| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Digitoxin perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Digitoxin_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.31444 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.16147 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.131417 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.129816 |
| EXT1 | exostosin glycosyltransferase 1 | 0.114501 |
| PKM | pyruvate kinase, muscle | 0.106177 |
| HELZ | helicase with zinc finger | 0.105192 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.101406 |
| WDR45B | WD repeat domain 45B | 0.0997253 |
| PLAT | plasminogen activator, tissue | 0.0880181 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0876279 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0839934 |
| PTMA | prothymosin, alpha | 0.0804327 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0787221 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0772783 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0742807 |
| ENAH | enabled homolog (Drosophila) | 0.0738548 |
| VIM | vimentin | 0.0678251 |
| MED13 | mediator complex subunit 13 | 0.0657694 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0648909 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.064454 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0638865 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0635319 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0634588 |
| FAM13A | family with sequence similarity 13, member A | 0.0621349 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0617084 |
| RNF145 | ring finger protein 145 | 0.060277 |
| QKI | QKI, KH domain containing, RNA binding | 0.0600135 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0570927 |
| RPL37A | ribosomal protein L37a | 0.0557068 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0552511 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0540574 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0534388 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0531752 |
| TOP1 | topoisomerase (DNA) I | 0.0527484 |
| DIAPH1 | diaphanous-related formin 1 | 0.0524317 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0508429 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0505912 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0494264 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0489848 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0485269 |
| SETD5 | SET domain containing 5 | 0.0485258 |
| UBC | ubiquitin C | 0.0482139 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0479878 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0479635 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0472622 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0472468 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0466184 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.0463909 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.046238 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0459815 |
| SPAG9 | sperm associated antigen 9 | 0.0454721 |
| APP | amyloid beta (A4) precursor protein | 0.045278 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0452633 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0446654 |
| DTNA | dystrobrevin, alpha | 0.0437739 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0430914 |
| STC1 | stanniocalcin 1 | 0.0428851 |
| COPA | coatomer protein complex, subunit alpha | 0.0427033 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0426889 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0424868 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0423397 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0418699 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0418246 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.04157 |
| PCBP2 | poly(rC) binding protein 2 | 0.0406118 |
| SQSTM1 | sequestosome 1 | 0.0405549 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0404456 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0402872 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0402432 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0400283 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0397749 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0397097 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0391754 |
| SIK3 | SIK family kinase 3 | 0.0386589 |
| NDRG1 | N-myc downstream regulated 1 | 0.0386563 |
| ENO1 | enolase 1, (alpha) | 0.038533 |
| PCM1 | pericentriolar material 1 | 0.0384755 |
| USP34 | ubiquitin specific peptidase 34 | 0.0379167 |
| KIF5B | kinesin family member 5B | 0.0374254 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0373933 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0372299 |
| PHIP | pleckstrin homology domain interacting protein | 0.0372118 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0370935 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0370515 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0366611 |
| CUL3 | cullin 3 | 0.036403 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0359746 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0358299 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0355003 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0354157 |
| CENPF | centromere protein F, 350/400kDa | 0.0352301 |
| TPR | translocated promoter region, nuclear basket protein | 0.034549 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.034473 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0338588 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0338346 |
| TLK2 | tousled-like kinase 2 | 0.0338108 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0333601 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0333559 |
| MCL1 | myeloid cell leukemia 1 | 0.0326674 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SYT1 | synaptotagmin I | -0.0854943 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0760795 |
| MEIS2 | Meis homeobox 2 | -0.0691189 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0665237 |
| IGF2 | insulin-like growth factor 2 | -0.0632794 |
| LSAMP | limbic system-associated membrane protein | -0.0602966 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0472744 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.047178 |
| RNF213 | ring finger protein 213 | -0.0468222 |
| FMN1 | formin 1 | -0.0437844 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0436826 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0373978 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0363448 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.034873 |
| NREP | neuronal regeneration related protein | -0.0346517 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0336921 |
| ZNF804A | zinc finger protein 804A | -0.0325686 |
| SMYD3 | SET and MYND domain containing 3 | -0.0310049 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0288922 |
| FHIT | fragile histidine triad | -0.0286921 |
| FRMD4A | FERM domain containing 4A | -0.0267645 |
| HAS2 | hyaluronan synthase 2 | -0.0267589 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0261216 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0254566 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0246676 |
| BPTF | bromodomain PHD finger transcription factor | -0.0244633 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0243926 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0237917 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0236707 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0233095 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0230594 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0230463 |
| RIGI | RNA sensor RIG-I | -0.0222295 |
| RPL38 | ribosomal protein L38 | -0.0221915 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0220236 |
| RALYL | RALY RNA binding protein-like | -0.0214596 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | -0.021216 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.021216 |
| IGF2R | insulin-like growth factor 2 receptor | -0.021177 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.02116 |
| RPLP0 | ribosomal protein, large, P0 | -0.0207346 |
| ANGPT1 | angiopoietin 1 | -0.0206104 |
| AOPEP | aminopeptidase O (putative) | -0.0202813 |
| ATF6 | activating transcription factor 6 | -0.0202018 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0200264 |
| AUTS2 | autism susceptibility candidate 2 | -0.0199035 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0198771 |
| TBCK | TBC1 domain containing kinase | -0.0198508 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | -0.0197876 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0194381 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0194369 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0194198 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0193542 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0193135 |
| RAD51B | RAD51 paralog B | -0.0192009 |
| FN1 | fibronectin 1 | -0.0191505 |
| RAB30 | RAB30, member RAS oncogene family | -0.0187404 |
| PCNX4 | pecanex 4 | -0.018706 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.01862 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.0186098 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0180773 |
| TENM1 | teneurin transmembrane protein 1 | -0.0178925 |
| EXOC4 | exocyst complex component 4 | -0.0178683 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0176896 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0176147 |
| GPHN | gephyrin | -0.0175221 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0174779 |
| NRP1 | neuropilin 1 | -0.0174705 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0171723 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0169536 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0167454 |
| ZNF395 | zinc finger protein 395 | -0.0167126 |
| PLPP1 | phospholipid phosphatase 1 | -0.0166621 |
| TRIB2 | tribbles pseudokinase 2 | -0.0166207 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.0165289 |
| ARF1 | ADP-ribosylation factor 1 | -0.0163659 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0163372 |
| RNF150 | ring finger protein 150 | -0.0162753 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0162661 |
| METTL16 | methyltransferase like 16 | -0.016169 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0160243 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0158684 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0157699 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0156493 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0155611 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0155163 |
| SEPTIN2 | septin 2 | -0.0152309 |
| GOLM2 | golgi membrane protein 2 | -0.015198 |
| FRMD6 | FERM domain containing 6 | -0.0151424 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0150106 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0149524 |
| DACH2 | dachshund family transcription factor 2 | -0.014905 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0148892 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0148508 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0148505 |
| TENM4 | teneurin transmembrane protein 4 | -0.0146886 |
| ZNF652 | zinc finger protein 652 | -0.0146688 |
| PRKD1 | protein kinase D1 | -0.0144773 |
| RPS24 | ribosomal protein S24 | -0.014378 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0143361 |
