| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dihydroartemisinin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHA | lactate dehydrogenase A | 0.192869 |
| RPL3 | ribosomal protein L3 | 0.184143 |
| KRT18 | keratin 18, type I | 0.179875 |
| VEGFA | vascular endothelial growth factor A | 0.142184 |
| RPL13A | ribosomal protein L13a | 0.124457 |
| ITGA6 | integrin, alpha 6 | 0.121438 |
| CANX | calnexin | 0.119398 |
| LMO7 | LIM domain 7 | 0.114784 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.109084 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0841966 |
| AREG | amphiregulin | 0.0779394 |
| FLNB | filamin B, beta | 0.0778153 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0748082 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0718658 |
| HDLBP | high density lipoprotein binding protein | 0.071043 |
| RPL18A | ribosomal protein L18a | 0.0653296 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0640434 |
| APP | amyloid beta (A4) precursor protein | 0.0606002 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0603954 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0603482 |
| FAT1 | FAT atypical cadherin 1 | 0.0565436 |
| DSPP | dentin sialophosphoprotein | 0.0562414 |
| EZR | ezrin | 0.0547784 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0547249 |
| H1-0 | H1.0 linker histone | 0.0536478 |
| ONECUT3 | one cut homeobox 3 | 0.0529706 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0508407 |
| TMSB4X | thymosin beta 4, X-linked | 0.0502294 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.048564 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0485329 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0473191 |
| MYO1E | myosin IE | 0.047041 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0467726 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0454114 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0452032 |
| AHNAK | AHNAK nucleoprotein | 0.0451494 |
| HSPA8 | heat shock 70kDa protein 8 | 0.044861 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0436436 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0430621 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0426544 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0426471 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0426272 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0420938 |
| SET | SET nuclear proto-oncogene | 0.0418754 |
| RPS4X | ribosomal protein S4, X-linked | 0.0416429 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0406358 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.040287 |
| PLEC | plectin | 0.0400827 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0389951 |
| RPL11 | ribosomal protein L11 | 0.038161 |
| NEBL | nebulette | 0.0375986 |
| PIGR | polymeric immunoglobulin receptor | 0.0371721 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0367089 |
| ANXA11 | annexin A11 | 0.036143 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0360686 |
| TPM3 | tropomyosin 3 | 0.0354841 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0352646 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0346054 |
| RPL4 | ribosomal protein L4 | 0.034347 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0341784 |
| LAMB3 | laminin, beta 3 | 0.0328197 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.0327384 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0327146 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0326721 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0324279 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0322669 |
| PCBP2 | poly(rC) binding protein 2 | 0.0321827 |
| CADPS | Ca++-dependent secretion activator | 0.0316827 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0314764 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0313845 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0312466 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.030967 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.030624 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.030219 |
| CPNE1 | copine I | 0.0301371 |
| MCL1 | myeloid cell leukemia 1 | 0.0294402 |
| MYO18A | myosin XVIIIA | 0.0291206 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0287478 |
| DNM2 | dynamin 2 | 0.0285769 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0285022 |
| RBM39 | RNA binding motif protein 39 | 0.0282332 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0282214 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0280556 |
| LAMA4 | laminin, alpha 4 | 0.0279096 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0279004 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0278279 |
| CALR | calreticulin | 0.0277477 |
| MYO5B | myosin VB | 0.0272441 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0272423 |
| HDGF | hepatoma-derived growth factor | 0.0271848 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0271445 |
| YTHDC1 | YTH domain containing 1 | 0.0271258 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0269532 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.02695 |
| SVIL | supervillin | 0.0269382 |
| TPM4 | tropomyosin 4 | 0.0268123 |
| GDF15 | growth differentiation factor 15 | 0.0266335 |
| SQSTM1 | sequestosome 1 | 0.0265755 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0263256 |
