| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Digitoxin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Digitoxin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 0.122144 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.120323 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.114816 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.114687 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.114459 |
| INTS6 | integrator complex subunit 6 | 0.102752 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0836151 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0822483 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0810337 |
| EPHB2 | EPH receptor B2 | 0.0732448 |
| MSI2 | musashi RNA-binding protein 2 | 0.0669255 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0626517 |
| RUNX1 | runt-related transcription factor 1 | 0.0577527 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0564523 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0555166 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0550145 |
| RNF43 | ring finger protein 43 | 0.0526222 |
| VMP1 | vacuole membrane protein 1 | 0.0524501 |
| RNF213 | ring finger protein 213 | 0.0522454 |
| PRKCA | protein kinase C, alpha | 0.0493937 |
| MLPH | melanophilin | 0.0480029 |
| FAT1 | FAT atypical cadherin 1 | 0.0428431 |
| TTC39B | tetratricopeptide repeat domain 39B | 0.042454 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0383567 |
| ACTN4 | actinin, alpha 4 | 0.0381543 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0379302 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0353512 |
| PLSCR2 | phospholipid scramblase 2 | 0.0353452 |
| ITGA6 | integrin, alpha 6 | 0.0342291 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0341039 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0340892 |
| SMAD3 | SMAD family member 3 | 0.0339666 |
| UBC | ubiquitin C | 0.0339009 |
| ZNRF3 | zinc and ring finger 3 | 0.0335779 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0323534 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0322463 |
| SEPTIN9 | septin 9 | 0.0320741 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0315741 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0311074 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0309675 |
| TRIM2 | tripartite motif containing 2 | 0.0306534 |
| MX1 | MX dynamin-like GTPase 1 | 0.0304847 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0299963 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0299153 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0296964 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0295841 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0294273 |
| HDAC4 | histone deacetylase 4 | 0.0285937 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0280715 |
| TRERF1 | transcriptional regulating factor 1 | 0.0280711 |
| IFNGR1 | interferon gamma receptor 1 | 0.0272083 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0270866 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0270039 |
| PRELID2 | PRELI domain containing 2 | 0.0269139 |
| PKM | pyruvate kinase, muscle | 0.0266853 |
| TOX3 | TOX high mobility group box family member 3 | 0.0263473 |
| EXOC4 | exocyst complex component 4 | 0.0257671 |
| RAD51B | RAD51 paralog B | 0.0257268 |
| AOPEP | aminopeptidase O (putative) | 0.0256704 |
| AHNAK | AHNAK nucleoprotein | 0.0255611 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0254552 |
| FHIT | fragile histidine triad | 0.0247819 |
| KIAA1217 | KIAA1217 | 0.024694 |
| ETV6 | ets variant 6 | 0.0242514 |
| DOCK1 | dedicator of cytokinesis 1 | 0.023984 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0238688 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0238405 |
| SMYD3 | SET and MYND domain containing 3 | 0.0236373 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0234365 |
| ANXA4 | annexin A4 | 0.0233905 |
| ANXA2 | annexin A2 | 0.0232738 |
| MEIS2 | Meis homeobox 2 | 0.0231597 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0229709 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0227826 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0227329 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0226763 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0226399 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0226003 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0225681 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0217131 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0216224 |
| ENO1 | enolase 1, (alpha) | 0.0210838 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0210254 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0207943 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0207474 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0206596 |
| POTEF | POTE ankyrin domain family, member F | 0.020626 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0206125 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0204858 |
| FOXP1 | forkhead box P1 | 0.0201804 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0201449 |
| LMO7 | LIM domain 7 | 0.0200725 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0200037 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0196704 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0196576 |
| ATP11A | ATPase, class VI, type 11A | 0.0195846 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0191901 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0189893 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0185744 |
