) -0.0346245
TCF12 transcription factor 12 -0.0344421
HMGB1 high mobility group box 1 -0.0334322
TAS2R14 taste receptor, type 2, member 14 -0.0333597
ZFR zinc finger RNA binding protein -0.0331369
DEK DEK proto-oncogene -0.0330496
CDK6 cyclin-dependent kinase 6 -0.0329807
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0327511
KRT8 keratin 8, type II -0.0318393
KDM3A lysine (K)-specific demethylase 3A -0.0316072
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.0311629
THOC2 THO complex 2 -0.0308805
SMYD3 SET and MYND domain containing 3 -0.0304746
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -0.0303071
HDAC8 histone deacetylase 8 -0.0301017
CANX calnexin -0.0299576
SPATA13 spermatogenesis associated 13 -0.0294806
MED13 mediator complex subunit 13 -0.0288333
SCAF11 SR-related CTD-associated factor 11 -0.0287785
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0285697
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0283817
CFDP1 craniofacial development protein 1 -0.0280589
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.0279187
ZBTB20 zinc finger and BTB domain containing 20 -0.027697
GCC2 GRIP and coiled-coil domain containing 2 -0.0276163
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0275096
MAML2 mastermind-like 2 (Drosophila) -0.0274594
NIPBL Nipped-B homolog (Drosophila) -0.0273587
RSL1D1 ribosomal L1 domain containing 1 -0.0271544
CCND1 cyclin D1 -0.0271392
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.026873
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0268693
ANLN anillin, actin binding protein -0.02678
SKAP1 src kinase associated phosphoprotein 1 -0.0267231
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0263927
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0262892
IER3 immediate early response 3 -0.0262009
GLG1 golgi glycoprotein 1 -0.0261585
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0252987
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0251488
RLF rearranged L-myc fusion -0.0251364
FRMD5 FERM domain containing 5 -0.0249716
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0249325
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0247567
STAU1 staufen double-stranded RNA binding protein 1 -0.0247004
GRIK5 glutamate receptor, ionotropic, kainate 5 -0.0246367
MACC1 metastasis associated in colon cancer 1 -0.0245579
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.0244128
BRWD3 bromodomain and WD repeat domain containing 3 -0.0243466
SENP5 SUMO1/sentrin specific peptidase 5 -0.0243456
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0243106
MSI2 musashi RNA-binding protein 2 -0.0241625
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0239362
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0239205
HNRNPK heterogeneous nuclear ribonucleoprotein K -0.0238146
BPTF bromodomain PHD finger transcription factor -0.0238144
FNDC3A fibronectin type III domain containing 3A -0.0236344
VDAC1 voltage-dependent anion channel 1 -0.0235304
SOX4 SRY (sex determining region Y)-box 4 -0.0235268
ATXN1 ataxin 1 -0.0234045
BCAS3 breast carcinoma amplified sequence 3 -0.0232486
DNAH14 dynein, axonemal, heavy chain 14 -0.0231245
BZW1 basic leucine zipper and W2 domains 1 -0.0231239
XPO1 exportin 1 -0.0229678
SBF2 SET binding factor 2 -0.0229314