| CTBP2 | C-terminal binding protein 2 | 0.0261334 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.258792 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.122606 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0992876 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.090442 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0852015 |
| TMSB10 | thymosin beta 10 | -0.0656408 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0633422 |
| NDRG1 | N-myc downstream regulated 1 | -0.0596557 |
| HMGA1 | high mobility group AT-hook 1 | -0.0547622 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0519428 |
| NPSR1 | neuropeptide S receptor 1 | -0.0430059 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0422605 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0414037 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0382321 |
| POTEF | POTE ankyrin domain family, member F | -0.0380717 |
| TNS4 | tensin 4 | -0.0340153 |
| TXNIP | thioredoxin interacting protein | -0.0340148 |
| GPHN | gephyrin | -0.0339593 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0337597 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.033342 |
| RPL21 | ribosomal protein L21 | -0.0311714 |
| RPL35A | ribosomal protein L35a | -0.0310404 |
| RPLP0 | ribosomal protein, large, P0 | -0.0297488 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0297214 |
| KRT19 | keratin 19, type I | -0.0285103 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0275063 |
| FOSL1 | FOS-like antigen 1 | -0.0265377 |
| PFN1 | profilin 1 | -0.026487 |
| S100A6 | S100 calcium binding protein A6 | -0.026364 |
| RPS6 | ribosomal protein S6 | -0.0261589 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0260442 |
| PERP | PERP, TP53 apoptosis effector | -0.0259467 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0256296 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0254291 |
| ZNF292 | zinc finger protein 292 | -0.0251404 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0247728 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0241734 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0238325 |
| RPS25 | ribosomal protein S25 | -0.0236376 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0235198 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0233149 |
| RPLP2 | ribosomal protein, large, P2 | -0.0231863 |
| S100A10 | S100 calcium binding protein A10 | -0.0231362 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0227007 |
| TUBA1B | tubulin, alpha 1b | -0.0221156 |
| RPS19 | ribosomal protein S19 | -0.0217708 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0212754 |
| MLEC | malectin | -0.0210077 |
| RPL36A | ribosomal protein L36a | -0.0207843 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0203904 |
| RPS24 | ribosomal protein S24 | -0.0202047 |
| ACTG1 | actin gamma 1 | -0.0201712 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0201543 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.019943 |
| INSIG1 | insulin induced gene 1 | -0.0198844 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0196792 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0193123 |
| TMEM123 | transmembrane protein 123 | -0.0189937 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0189337 |
| RPL7A | ribosomal protein L7a | -0.0187311 |
| RYBP | RING1 and YY1 binding protein | -0.0184161 |
| CBX3 | chromobox homolog 3 | -0.0182535 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0181475 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.017727 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0175656 |
| CDC42SE2 | CDC42 small effector 2 | -0.017369 |
| MAGT1 | magnesium transporter 1 | -0.0173626 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0173308 |
| EGR1 | early growth response 1 | -0.0173078 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0171602 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.017143 |
| LYZ | lysozyme | -0.0171393 |
| RPS2 | ribosomal protein S2 | -0.016804 |
| MUC17 | mucin 17, cell surface associated | -0.0167844 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0167599 |
| FHIT | fragile histidine triad | -0.0165182 |
| PHGR1 | proline/histidine/glycine-rich 1 | -0.0163619 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0163349 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0160891 |
| S100A9 | S100 calcium binding protein A9 | -0.0160379 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | -0.0158535 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0156014 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0155875 |
| EXOC1 | exocyst complex component 1 | -0.0155078 |
| FBXO33 | F-box protein 33 | -0.0154751 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | -0.0154294 |
| FERMT1 | fermitin family member 1 | -0.0153231 |
| CCNI | cyclin I | -0.0152206 |
| ATP11B | ATPase, class VI, type 11B | -0.0151291 |
| RPL9 | ribosomal protein L9 | -0.0150332 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0150233 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0149304 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0149069 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0148726 |
| ARF4 | ADP-ribosylation factor 4 | -0.0146864 |
| USP3 | ubiquitin specific peptidase 3 | -0.0146523 |
| CLTC | clathrin, heavy chain (Hc) | -0.0145123 |
| RPL15 | ribosomal protein L15 | -0.0144205 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.014371 |
| CDK6 | cyclin-dependent kinase 6 | -0.0142472 |
