Diffuse Astrocytoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0280785
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Genes

79 genes associated with the disease Diffuse Astrocytoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACVR1 activin A receptor, type I
ADAM12 ADAM metallopeptidase domain 12
ADAM23 ADAM metallopeptidase domain 23
AR androgen receptor
ATM ATM serine/threonine kinase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATRX alpha thalassemia/mental retardation syndrome X-linked
AZIN2 antizyme inhibitor 2
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAV1 caveolin 1, caveolae protein, 22kDa
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CHEK2 checkpoint kinase 2
COX2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCR3 chemokine (C-X-C motif) receptor 3
DLL3 delta-like 3 (Drosophila)
DMBT1 deleted in malignant brain tumors 1
EGFR epidermal growth factor receptor
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP7 fatty acid binding protein 7, brain
FGFR1 fibroblast growth factor receptor 1
FGFR4 fibroblast growth factor receptor 4
GADL1 glutamate decarboxylase-like 1
GFAP glial fibrillary acidic protein
H2AX H2A.X variant histone
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA2 high mobility group AT-hook 2
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
KIAA1549 KIAA1549
KRAS Kirsten rat sarcoma viral oncogene homolog
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MLH3 mutL homolog 3
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCOA3 nuclear receptor coactivator 3
NDRG1 N-myc downstream regulated 1
NF1 neurofibromin 1
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH4 notch 4
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLIG2 oligodendrocyte lineage transcription factor 2
PCNA proliferating cell nuclear antigen
PDCD10 programmed cell death 10
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PEA15 phosphoprotein enriched in astrocytes 15
PON1 paraoxonase 1
POU1F1 POU class 1 homeobox 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RCOR1 REST corepressor 1
REST RE1-silencing transcription factor
RMDN3 regulator of microtubule dynamics 3
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SOX2 SRY (sex determining region Y)-box 2
SYN1 synapsin I
SYP synaptophysin
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TSC2 tuberous sclerosis 2