| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Digitoxin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Digitoxin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.221104 |
| THBS1 | thrombospondin 1 | 0.179253 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.139475 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.130996 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.116826 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.114766 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0952185 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0951146 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0882524 |
| PEG10 | paternally expressed 10 | 0.0878104 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0876192 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0870029 |
| COL3A1 | collagen, type III, alpha 1 | 0.0835992 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0802361 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0778316 |
| POTEF | POTE ankyrin domain family, member F | 0.0754292 |
| COL5A2 | collagen, type V, alpha 2 | 0.0730498 |
| CALR | calreticulin | 0.06961 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0677504 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0667887 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0664986 |
| TMSB4X | thymosin beta 4, X-linked | 0.0642926 |
| EMP1 | epithelial membrane protein 1 | 0.0631969 |
| SPAG9 | sperm associated antigen 9 | 0.0592113 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0591836 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0561637 |
| VIM | vimentin | 0.055014 |
| ANXA2 | annexin A2 | 0.0543128 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0541273 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0510886 |
| DST | dystonin | 0.0506084 |
| RYBP | RING1 and YY1 binding protein | 0.0505412 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0504968 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0492325 |
| FAM171B | family with sequence similarity 171, member B | 0.0492152 |
| APP | amyloid beta (A4) precursor protein | 0.0487383 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0479442 |
| STAG2 | stromal antigen 2 | 0.0474085 |
| ACTN4 | actinin, alpha 4 | 0.0471985 |
| RBM39 | RNA binding motif protein 39 | 0.0471895 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0467732 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0463763 |
| HMGB2 | high mobility group box 2 | 0.0459657 |
| MB21D2 | Mab-21 domain containing 2 | 0.0453249 |
| CDC73 | cell division cycle 73 | 0.0448488 |
| UBC | ubiquitin C | 0.044509 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0440777 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0438806 |
| MATR3 | matrin 3 | 0.0436356 |
| QKI | QKI, KH domain containing, RNA binding | 0.0434985 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0434631 |
| HDAC9 | histone deacetylase 9 | 0.042624 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0421052 |
| ECT2 | epithelial cell transforming 2 | 0.0420858 |
| COL1A2 | collagen, type I, alpha 2 | 0.0416718 |
| CANX | calnexin | 0.0414776 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0413795 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0401424 |
| ANXA1 | annexin A1 | 0.0393416 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0391341 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0391104 |
| UPP1 | uridine phosphorylase 1 | 0.0390018 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0389027 |
| MEMO1 | mediator of cell motility 1 | 0.0388559 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0387975 |
| ANLN | anillin, actin binding protein | 0.037953 |
| TPX2 | TPX2, microtubule-associated | 0.0379117 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.037843 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0377983 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0369196 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0365634 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0364261 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0358938 |
| YAP1 | Yes-associated protein 1 | 0.035787 |
| PRKCI | protein kinase C, iota | 0.0352409 |
| KIF5B | kinesin family member 5B | 0.0351127 |
| ZNF217 | zinc finger protein 217 | 0.0350907 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0349795 |
| FBL | fibrillarin | 0.0345321 |
| LDHA | lactate dehydrogenase A | 0.034312 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.034227 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0337392 |
| MMP1 | matrix metallopeptidase 1 | 0.0336653 |
| CALU | calumenin | 0.0333653 |
| YBX1 | Y box binding protein 1 | 0.0330992 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0328438 |
| RHEB | Ras homolog enriched in brain | 0.0322776 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0317284 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0317275 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0314247 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0313768 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0313458 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0313456 |
| PCBP2 | poly(rC) binding protein 2 | 0.0307203 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0304509 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0302161 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0302065 |
| BRD2 | bromodomain containing 2 | 0.0301245 |
| BRD4 | bromodomain containing 4 | 0.0298954 |
| KIF1B | kinesin family member 1B | 0.0296847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.113166 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0999672 |
| TMSB10 | thymosin beta 10 | -0.0983021 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0749761 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.071155 |
| CADM2 | cell adhesion molecule 2 | -0.065719 |
| PTMA | prothymosin, alpha | -0.0632917 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0618712 |
| RPS8 | ribosomal protein S8 | -0.0539481 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0522493 |
| PCDH9 | protocadherin 9 | -0.0522276 |
| RAD51B | RAD51 paralog B | -0.0507312 |
| NPR2 | natriuretic peptide receptor 2 | -0.0478468 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0471994 |
| LRRC4C | leucine rich repeat containing 4C | -0.0463373 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0454773 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0445771 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0445412 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0429683 |
| GPC3 | glypican 3 | -0.0408509 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0388642 |
| CDH19 | cadherin 19, type 2 | -0.0380302 |
| RPS12 | ribosomal protein S12 | -0.0362922 |
| NTM | neurotrimin | -0.0353189 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0330256 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0329033 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0313994 |
| RPS21 | ribosomal protein S21 | -0.0306822 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0306337 |
| RPL35A | ribosomal protein L35a | -0.0301434 |
| RPLP2 | ribosomal protein, large, P2 | -0.0299821 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0296764 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0290935 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0287247 |
| RPLP1 | ribosomal protein, large, P1 | -0.0286588 |
| ARL13B | ADP-ribosylation factor-like 13B | -0.0284766 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.02836 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0278053 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0276218 |
| USP34 | ubiquitin specific peptidase 34 | -0.027313 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.026909 |
| RPS19 | ribosomal protein S19 | -0.0266775 |
| NEBL | nebulette | -0.0264883 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.02645 |
| PCDH7 | protocadherin 7 | -0.0264246 |
| TENM3 | teneurin transmembrane protein 3 | -0.026167 |
| RPL26 | ribosomal protein L26 | -0.0259224 |
| RPS3 | ribosomal protein S3 | -0.0259054 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0258832 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0256968 |
| GPHN | gephyrin | -0.0256802 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0255689 |
| PRELID2 | PRELI domain containing 2 | -0.0252794 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0249437 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0245438 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0239454 |
| FST | follistatin | -0.0238808 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0233882 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0233869 |
| RPL36A | ribosomal protein L36a | -0.023363 |
| RPS6 | ribosomal protein S6 | -0.0231884 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.0228559 |
| RPS16 | ribosomal protein S16 | -0.0227665 |
| SMYD3 | SET and MYND domain containing 3 | -0.0227146 |
| RPL9 | ribosomal protein L9 | -0.0226455 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0222788 |
| NHSL1 | NHS-like 1 | -0.0222514 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0214374 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0213779 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0213371 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.021101 |
| TRIM2 | tripartite motif containing 2 | -0.0209259 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0208786 |
| ZNF385D | zinc finger protein 385D | -0.0208769 |
| FOXP2 | forkhead box P2 | -0.0207541 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0207301 |
| MEF2C | myocyte enhancer factor 2C | -0.0206269 |
| ATXN1 | ataxin 1 | -0.0206166 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.020516 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0202669 |
| RPS13 | ribosomal protein S13 | -0.0202408 |
| LPIN2 | lipin 2 | -0.0200669 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0198645 |
| SYT1 | synaptotagmin I | -0.0192002 |
| OSBPL6 | oxysterol binding protein-like 6 | -0.0191742 |
| RPL36 | ribosomal protein L36 | -0.0190693 |
| CDK13 | cyclin-dependent kinase 13 | -0.0190533 |
| S100A9 | S100 calcium binding protein A9 | -0.0190495 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0188974 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0187834 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0186366 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0185566 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0184823 |
| NOP58 | NOP58 ribonucleoprotein | -0.0183628 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0183275 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0183168 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0183021 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0180529 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0180229 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0178524 |
