| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| C3 | complement component 3 | 0.195766 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.18099 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.127049 |
| RPL3 | ribosomal protein L3 | 0.118298 |
| SVIL | supervillin | 0.1135 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0925048 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0801329 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0764962 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.07003 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0675894 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0657832 |
| MCL1 | myeloid cell leukemia 1 | 0.0644858 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.057734 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0565781 |
| ITGAV | integrin, alpha V | 0.0556735 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0537066 |
| TNS1 | tensin 1 | 0.0517062 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0510968 |
| FAM107B | family with sequence similarity 107, member B | 0.0498519 |
| MRTFA | myocardin related transcription factor A | 0.0488606 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0478576 |
| LDHA | lactate dehydrogenase A | 0.0476123 |
| TXNRD1 | thioredoxin reductase 1 | 0.0475564 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0475213 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.047413 |
| VCL | vinculin | 0.0458699 |
| PCBP2 | poly(rC) binding protein 2 | 0.0455906 |
| TOP1 | topoisomerase (DNA) I | 0.045579 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0454215 |
| BCL2L1 | BCL2-like 1 | 0.0448936 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0441216 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0434406 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0402476 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0397469 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0397144 |
| RPL37A | ribosomal protein L37a | 0.0393138 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0392467 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0388382 |
| SMAD3 | SMAD family member 3 | 0.0387507 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0385844 |
| DIAPH1 | diaphanous-related formin 1 | 0.037546 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0360657 |
| DSPP | dentin sialophosphoprotein | 0.0358989 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.035699 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0339062 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0336564 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0334667 |
| PANK3 | pantothenate kinase 3 | 0.0329749 |
| PTK2 | protein tyrosine kinase 2 | 0.0327939 |
| PLEC | plectin | 0.0324801 |
| TCIM | transcriptional and immune response regulator | 0.0320324 |
| VEGFA | vascular endothelial growth factor A | 0.0320286 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0317277 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0305906 |
| RTN4 | reticulon 4 | 0.0301114 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0296877 |
| RPL7 | ribosomal protein L7 | 0.0294712 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0293222 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0290999 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0289889 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.0289555 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0288488 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0286538 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0285114 |
| NCKAP1 | NCK-associated protein 1 | 0.028303 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0281771 |
| JMJD1C | jumonji domain containing 1C | 0.0277695 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0277168 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0273702 |
| RAI14 | retinoic acid induced 14 | 0.0269549 |
| OPTN | optineurin | 0.026766 |
| SNX9 | sorting nexin 9 | 0.0266382 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0263284 |
| SKIL | SKI-like proto-oncogene | 0.0262743 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0261791 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0261522 |
| TPM4 | tropomyosin 4 | 0.0258739 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0255963 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0255553 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0254942 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0254107 |
| TRIM24 | tripartite motif containing 24 | 0.0253348 |
| TNS3 | tensin 3 | 0.0251622 |
| RPS12 | ribosomal protein S12 | 0.0250658 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0250084 |
| JAK1 | Janus kinase 1 | 0.0250007 |
| ENAH | enabled homolog (Drosophila) | 0.0249361 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0247015 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0244403 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0242019 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0241393 |
| DSTN | destrin (actin depolymerizing factor) | 0.0240495 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0239783 |
| FLNA | filamin A, alpha | 0.0239702 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0239673 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0238393 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0237045 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0236613 |
| GOLGA4 | golgin A4 | 0.0233845 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0229663 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.171621 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.170688 |
| APOB | apolipoprotein B | -0.138424 |
| FN1 | fibronectin 1 | -0.115786 |
| MT2A | metallothionein 2A | -0.0986734 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0978519 |
| TRIM26 | tripartite motif containing 26 | -0.0924808 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0917845 |
| CP | ceruloplasmin (ferroxidase) | -0.0840995 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0784449 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0747071 |
| RRBP1 | ribosome binding protein 1 | -0.0743905 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0734655 |
| FRMD5 | FERM domain containing 5 | -0.0645147 |
| TF | transferrin | -0.0628314 |
| EHBP1 | EH domain binding protein 1 | -0.0621276 |
| GPC3 | glypican 3 | -0.0589459 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0583335 |
| RNF213 | ring finger protein 213 | -0.0581349 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0579198 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0567519 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0560845 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0533404 |
| APOE | apolipoprotein E | -0.0532091 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0517478 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.051082 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0502604 |
| APOA1 | apolipoprotein A-I | -0.0502491 |
| DST | dystonin | -0.0481158 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0478281 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0455455 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0454575 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0450822 |
| TMSB10 | thymosin beta 10 | -0.0446151 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0441257 |
| ATP10A | ATPase, class V, type 10A | -0.0439487 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0438505 |
| FMNL2 | formin-like 2 | -0.0427467 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0412657 |
| AHSG | alpha-2-HS-glycoprotein | -0.0407098 |
| NPR2 | natriuretic peptide receptor 2 | -0.0400415 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0388474 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.038131 |
| H1-0 | H1.0 linker histone | -0.0364261 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0363848 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0363666 |
| APOA2 | apolipoprotein A-II | -0.0357725 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0355173 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0354635 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0354319 |
| NDRG1 | N-myc downstream regulated 1 | -0.0354047 |
| CALD1 | caldesmon 1 | -0.0349649 |
| RPLP1 | ribosomal protein, large, P1 | -0.0344962 |
| CALR | calreticulin | -0.0342229 |
| HMGA2 | high mobility group AT-hook 2 | -0.0341862 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0332958 |
| MATN3 | matrilin 3 | -0.0331429 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0328586 |
| RPL35A | ribosomal protein L35a | -0.0328322 |
| GLG1 | golgi glycoprotein 1 | -0.032369 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.032317 |
| RPL23 | ribosomal protein L23 | -0.0313703 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.0309316 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0307242 |
| STK17A | serine/threonine kinase 17a | -0.0306564 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0306385 |
| EPCAM | epithelial cell adhesion molecule | -0.0301982 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0298405 |
| TMEM123 | transmembrane protein 123 | -0.0297506 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.029312 |
| DOK6 | docking protein 6 | -0.0286327 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0281786 |
| FAM13A | family with sequence similarity 13, member A | -0.0277346 |
| UTRN | utrophin | -0.0276663 |
| GPC6 | glypican 6 | -0.0276232 |
| PHF21A | PHD finger protein 21A | -0.0274875 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0273856 |
| TCF12 | transcription factor 12 | -0.0270689 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0270143 |
| C5 | complement component 5 | -0.0267287 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0266984 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0266938 |
| PEG10 | paternally expressed 10 | -0.026688 |
| FTL | ferritin, light polypeptide | -0.0261212 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0257992 |
| GNAS | GNAS complex locus | -0.0253092 |
| ARF1 | ADP-ribosylation factor 1 | -0.0251342 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0250848 |
| SELENOP | selenoprotein P | -0.0249777 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.024953 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0249158 |
| ZFHX3 | zinc finger homeobox 3 | -0.0248017 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0244773 |
| BPIFB2 | BPI fold containing family B, member 2 | -0.0243409 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0241392 |
| SYN3 | synapsin III | -0.0237338 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.023536 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0234704 |
| CNKSR3 | CNKSR family member 3 | -0.02347 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0232125 |
