Digoxin Gene Set

Dataset	DrugBank Drug Targets
Category	physical interactions
Type	drug
Description	Digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small. (Chemical Entities of Biological Interest Ontology, CHEBI_4551)
External Link	http://www.drugbank.ca/drugs/DB00390
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Genes

15 interacting proteins for the Digoxin drug from the curated DrugBank Drug Targets dataset.

Symbol	Name
ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11
ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide
CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4
SLC22A8	solute carrier family 22 (organic anion transporter), member 8
SLC51A	solute carrier family 51, alpha subunit
SLC51B	solute carrier family 51, beta subunit
SLCO1A2	solute carrier organic anion transporter family, member 1A2
SLCO1B1	solute carrier organic anion transporter family, member 1B1
SLCO1B3	solute carrier organic anion transporter family, member 1B3
SLCO1C1	solute carrier organic anion transporter family, member 1C1
SLCO2B1	solute carrier organic anion transporter family, member 2B1
SLCO4A1	solute carrier organic anion transporter family, member 4A1
SLCO4C1	solute carrier organic anion transporter family, member 4C1