| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL3 | ribosomal protein L3 | 0.0387362 |
| MCL1 | myeloid cell leukemia 1 | 0.0381221 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.038044 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0375602 |
| PLEC | plectin | 0.0367869 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0250554 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0242251 |
| GPC5 | glypican 5 | 0.0230091 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0227277 |
| TOP1 | topoisomerase (DNA) I | 0.0225952 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0217587 |
| RUNX1 | runt-related transcription factor 1 | 0.0209908 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0205281 |
| NABP1 | nucleic acid binding protein 1 | 0.0198523 |
| H1-0 | H1.0 linker histone | 0.019595 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0179878 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0179756 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0176758 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0173661 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0171421 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.016875 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0166379 |
| FNIP1 | folliculin interacting protein 1 | 0.0162623 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0162525 |
| MYO5B | myosin VB | 0.0157652 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0156366 |
| SPAG9 | sperm associated antigen 9 | 0.0151685 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0144696 |
| SLTM | SAFB-like, transcription modulator | 0.014228 |
| NPTN | neuroplastin | 0.013453 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0132351 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0130221 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0126711 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0123758 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0122412 |
| KLC1 | kinesin light chain 1 | 0.0122088 |
| OGA | O-GlcNAcase | 0.0122002 |
| HYOU1 | hypoxia up-regulated 1 | 0.0121065 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0120434 |
| GOLGA3 | golgin A3 | 0.0118379 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0118348 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0117764 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0115947 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0115852 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0114248 |
| SEPTIN10 | septin 10 | 0.0113493 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0112317 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0111959 |
| GAK | cyclin G associated kinase | 0.0109715 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0109086 |
| ATP13A3 | ATPase type 13A3 | 0.0107814 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0107247 |
| PRDM10 | PR domain containing 10 | 0.0106396 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0106161 |
| LINC02210-CRHR1 | LINC02210-CRHR1 readthrough | 0.0105442 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0105284 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0104683 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0104373 |
| DIDO1 | death inducer-obliterator 1 | 0.0104344 |
| CES1 | carboxylesterase 1 | 0.0100779 |
| RPL4 | ribosomal protein L4 | 0.00987474 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.00987387 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.00984557 |
| GPATCH2L | G patch domain containing 2-like | 0.00977424 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00964596 |
| NGLY1 | N-glycanase 1 | 0.00963953 |
| GRB10 | growth factor receptor-bound protein 10 | 0.00963161 |
| YTHDC1 | YTH domain containing 1 | 0.00960439 |
| AGO2 | argonaute RISC catalytic component 2 | 0.00954847 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.009506 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00950147 |
| PMM2 | phosphomannomutase 2 | 0.00947775 |
| RLIM | ring finger protein, LIM domain interacting | 0.00946398 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.00934012 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.00926103 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00915201 |
| CYTH1 | cytohesin 1 | 0.00913962 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00910099 |
| NDE1 | nudE neurodevelopment protein 1 | 0.00906128 |
| ATG7 | autophagy related 7 | 0.00897287 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00883545 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.00881575 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.00878082 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00875544 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00871412 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.00870699 |
| KIAA1217 | KIAA1217 | 0.00870682 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00867366 |
| SFPQ | splicing factor proline/glutamine-rich | 0.00864295 |
| RBM19 | RNA binding motif protein 19 | 0.00859665 |
| CASC3 | cancer susceptibility candidate 3 | 0.00858078 |
| TSPYL2 | TSPY-like 2 | 0.00857145 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00847313 |
| METTL15 | methyltransferase like 15 | 0.00826539 |
| FRY | furry homolog (Drosophila) | 0.00814807 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.00814756 |
| ARRDC3 | arrestin domain containing 3 | 0.00808567 |
