| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.212197 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.167519 |
| VIM | vimentin | 0.131628 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.125639 |
| MT2A | metallothionein 2A | 0.0910304 |
| LDHA | lactate dehydrogenase A | 0.0857623 |
| CD44 | CD44 molecule (Indian blood group) | 0.075237 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0704935 |
| NDRG1 | N-myc downstream regulated 1 | 0.0632903 |
| FLNB | filamin B, beta | 0.0512983 |
| SEPTIN9 | septin 9 | 0.0475732 |
| UBC | ubiquitin C | 0.040705 |
| MYADM | myeloid-associated differentiation marker | 0.0402693 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0371846 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0370621 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0356698 |
| TPM3 | tropomyosin 3 | 0.0350537 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0341632 |
| COL1A2 | collagen, type I, alpha 2 | 0.0334787 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0333479 |
| CENPF | centromere protein F, 350/400kDa | 0.0305127 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0302917 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0299765 |
| FBN1 | fibrillin 1 | 0.0299015 |
| COPA | coatomer protein complex, subunit alpha | 0.0298864 |
| CALR | calreticulin | 0.0298632 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0294778 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0286076 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0283693 |
| MSN | moesin | 0.0279128 |
| ANXA2 | annexin A2 | 0.0265361 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0261736 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0251149 |
| PCM1 | pericentriolar material 1 | 0.0249566 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0248397 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0247813 |
| TGFB1 | transforming growth factor, beta 1 | 0.0247549 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0238268 |
| AXL | AXL receptor tyrosine kinase | 0.0238232 |
| TXNIP | thioredoxin interacting protein | 0.0233698 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.02327 |
| PKM | pyruvate kinase, muscle | 0.0231875 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0226967 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0226183 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0224738 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0224192 |
| ZNF207 | zinc finger protein 207 | 0.0223306 |
| STC1 | stanniocalcin 1 | 0.0217899 |
| PCBP2 | poly(rC) binding protein 2 | 0.0216963 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.021405 |
| C1D | C1D nuclear receptor corepressor | 0.021361 |
| MT1X | metallothionein 1X | 0.0213488 |
| FTL | ferritin, light polypeptide | 0.0212254 |
| APP | amyloid beta (A4) precursor protein | 0.0209717 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0207308 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0204121 |
| OPTN | optineurin | 0.0202989 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0202919 |
| FNDC3B | fibronectin type III domain containing 3B | 0.020129 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0199266 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0197197 |
| MLXIP | MLX interacting protein | 0.0196986 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0196059 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0195236 |
| MYO9B | myosin IXB | 0.0194581 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0193739 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0193596 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0191601 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | 0.0191213 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.0190641 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0190334 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0190217 |
| CDK19 | cyclin-dependent kinase 19 | 0.0190132 |
| MYO9A | myosin IXA | 0.0189938 |
| BSG | basigin (Ok blood group) | 0.0189151 |
| MCL1 | myeloid cell leukemia 1 | 0.0188598 |
| CDCA2 | cell division cycle associated 2 | 0.0188061 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0184211 |
| MKI67 | marker of proliferation Ki-67 | 0.0182966 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0182692 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0179998 |
| DSTN | destrin (actin depolymerizing factor) | 0.0179679 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.017912 |
| SMAD3 | SMAD family member 3 | 0.017878 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0178645 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0178556 |
| NOTCH2 | notch 2 | 0.0175229 |
| PFKP | phosphofructokinase, platelet | 0.0174789 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0174541 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0173832 |
| EZR | ezrin | 0.0172716 |
| UBAP1 | ubiquitin associated protein 1 | 0.01721 |
| XPO1 | exportin 1 | 0.0171532 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0170941 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.017074 |
| SUCO | SUN domain containing ossification factor | 0.0170422 |
| KIF13A | kinesin family member 13A | 0.0169204 |
| CTSB | cathepsin B | 0.0168909 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0168765 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0168505 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.165164 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.097299 |
| LOX | lysyl oxidase | -0.0948323 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0878402 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0757463 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0725422 |
| FN1 | fibronectin 1 | -0.0700883 |
| AHNAK | AHNAK nucleoprotein | -0.0699732 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0598839 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0596517 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.057806 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0529087 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0487927 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0472511 |
| RIGI | RNA sensor RIG-I | -0.0470063 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0463679 |
| CDH13 | cadherin 13 | -0.0455455 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0446175 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.044507 |
| THBS2 | thrombospondin 2 | -0.0434398 |
| AUTS2 | autism susceptibility candidate 2 | -0.0431246 |
| FGF13 | fibroblast growth factor 13 | -0.0430602 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0430579 |
| FRMD5 | FERM domain containing 5 | -0.0410907 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0409677 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0399313 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0397013 |
| COL5A1 | collagen, type V, alpha 1 | -0.0394345 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0393427 |
| GPC6 | glypican 6 | -0.0373704 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0372033 |
| JAZF1 | JAZF zinc finger 1 | -0.0358599 |
| SYT1 | synaptotagmin I | -0.0343147 |
| FRMD4A | FERM domain containing 4A | -0.0335148 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0331484 |
| NAV2 | neuron navigator 2 | -0.0328161 |
| SLFN5 | schlafen family member 5 | -0.0327682 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0321157 |
| MX2 | MX dynamin-like GTPase 2 | -0.0317223 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0316112 |
| VEGFC | vascular endothelial growth factor C | -0.0315288 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0311178 |
| TDRD7 | tudor domain containing 7 | -0.0308277 |
| SP100 | SP100 nuclear antigen | -0.0306535 |
| DST | dystonin | -0.0304633 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0303805 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0299462 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0295422 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.029365 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0292191 |
| PARD3 | par-3 family cell polarity regulator | -0.0283198 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.027693 |
| LRRC49 | leucine rich repeat containing 49 | -0.0273879 |
| MEIS2 | Meis homeobox 2 | -0.0272263 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0271653 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0268686 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.026719 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0245502 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0242623 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0240756 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0237172 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.023614 |
| TMSB10 | thymosin beta 10 | -0.023387 |
| RASAL2 | RAS protein activator like 2 | -0.0233611 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0232112 |
| TNS3 | tensin 3 | -0.0229129 |
| IL7R | interleukin 7 receptor | -0.0228031 |
| CANX | calnexin | -0.0224555 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0224144 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0221625 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0221346 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0220179 |
| SRPK2 | SRSF protein kinase 2 | -0.0215314 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0214091 |
| TENM3 | teneurin transmembrane protein 3 | -0.0214007 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0209023 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0208981 |
| TMSB4X | thymosin beta 4, X-linked | -0.0208283 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0208081 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0203061 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.0200651 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | -0.0200129 |
| JAK2 | Janus kinase 2 | -0.0200102 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0198411 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0197003 |
| TCF12 | transcription factor 12 | -0.0196577 |
| EHBP1 | EH domain binding protein 1 | -0.0190888 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0190712 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0185724 |
| RRBP1 | ribosome binding protein 1 | -0.0185702 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0185061 |
| PLSCR1 | phospholipid scramblase 1 | -0.0184832 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0184501 |
| FSTL1 | follistatin-like 1 | -0.0184233 |
| SPAG9 | sperm associated antigen 9 | -0.0183316 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0182199 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0181393 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0180405 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0180348 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0180347 |
