Diffuse Panbronchiolitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Diffuse panbronchiolitis is a rare chronic inflammatory obstructive pulmonary disease primarily affecting the respiratory bronchioles throughout both lungs and inducing sinobronchial infection. Onset occurs in the second to fifth decade of life and manifests by chronic cough, exertional dyspnea, and sputum production. Most patients also have chronic paranasal sinusitis (Orphanet Rare Disease Ontology, Orphanet_171700)
External Link https://www.disgenet.org/browser/0/1/0/C0878555
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Genes

26 genes associated with the disease Diffuse Panbronchiolitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
CXCL8 chemokine (C-X-C motif) ligand 8
DPCR1 diffuse panbronchiolitis critical region 1
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
FAM46A family with sequence similarity 46, member A
FEV FEV (ETS oncogene family)
FLNB filamin B, beta
GC group-specific component (vitamin D binding protein)
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTF2H5 general transcription factor IIH, polypeptide 5
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
IL17A interleukin 17A
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
MBL2 mannose-binding lectin (protein C) 2, soluble
MLN motilin
MUC22 mucin 22
MUC5B mucin 5B, oligomeric mucus/gel-forming
NXF1 nuclear RNA export factor 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
USO1 USO1 vesicle transport factor