| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Digitoxin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Digitoxin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.26704 |
| UBC | ubiquitin C | 0.191941 |
| FN1 | fibronectin 1 | 0.188366 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.14336 |
| ASPH | aspartate beta-hydroxylase | 0.119437 |
| FNDC3B | fibronectin type III domain containing 3B | 0.11624 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.102619 |
| EFNA5 | ephrin-A5 | 0.0970258 |
| LMO7 | LIM domain 7 | 0.0907943 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0894933 |
| ENO1 | enolase 1, (alpha) | 0.087503 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0809387 |
| ERBIN | erbb2 interacting protein | 0.0795908 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0763924 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0750279 |
| ACTG1 | actin gamma 1 | 0.0734035 |
| FBXO32 | F-box protein 32 | 0.0711398 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0691327 |
| MYO6 | myosin VI | 0.0676461 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0673404 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0667592 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0653317 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0647553 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0640574 |
| POTEF | POTE ankyrin domain family, member F | 0.0638719 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0634674 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.06114 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0599873 |
| KRT7 | keratin 7, type II | 0.0597989 |
| NAV2 | neuron navigator 2 | 0.0585261 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0577874 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0571197 |
| ANXA2 | annexin A2 | 0.0566884 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0558405 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0551127 |
| FLNB | filamin B, beta | 0.0549337 |
| PTK2 | protein tyrosine kinase 2 | 0.0543519 |
| LDHA | lactate dehydrogenase A | 0.0542575 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0525744 |
| SMAD3 | SMAD family member 3 | 0.0520065 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0518669 |
| CANX | calnexin | 0.0517658 |
| LAMC2 | laminin, gamma 2 | 0.0512786 |
| CDCP1 | CUB domain containing protein 1 | 0.0507108 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0499089 |
| NDRG1 | N-myc downstream regulated 1 | 0.0486826 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0486565 |
| PKM | pyruvate kinase, muscle | 0.0480064 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0473116 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0472022 |
| PCBP2 | poly(rC) binding protein 2 | 0.0462875 |
| AHNAK | AHNAK nucleoprotein | 0.0462671 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.045276 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0444241 |
| DTNA | dystrobrevin, alpha | 0.0435692 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0433704 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0429119 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0428374 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.042546 |
| TMF1 | TATA element modulatory factor 1 | 0.04251 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0416243 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0409344 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0403717 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0401749 |
| MYO1E | myosin IE | 0.0401526 |
| FNIP1 | folliculin interacting protein 1 | 0.0400928 |
| MYO5B | myosin VB | 0.0395344 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0390778 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0387877 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0387015 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0383636 |
| PLEC | plectin | 0.038159 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0378756 |
| PGK1 | phosphoglycerate kinase 1 | 0.037595 |
| CALU | calumenin | 0.0368484 |
| TPM4 | tropomyosin 4 | 0.0368055 |
| CTSB | cathepsin B | 0.036543 |
| TMEM165 | transmembrane protein 165 | 0.0362307 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0353524 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0352728 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0351787 |
| LAMB3 | laminin, beta 3 | 0.0351775 |
| DSPP | dentin sialophosphoprotein | 0.0350266 |
| OCLN | occludin | 0.0348795 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0347718 |
| SVIL | supervillin | 0.034377 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0343547 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0343284 |
| MYOF | myoferlin | 0.0341995 |
| TPM3 | tropomyosin 3 | 0.0341217 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0335749 |
| RAI14 | retinoic acid induced 14 | 0.033523 |
| CALR | calreticulin | 0.0335163 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0333559 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0331224 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0330562 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0329725 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0328983 |
| FAM3C | family with sequence similarity 3, member C | 0.0327251 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0325846 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0855045 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0577398 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.044115 |