| WWOX | WW domain containing oxidoreductase | 0.0185093 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.101677 |
| SQSTM1 | sequestosome 1 | -0.0868524 |
| NDRG1 | N-myc downstream regulated 1 | -0.0702949 |
| FTL | ferritin, light polypeptide | -0.0626672 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0613402 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0598317 |
| ZNF292 | zinc finger protein 292 | -0.0531088 |
| B2M | beta-2-microglobulin | -0.047579 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0406989 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0397993 |
| FNIP1 | folliculin interacting protein 1 | -0.0385752 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0376904 |
| H1-0 | H1.0 linker histone | -0.0357942 |
| MUC20 | mucin 20, cell surface associated | -0.0345567 |
| RPS6 | ribosomal protein S6 | -0.0331664 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0327567 |
| HLA-B | major histocompatibility complex, class I, B | -0.03189 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0314142 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0293053 |
| RPL35A | ribosomal protein L35a | -0.0291752 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0280275 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0275658 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0267369 |
| SPATA13 | spermatogenesis associated 13 | -0.026315 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0257656 |
| KLF6 | Kruppel-like factor 6 | -0.0254682 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0242196 |
| RPS19 | ribosomal protein S19 | -0.0242052 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0241157 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0237389 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0237096 |
| IRS2 | insulin receptor substrate 2 | -0.0234891 |
| KLHL24 | kelch-like family member 24 | -0.0226903 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0224804 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0222651 |
| RLF | rearranged L-myc fusion | -0.0221054 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0214561 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0213094 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0211813 |
| ARF1 | ADP-ribosylation factor 1 | -0.0211782 |
| RPL34 | ribosomal protein L34 | -0.021039 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0206441 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0205553 |
| RBM39 | RNA binding motif protein 39 | -0.020457 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0202837 |
| APOL6 | apolipoprotein L, 6 | -0.0193491 |
| DST | dystonin | -0.0193276 |
| GOLGB1 | golgin B1 | -0.019265 |
| WDR45B | WD repeat domain 45B | -0.0192015 |
| RPL37A | ribosomal protein L37a | -0.0190452 |
| S100A10 | S100 calcium binding protein A10 | -0.0187353 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0183601 |
| MX2 | MX dynamin-like GTPase 2 | -0.0182628 |
| RNF149 | ring finger protein 149 | -0.0182564 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.018188 |
| RPLP1 | ribosomal protein, large, P1 | -0.0180307 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0179693 |
| CCNL1 | cyclin L1 | -0.0179548 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0177893 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0175533 |
| ADM | adrenomedullin | -0.0175288 |
| LMAN1 | lectin, mannose-binding, 1 | -0.017514 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.01745 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0174292 |
| XAF1 | XIAP associated factor 1 | -0.0171997 |
| RPL11 | ribosomal protein L11 | -0.0170377 |
| PLIN2 | perilipin 2 | -0.0169991 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0169778 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0168308 |
| SON | SON DNA binding protein | -0.0168304 |
| WWC1 | WW and C2 domain containing 1 | -0.0166934 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0166666 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0165925 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0165831 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0163947 |
| AGR2 | anterior gradient 2 | -0.0162166 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0162107 |
| RIOK3 | RIO kinase 3 | -0.0160216 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0159998 |
| DENND4C | DENN/MADD domain containing 4C | -0.0158628 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0155569 |
| RPL26 | ribosomal protein L26 | -0.0155403 |
| DSTN | destrin (actin depolymerizing factor) | -0.0154966 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.015469 |
| CSTB | cystatin B (stefin B) | -0.0152003 |
| GOLGA4 | golgin A4 | -0.014864 |
| RPL9 | ribosomal protein L9 | -0.014644 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0146176 |
| EPCAM | epithelial cell adhesion molecule | -0.0145957 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0143881 |
| RTN3 | reticulon 3 | -0.0142648 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.014262 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0141501 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0140327 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0138084 |
| TMSB4X | thymosin beta 4, X-linked | -0.013758 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0134984 |
| GOLGA2 | golgin A2 | -0.013494 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0134359 |
| INSIG1 | insulin induced gene 1 | -0.0133925 |
