| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dihydroartemisinin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.379999 |
| COL6A3 | collagen, type VI, alpha 3 | 0.227567 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.201212 |
| VEGFA | vascular endothelial growth factor A | 0.164758 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.15045 |
| LDHA | lactate dehydrogenase A | 0.115853 |
| CANX | calnexin | 0.103047 |
| NDRG1 | N-myc downstream regulated 1 | 0.0960845 |
| RPL3 | ribosomal protein L3 | 0.0762968 |
| FBN1 | fibrillin 1 | 0.0679655 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0670475 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0569304 |
| APP | amyloid beta (A4) precursor protein | 0.0551581 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0522726 |
| TPM4 | tropomyosin 4 | 0.0518099 |
| PLEC | plectin | 0.0509393 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0477852 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0468798 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0430045 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0413072 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0411827 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0409712 |
| LOXL2 | lysyl oxidase-like 2 | 0.0405458 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0400456 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0372962 |
| CALR | calreticulin | 0.0367137 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0356134 |
| FLNA | filamin A, alpha | 0.0351871 |
| RPL18A | ribosomal protein L18a | 0.0325319 |
| CDH13 | cadherin 13 | 0.0322276 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0321457 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0319729 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0316447 |
| RPL13A | ribosomal protein L13a | 0.0300278 |
| ASPH | aspartate beta-hydroxylase | 0.0299334 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0297995 |
| MSN | moesin | 0.0290398 |
| COL5A1 | collagen, type V, alpha 1 | 0.0282794 |
| COL1A2 | collagen, type I, alpha 2 | 0.0281356 |
| AXL | AXL receptor tyrosine kinase | 0.027111 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.024756 |
| HDLBP | high density lipoprotein binding protein | 0.0245316 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.02427 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0240295 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0235249 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.023321 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0232303 |
| DST | dystonin | 0.0228701 |
| MAP1B | microtubule-associated protein 1B | 0.02267 |
| PTK2 | protein tyrosine kinase 2 | 0.0225048 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0223247 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0220417 |
| INHBA | inhibin, beta A | 0.0217303 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0213592 |
| PRELID2 | PRELI domain containing 2 | 0.0212802 |
| VCAN | versican | 0.0212718 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0209995 |
| FLNB | filamin B, beta | 0.0204046 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0200894 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0200076 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0199664 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.019495 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0192345 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0191246 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0190295 |
| TPM2 | tropomyosin 2 (beta) | 0.0190192 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0182762 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0180902 |
| SMAD3 | SMAD family member 3 | 0.0179884 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0179079 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0178178 |
| CPNE1 | copine I | 0.0177581 |
| MCL1 | myeloid cell leukemia 1 | 0.0176848 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0175822 |
| HYOU1 | hypoxia up-regulated 1 | 0.0173337 |
| OPTN | optineurin | 0.0171772 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.0170736 |
| TPM3 | tropomyosin 3 | 0.0168176 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0167934 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0163984 |
| SET | SET nuclear proto-oncogene | 0.01626 |
| YEATS2 | YEATS domain containing 2 | 0.0161394 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0160739 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.016032 |
| PCBP2 | poly(rC) binding protein 2 | 0.0160283 |
| NAV1 | neuron navigator 1 | 0.0159294 |
| HMGA2 | high mobility group AT-hook 2 | 0.0159106 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0157943 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0157101 |
| ATXN1 | ataxin 1 | 0.0156906 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0156876 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0156203 |
| MTSS1 | metastasis suppressor 1 | 0.0154085 |
| MYO10 | myosin X | 0.0152916 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0150637 |
| RPS4X | ribosomal protein S4, X-linked | 0.0149682 |