| MT2A | metallothionein 2A | -0.043749 |
| FTL | ferritin, light polypeptide | -0.0414742 |
| RPLP1 | ribosomal protein, large, P1 | -0.041318 |
| RPL35A | ribosomal protein L35a | -0.0404546 |
| RPS19 | ribosomal protein S19 | -0.0396868 |
| G0S2 | G0/G1 switch 2 | -0.0385259 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0343633 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0330251 |
| RPLP0 | ribosomal protein, large, P0 | -0.0327847 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0319801 |
| RPLP2 | ribosomal protein, large, P2 | -0.0307846 |
| HMGA1 | high mobility group AT-hook 1 | -0.0276749 |
| RPS23 | ribosomal protein S23 | -0.0259801 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0243023 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.024274 |
| RPL9 | ribosomal protein L9 | -0.0219623 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0217541 |
| RPS8 | ribosomal protein S8 | -0.0209173 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0200622 |
| RPL12 | ribosomal protein L12 | -0.0194079 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0188273 |
| RPS14 | ribosomal protein S14 | -0.0186304 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0183396 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0182788 |
| RPS13 | ribosomal protein S13 | -0.018155 |
| RPS29 | ribosomal protein S29 | -0.0180234 |
| RPL36 | ribosomal protein L36 | -0.0180045 |
| RPS6 | ribosomal protein S6 | -0.0177808 |
| RPL8 | ribosomal protein L8 | -0.0172523 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0166961 |
| S100A9 | S100 calcium binding protein A9 | -0.0165635 |
| RPL34 | ribosomal protein L34 | -0.016068 |
| RPS10 | ribosomal protein S10 | -0.0159034 |
| FOSL1 | FOS-like antigen 1 | -0.0156311 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0155222 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0154042 |
| EGR1 | early growth response 1 | -0.0153766 |
| RPS21 | ribosomal protein S21 | -0.015321 |
| HMGB1 | high mobility group box 1 | -0.0152855 |
| KLF6 | Kruppel-like factor 6 | -0.0147925 |
| QKI | QKI, KH domain containing, RNA binding | -0.0140652 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.013919 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0138629 |
| RPL18 | ribosomal protein L18 | -0.0137974 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0134872 |
| USP3 | ubiquitin specific peptidase 3 | -0.0134533 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0133116 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.0132662 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.0129982 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0127542 |
| RBM25 | RNA binding motif protein 25 | -0.0126295 |
| RPS25 | ribosomal protein S25 | -0.0125341 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0125196 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0125037 |
| RPL38 | ribosomal protein L38 | -0.0123826 |
| IER3 | immediate early response 3 | -0.0123125 |
| NPR2 | natriuretic peptide receptor 2 | -0.0121306 |
| FAM162A | family with sequence similarity 162, member A | -0.0121001 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0120046 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0119087 |
| RPL32 | ribosomal protein L32 | -0.0114416 |
| PFN1 | profilin 1 | -0.0113485 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0113026 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0112182 |
| RPS3 | ribosomal protein S3 | -0.0111022 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0110266 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0109418 |
| RPL28 | ribosomal protein L28 | -0.0108444 |
| RPS27A | ribosomal protein S27a | -0.0108219 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0102614 |
| COL1A1 | collagen, type I, alpha 1 | -0.0100786 |
| GPX1 | glutathione peroxidase 1 | -0.010074 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.00997667 |
| TUBB4B | tubulin, beta 4B class IVb | -0.00988561 |
| S100A10 | S100 calcium binding protein A10 | -0.00974787 |
| COX7C | cytochrome c oxidase subunit VIIc | -0.00946684 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.00925125 |
| RPS5 | ribosomal protein S5 | -0.00909135 |
| RPL26 | ribosomal protein L26 | -0.00906366 |
| RPS15 | ribosomal protein S15 | -0.00905121 |
| UVRAG | UV radiation resistance associated | -0.00898064 |
| TUBA1B | tubulin, alpha 1b | -0.00896983 |
| RAB7A | RAB7A, member RAS oncogene family | -0.00895354 |
| RPS11 | ribosomal protein S11 | -0.00892135 |
| NOP58 | NOP58 ribonucleoprotein | -0.00890017 |
| RPS24 | ribosomal protein S24 | -0.00887287 |
| RPL36AL | ribosomal protein L36a-like | -0.00879678 |
| RPL11 | ribosomal protein L11 | -0.00874462 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.00858562 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0085462 |
| RPL23A | ribosomal protein L23a | -0.00845015 |
| HLA-B | major histocompatibility complex, class I, B | -0.00838678 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0083389 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00833157 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.00830668 |
| RPL27 | ribosomal protein L27 | -0.00825242 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.00819875 |
