| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Digitoxin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Digitoxin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.126607 |
| LDHA | lactate dehydrogenase A | 0.12466 |
| WAC | WW domain containing adaptor with coiled-coil | 0.115127 |
| RBM39 | RNA binding motif protein 39 | 0.110726 |
| PKM | pyruvate kinase, muscle | 0.0941384 |
| JUN | jun proto-oncogene | 0.0879375 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0793775 |
| ENO1 | enolase 1, (alpha) | 0.0789243 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0786449 |
| UBC | ubiquitin C | 0.0763974 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0746324 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0725289 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0724757 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0710649 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0689967 |
| PRKCA | protein kinase C, alpha | 0.0689905 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0673564 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0629563 |
| VIM | vimentin | 0.0627442 |
| SQSTM1 | sequestosome 1 | 0.0621954 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.061643 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0608773 |
| DIAPH1 | diaphanous-related formin 1 | 0.0586137 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0586091 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0583206 |
| TPX2 | TPX2, microtubule-associated | 0.0572912 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0569848 |
| SPAG9 | sperm associated antigen 9 | 0.0565567 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0556924 |
| MATR3 | matrin 3 | 0.0544516 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0534632 |
| AHNAK | AHNAK nucleoprotein | 0.0532805 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0532289 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0526565 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0514535 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0504673 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0500937 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.04984 |
| MED13 | mediator complex subunit 13 | 0.0487327 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0485896 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0479608 |
| DST | dystonin | 0.0466963 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.045924 |
| SET | SET nuclear proto-oncogene | 0.0457003 |
| ECT2 | epithelial cell transforming 2 | 0.0449668 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0446697 |
| SEPTIN2 | septin 2 | 0.0445048 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0442991 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0424358 |
| CD44 | CD44 molecule (Indian blood group) | 0.0423116 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0419797 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0417261 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.041223 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0410892 |
| CRY1 | cryptochrome circadian clock 1 | 0.040955 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.040925 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0407862 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0406395 |
| CALR | calreticulin | 0.0404429 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0403743 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0396312 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0396102 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0395036 |
| ZNF207 | zinc finger protein 207 | 0.0394901 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0394732 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0393487 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0386752 |
| ERBIN | erbb2 interacting protein | 0.0385144 |
| RBM25 | RNA binding motif protein 25 | 0.0379661 |
| ATP13A3 | ATPase type 13A3 | 0.0373892 |
| TOP1 | topoisomerase (DNA) I | 0.0370226 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0364658 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0363308 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0360399 |
| TXNIP | thioredoxin interacting protein | 0.0359951 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0357146 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0357142 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0355237 |
| PARD3 | par-3 family cell polarity regulator | 0.0355136 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.035465 |
| CANX | calnexin | 0.0353141 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0352126 |
| ATXN2 | ataxin 2 | 0.0351358 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0347047 |
| PCBP2 | poly(rC) binding protein 2 | 0.0346457 |
| NUP58 | nucleoporin 58 | 0.0343216 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0343097 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0340869 |
| NGLY1 | N-glycanase 1 | 0.0339575 |
| SMAD3 | SMAD family member 3 | 0.0337626 |
| TXNRD1 | thioredoxin reductase 1 | 0.033673 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0335187 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0334185 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.033295 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0331832 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0330594 |
| MSN | moesin | 0.0330445 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.0330412 |
| RNF145 | ring finger protein 145 | 0.0330236 |
| NUP98 | nucleoporin 98kDa | 0.0329488 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.13889 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0777701 |
| FTL | ferritin, light polypeptide | -0.0541321 |
| RPLP1 | ribosomal protein, large, P1 | -0.0455207 |
| RPL19 | ribosomal protein L19 | -0.0455046 |
| RPL35A | ribosomal protein L35a | -0.045139 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0445988 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0371221 |
| RPS11 | ribosomal protein S11 | -0.0352968 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0341981 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0340531 |
| IER3 | immediate early response 3 | -0.033981 |
| RPS29 | ribosomal protein S29 | -0.033829 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0328347 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0305039 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0290086 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0287735 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0285099 |
| PURA | purine-rich element binding protein A | -0.0281088 |
| MT1X | metallothionein 1X | -0.0280477 |
| TAOK3 | TAO kinase 3 | -0.0277053 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0272312 |
| FBXO11 | F-box protein 11 | -0.0271773 |
| FNBP1 | formin binding protein 1 | -0.0269681 |
| BBX | bobby sox homolog (Drosophila) | -0.0269403 |
| RORA | RAR-related orphan receptor A | -0.0269157 |
| GPC6 | glypican 6 | -0.0264656 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0264237 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0262892 |
| ARF1 | ADP-ribosylation factor 1 | -0.0262702 |
| RPS6 | ribosomal protein S6 | -0.0256615 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0251372 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0249892 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0245712 |
| ATG12 | autophagy related 12 | -0.0245411 |
| RPS13 | ribosomal protein S13 | -0.0244725 |
| RPS8 | ribosomal protein S8 | -0.0239907 |
| SNX14 | sorting nexin 14 | -0.0237643 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0235301 |
| HM13 | histocompatibility (minor) 13 | -0.0233434 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0233311 |
| RPL36 | ribosomal protein L36 | -0.0229282 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.022875 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0226998 |
| RPL11 | ribosomal protein L11 | -0.0225367 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.022497 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0219937 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0219243 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0217367 |
| MLF1 | myeloid leukemia factor 1 | -0.0217092 |
| RPS14 | ribosomal protein S14 | -0.0215428 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0214793 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0214436 |
| RPS19 | ribosomal protein S19 | -0.0212143 |
| NIN | ninein (GSK3B interacting protein) | -0.021191 |
| RPL31 | ribosomal protein L31 | -0.0211059 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0211043 |
| RPL38 | ribosomal protein L38 | -0.0209212 |
| PHF14 | PHD finger protein 14 | -0.0206961 |
| RPL12 | ribosomal protein L12 | -0.0206917 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0206504 |
| EGR1 | early growth response 1 | -0.0206252 |
| JAK1 | Janus kinase 1 | -0.0205553 |
| RPS25 | ribosomal protein S25 | -0.0205285 |
| S100A6 | S100 calcium binding protein A6 | -0.0202896 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0202496 |
| CDK13 | cyclin-dependent kinase 13 | -0.0201337 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0200947 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.0199107 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0197894 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0197886 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0197483 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0197345 |
| CMC1 | C-x(9)-C motif containing 1 | -0.019684 |
| HLA-B | major histocompatibility complex, class I, B | -0.0194087 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0194037 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0193826 |
| RAN | RAN, member RAS oncogene family | -0.0193192 |
| PCNX1 | pecanex 1 | -0.0192155 |
| MICU2 | mitochondrial calcium uptake 2 | -0.0192112 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0191102 |
| PCNX2 | pecanex 2 | -0.0190909 |
| MRPL13 | mitochondrial ribosomal protein L13 | -0.019042 |
| RFX7 | regulatory factor X, 7 | -0.0190388 |
| PDCD10 | programmed cell death 10 | -0.0190168 |
| MTDH | metadherin | -0.0189715 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0188107 |
| RPL18 | ribosomal protein L18 | -0.0187685 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0186204 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.0184606 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0181836 |
| RPL37A | ribosomal protein L37a | -0.0180223 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0179937 |
| METAP2 | methionyl aminopeptidase 2 | -0.0179695 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0179631 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 | -0.0178688 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0178672 |
| IRS2 | insulin receptor substrate 2 | -0.0177706 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0177648 |
| PLAUR | plasminogen activator, urokinase receptor | -0.01774 |