| CALU | calumenin | 0.0148056 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0147238 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0145991 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0145375 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.294132 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139108 |
| IER3 | immediate early response 3 | -0.0751091 |
| TMSB10 | thymosin beta 10 | -0.0687522 |
| FN1 | fibronectin 1 | -0.0649112 |
| VIM | vimentin | -0.0622002 |
| COL1A1 | collagen, type I, alpha 1 | -0.0531349 |
| MT2A | metallothionein 2A | -0.0531211 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0414934 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0384909 |
| ACTG1 | actin gamma 1 | -0.0380869 |
| FTL | ferritin, light polypeptide | -0.0372784 |
| LOX | lysyl oxidase | -0.0343363 |
| RPL35A | ribosomal protein L35a | -0.032729 |
| RPS8 | ribosomal protein S8 | -0.0315431 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0277778 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0260093 |
| RPS24 | ribosomal protein S24 | -0.0236619 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0219184 |
| S100A9 | S100 calcium binding protein A9 | -0.0217066 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0215514 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0191551 |
| RPLP1 | ribosomal protein, large, P1 | -0.0188867 |
| RPL28 | ribosomal protein L28 | -0.0187669 |
| ANXA2 | annexin A2 | -0.0183254 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0182207 |
| RPLP0 | ribosomal protein, large, P0 | -0.0180326 |
| RPL34 | ribosomal protein L34 | -0.0176091 |
| RPS6 | ribosomal protein S6 | -0.017561 |
| RPL30 | ribosomal protein L30 | -0.0175159 |
| PXDN | peroxidasin | -0.0173899 |
| RPS5 | ribosomal protein S5 | -0.0172508 |
| S100A10 | S100 calcium binding protein A10 | -0.0171686 |
| RPL12 | ribosomal protein L12 | -0.0170929 |
| RACK1 | receptor for activated C kinase 1 | -0.0170219 |
| ZNF292 | zinc finger protein 292 | -0.0169086 |
| RPS16 | ribosomal protein S16 | -0.0162428 |
| PTMA | prothymosin, alpha | -0.0161996 |
| S100A6 | S100 calcium binding protein A6 | -0.0156746 |
| RPS19 | ribosomal protein S19 | -0.0152996 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0152522 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0149641 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0147383 |
| RPS25 | ribosomal protein S25 | -0.0146593 |
| QKI | QKI, KH domain containing, RNA binding | -0.0142404 |
| RPLP2 | ribosomal protein, large, P2 | -0.0141796 |
| RHEB | Ras homolog enriched in brain | -0.0141736 |
| CAVIN1 | caveolae associated protein 1 | -0.0141733 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0140963 |
| THY1 | Thy-1 cell surface antigen | -0.0139727 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0139533 |
| COL3A1 | collagen, type III, alpha 1 | -0.0136847 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0136804 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0136372 |
| RPL32 | ribosomal protein L32 | -0.0133045 |
| SEPTIN7 | septin 7 | -0.0131523 |
| RPL26 | ribosomal protein L26 | -0.0129953 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0127972 |
| IL6ST | interleukin 6 signal transducer | -0.0127221 |
| RPS23 | ribosomal protein S23 | -0.0125787 |
| RPS2 | ribosomal protein S2 | -0.0125242 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0125183 |
| FAM162A | family with sequence similarity 162, member A | -0.0124908 |
| UBC | ubiquitin C | -0.0122943 |
| RYBP | RING1 and YY1 binding protein | -0.0122693 |
| TUBA1B | tubulin, alpha 1b | -0.0118804 |
| EHD2 | EH-domain containing 2 | -0.0118472 |
| RPL36 | ribosomal protein L36 | -0.0117575 |
| RLF | rearranged L-myc fusion | -0.0110213 |
| WASF2 | WAS protein family, member 2 | -0.0109526 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0108091 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0107773 |
| RPL23 | ribosomal protein L23 | -0.0107579 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0107078 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0106322 |
| TKT | transketolase | -0.0105966 |
| HMGB1 | high mobility group box 1 | -0.0105053 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0102919 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0102378 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0102218 |
| TPI1 | triosephosphate isomerase 1 | -0.0101241 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0100761 |
| RPL36A | ribosomal protein L36a | -0.00995279 |
| HMGA1 | high mobility group AT-hook 1 | -0.00990348 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00981853 |
| RPS20 | ribosomal protein S20 | -0.00970258 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.00955196 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.00948932 |
| RTN3 | reticulon 3 | -0.00945429 |
| MT1X | metallothionein 1X | -0.00928363 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00922233 |
| ARF1 | ADP-ribosylation factor 1 | -0.00915254 |
| RPS21 | ribosomal protein S21 | -0.00913187 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00907527 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00903267 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00895378 |
| RPL15 | ribosomal protein L15 | -0.0089347 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.00893096 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00887652 |
| RPL31 | ribosomal protein L31 | -0.00883522 |
