| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Digitoxin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Digitoxin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.37619 |
| AHNAK | AHNAK nucleoprotein | 0.148272 |
| DOCK5 | dedicator of cytokinesis 5 | 0.123508 |
| ENO1 | enolase 1, (alpha) | 0.121804 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.116709 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.111748 |
| MYOF | myoferlin | 0.11084 |
| SULF1 | sulfatase 1 | 0.10724 |
| LMO7 | LIM domain 7 | 0.0957301 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.089972 |
| MTSS1 | metastasis suppressor 1 | 0.0877412 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0826208 |
| CD44 | CD44 molecule (Indian blood group) | 0.0820681 |
| EMP1 | epithelial membrane protein 1 | 0.0783302 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0780608 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0739151 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0705472 |
| ITGA6 | integrin, alpha 6 | 0.0677057 |
| NRG1 | neuregulin 1 | 0.0669052 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0668982 |
| ASPH | aspartate beta-hydroxylase | 0.0661034 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0622806 |
| UBC | ubiquitin C | 0.0612162 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0610855 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0580424 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0575798 |
| KRT17 | keratin 17, type I | 0.0565579 |
| CAPRIN2 | caprin family member 2 | 0.056285 |
| ANLN | anillin, actin binding protein | 0.0558693 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0537571 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0525431 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0503896 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0494114 |
| MSN | moesin | 0.0492021 |
| SMAD3 | SMAD family member 3 | 0.048473 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0466546 |
| OSMR | oncostatin M receptor | 0.0462367 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0459878 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0453001 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0447229 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0446451 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.043814 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0435093 |
| BCL2L1 | BCL2-like 1 | 0.0429732 |
| ACTN4 | actinin, alpha 4 | 0.04268 |
| EZR | ezrin | 0.0425455 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0423735 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0420717 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0409574 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0407636 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0403911 |
| ANKRD33B | ankyrin repeat domain 33B | 0.040347 |
| TGM2 | transglutaminase 2 | 0.0397674 |
| PLEC | plectin | 0.0396158 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0394892 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.038641 |
| PLAT | plasminogen activator, tissue | 0.0384769 |
| ANXA2 | annexin A2 | 0.0384205 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0383393 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0380029 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0379367 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0375649 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.037498 |
| GLG1 | golgi glycoprotein 1 | 0.0373258 |
| CANX | calnexin | 0.0370612 |
| NAV2 | neuron navigator 2 | 0.0367332 |
| MECOM | MDS1 and EVI1 complex locus | 0.0365124 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0364205 |
| NCOR2 | nuclear receptor corepressor 2 | 0.036085 |
| FOXP1 | forkhead box P1 | 0.0360078 |
| CMIP | c-Maf inducing protein | 0.0357917 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0356668 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0355207 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0354315 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0352557 |
| PKM | pyruvate kinase, muscle | 0.0351874 |
| RAI14 | retinoic acid induced 14 | 0.0350917 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0350717 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0348364 |
| ITGB4 | integrin, beta 4 | 0.0348014 |
| MCL1 | myeloid cell leukemia 1 | 0.034732 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0344006 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0343941 |
| SLTM | SAFB-like, transcription modulator | 0.0342508 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0339188 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0338752 |
| APP | amyloid beta (A4) precursor protein | 0.0335773 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0335244 |
| PGK1 | phosphoglycerate kinase 1 | 0.0333624 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0331985 |
| EGFR | epidermal growth factor receptor | 0.0330069 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0329918 |
| TPM3 | tropomyosin 3 | 0.0329454 |
| TNS3 | tensin 3 | 0.0328775 |
| EXOC6B | exocyst complex component 6B | 0.0327724 |
| LDHA | lactate dehydrogenase A | 0.0324204 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0323278 |
| CD9 | CD9 molecule | 0.032241 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0320573 |