| ECT2 | epithelial cell transforming 2 | 0.00808081 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00802056 |
| MYO1B | myosin IB | 0.0079058 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.418007 |
| EGFR | epidermal growth factor receptor | -0.160855 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.118615 |
| TMSB10 | thymosin beta 10 | -0.107664 |
| MT2A | metallothionein 2A | -0.100085 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0815811 |
| NDRG1 | N-myc downstream regulated 1 | -0.080809 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0734845 |
| PKM | pyruvate kinase, muscle | -0.0720203 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0677137 |
| PTMA | prothymosin, alpha | -0.0631204 |
| S100A10 | S100 calcium binding protein A10 | -0.058907 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0543737 |
| ACTG1 | actin gamma 1 | -0.0503894 |
| ENO1 | enolase 1, (alpha) | -0.0497935 |
| FTL | ferritin, light polypeptide | -0.0494241 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0485018 |
| SEC61G | Sec61 gamma subunit | -0.0469781 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0435784 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0435743 |
| STC1 | stanniocalcin 1 | -0.0432336 |
| EGR1 | early growth response 1 | -0.0413577 |
| RPLP1 | ribosomal protein, large, P1 | -0.0397761 |
| LDHA | lactate dehydrogenase A | -0.0394179 |
| MYOF | myoferlin | -0.0390093 |
| CST3 | cystatin C | -0.037571 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0373979 |
| TXNRD1 | thioredoxin reductase 1 | -0.0372428 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0366555 |
| RPL35A | ribosomal protein L35a | -0.0364466 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0353945 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0345445 |
| RPS3 | ribosomal protein S3 | -0.034353 |
| FAM13A | family with sequence similarity 13, member A | -0.0342666 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.033795 |
| ASPH | aspartate beta-hydroxylase | -0.0333602 |
| LMO7 | LIM domain 7 | -0.0328587 |
| CAV2 | caveolin 2 | -0.0328138 |
| B2M | beta-2-microglobulin | -0.0324198 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.032148 |
| RPS25 | ribosomal protein S25 | -0.0320954 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0318014 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0317842 |
| GRAMD1B | GRAM domain containing 1B | -0.0309541 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0304962 |
| FNDC3B | fibronectin type III domain containing 3B | -0.028102 |
| RPS24 | ribosomal protein S24 | -0.0279249 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0273617 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0271436 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0270495 |
| FOXP1 | forkhead box P1 | -0.0269753 |
| RPS6 | ribosomal protein S6 | -0.0269473 |
| RPL37A | ribosomal protein L37a | -0.0261689 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0255367 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0254215 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0252481 |
| LAMA4 | laminin, alpha 4 | -0.0251826 |
| RPL31 | ribosomal protein L31 | -0.0242788 |
| BPTF | bromodomain PHD finger transcription factor | -0.02411 |
| RPS8 | ribosomal protein S8 | -0.0240905 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0238482 |
| RPS12 | ribosomal protein S12 | -0.023692 |
| RPLP0 | ribosomal protein, large, P0 | -0.0232484 |
| S100A11 | S100 calcium binding protein A11 | -0.0231129 |
| RNF213 | ring finger protein 213 | -0.0231065 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0228881 |
| KRT7 | keratin 7, type II | -0.0228471 |
| CPE | carboxypeptidase E | -0.0226811 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.022373 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0223247 |
| ANXA2 | annexin A2 | -0.0221275 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0220671 |
| S100A6 | S100 calcium binding protein A6 | -0.0220121 |
| CDCP1 | CUB domain containing protein 1 | -0.0218599 |
| HLA-B | major histocompatibility complex, class I, B | -0.0218044 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0218007 |
| S100A9 | S100 calcium binding protein A9 | -0.021793 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0214966 |
| CSTB | cystatin B (stefin B) | -0.0214636 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0213651 |
| HMGA1 | high mobility group AT-hook 1 | -0.0211875 |
| RPS27A | ribosomal protein S27a | -0.0208878 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0206549 |
| IER3 | immediate early response 3 | -0.0205769 |
| CCNI | cyclin I | -0.0201145 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0200719 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0200037 |
| CUX1 | cut-like homeobox 1 | -0.0198035 |
| MT1X | metallothionein 1X | -0.0196616 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0196102 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.01961 |
| RPL34 | ribosomal protein L34 | -0.0192221 |
| AREG | amphiregulin | -0.0189844 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0188887 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.018852 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0188122 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.018625 |
| TPI1 | triosephosphate isomerase 1 | -0.0185919 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0184523 |
| S100P | S100 calcium binding protein P | -0.0184245 |