| TPX2 | TPX2, microtubule-associated | 0.0320438 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.0783833 |
| RPS6 | ribosomal protein S6 | -0.0575561 |
| RPS8 | ribosomal protein S8 | -0.0440989 |
| MT2A | metallothionein 2A | -0.0439694 |
| RPLP1 | ribosomal protein, large, P1 | -0.0431457 |
| RPS21 | ribosomal protein S21 | -0.0408776 |
| RPL35A | ribosomal protein L35a | -0.0380885 |
| RPL11 | ribosomal protein L11 | -0.0380878 |
| RPLP2 | ribosomal protein, large, P2 | -0.03785 |
| RPS13 | ribosomal protein S13 | -0.0362782 |
| HLA-B | major histocompatibility complex, class I, B | -0.0358678 |
| RPL37A | ribosomal protein L37a | -0.0353799 |
| FTL | ferritin, light polypeptide | -0.0309769 |
| RPL37 | ribosomal protein L37 | -0.0306146 |
| RPS24 | ribosomal protein S24 | -0.029856 |
| RPL34 | ribosomal protein L34 | -0.0296504 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0295948 |
| RPS19 | ribosomal protein S19 | -0.02854 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0283137 |
| RPS3 | ribosomal protein S3 | -0.028011 |
| RPS29 | ribosomal protein S29 | -0.0278237 |
| RPS12 | ribosomal protein S12 | -0.0275725 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0274241 |
| RPS25 | ribosomal protein S25 | -0.0261599 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0260032 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.025536 |
| RPL9 | ribosomal protein L9 | -0.0251795 |
| RPS23 | ribosomal protein S23 | -0.0249427 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0248717 |
| SQSTM1 | sequestosome 1 | -0.0246348 |
| RPL31 | ribosomal protein L31 | -0.0236729 |
| TMSB4X | thymosin beta 4, X-linked | -0.0235946 |
| S100A2 | S100 calcium binding protein A2 | -0.0233325 |
| PTMA | prothymosin, alpha | -0.0232527 |
| B2M | beta-2-microglobulin | -0.0217935 |
| RPL27A | ribosomal protein L27a | -0.0213386 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0209725 |
| RPL36 | ribosomal protein L36 | -0.0206328 |
| RPL38 | ribosomal protein L38 | -0.0205485 |
| RPL19 | ribosomal protein L19 | -0.0204877 |
| S100A9 | S100 calcium binding protein A9 | -0.0203444 |
| RPS20 | ribosomal protein S20 | -0.0200127 |
| GNAS | GNAS complex locus | -0.0197245 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0196513 |
| RPLP0 | ribosomal protein, large, P0 | -0.0195326 |
| RPL26 | ribosomal protein L26 | -0.0192062 |
| RPS11 | ribosomal protein S11 | -0.0184882 |
| RPL12 | ribosomal protein L12 | -0.0182079 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0181207 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0181043 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0179949 |
| RPL28 | ribosomal protein L28 | -0.017991 |
| RPS16 | ribosomal protein S16 | -0.0179827 |
| RPS14 | ribosomal protein S14 | -0.0176065 |
| KLF6 | Kruppel-like factor 6 | -0.0174607 |
| RPL30 | ribosomal protein L30 | -0.0174523 |
| RPS27 | ribosomal protein S27 | -0.0174145 |
| RIGI | RNA sensor RIG-I | -0.0172877 |
| RPL13A | ribosomal protein L13a | -0.0172603 |
| RPL32 | ribosomal protein L32 | -0.0170569 |
| RPL35 | ribosomal protein L35 | -0.0169938 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.016854 |
| ADIRF | adipogenesis regulatory factor | -0.0168473 |
| RPS17 | ribosomal protein S17 | -0.016415 |
| PLTP | phospholipid transfer protein | -0.0158074 |
| ATF4 | activating transcription factor 4 | -0.0157028 |
| ADM | adrenomedullin | -0.0153975 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0152563 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0148814 |
| ARF1 | ADP-ribosylation factor 1 | -0.0147833 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0145759 |
| STC1 | stanniocalcin 1 | -0.0142659 |
| MT1E | metallothionein 1E | -0.0140092 |
| RPL23 | ribosomal protein L23 | -0.0137298 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0136143 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0135924 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0135257 |
| RPL8 | ribosomal protein L8 | -0.0134582 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0131144 |
| RPL27 | ribosomal protein L27 | -0.0130522 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0128655 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0127931 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0127734 |
| RPL7 | ribosomal protein L7 | -0.0123869 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0123424 |
| RPS10 | ribosomal protein S10 | -0.0121037 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -0.0120612 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0120385 |
| HMGB1 | high mobility group box 1 | -0.0119563 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0119349 |
| RPL36A | ribosomal protein L36a | -0.0118947 |
| RPL7A | ribosomal protein L7a | -0.0118564 |
| RPS4X | ribosomal protein S4, X-linked | -0.011782 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0116465 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0116381 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0115059 |
| RPL18 | ribosomal protein L18 | -0.0112924 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0112909 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0112126 |
| RPL5 | ribosomal protein L5 | -0.0112055 |
