| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.151353 |
| GRB10 | growth factor receptor-bound protein 10 | 0.092737 |
| VEGFA | vascular endothelial growth factor A | 0.0731595 |
| PCBP2 | poly(rC) binding protein 2 | 0.0730805 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0729868 |
| NAV2 | neuron navigator 2 | 0.0726719 |
| RPL3 | ribosomal protein L3 | 0.0723802 |
| SMAD3 | SMAD family member 3 | 0.071215 |
| CDH13 | cadherin 13 | 0.0669823 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0627767 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0587872 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0568428 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0543277 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0542341 |
| MCL1 | myeloid cell leukemia 1 | 0.0534816 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0532992 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0531764 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0530906 |
| MTSS1 | metastasis suppressor 1 | 0.0525165 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.05198 |
| RAI14 | retinoic acid induced 14 | 0.0513643 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0489847 |
| FN1 | fibronectin 1 | 0.0483818 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0474089 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0468706 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0463263 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0459713 |
| FLNB | filamin B, beta | 0.0453852 |
| LDHA | lactate dehydrogenase A | 0.0442691 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0438066 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0422934 |
| FAM20C | family with sequence similarity 20, member C | 0.0418255 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0406162 |
| GOLGA4 | golgin A4 | 0.0405473 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0402461 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0390399 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0385536 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0359907 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0356884 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0352074 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0350974 |
| OPTN | optineurin | 0.0348402 |
| FAM13A | family with sequence similarity 13, member A | 0.0345181 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0343191 |
| CPNE1 | copine I | 0.0342397 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0334817 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0331214 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0327077 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0326309 |
| GPC6 | glypican 6 | 0.0321526 |
| RUNX2 | runt-related transcription factor 2 | 0.0319023 |
| APP | amyloid beta (A4) precursor protein | 0.0318701 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0314143 |
| FAM107B | family with sequence similarity 107, member B | 0.0309485 |
| SIK3 | SIK family kinase 3 | 0.0307473 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0307147 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0307039 |
| NRP1 | neuropilin 1 | 0.0303629 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0302805 |
| COPA | coatomer protein complex, subunit alpha | 0.0299984 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0299657 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0299123 |
| ANO6 | anoctamin 6 | 0.0298884 |
| SYT1 | synaptotagmin I | 0.0296489 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0292478 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0288751 |
| ATP13A3 | ATPase type 13A3 | 0.0286082 |
| FMNL2 | formin-like 2 | 0.0282233 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0282217 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0281161 |
| THBS1 | thrombospondin 1 | 0.0278249 |
| ANKRD36 | ankyrin repeat domain 36 | 0.027664 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0276447 |
| HMGA2 | high mobility group AT-hook 2 | 0.0272126 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0270342 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0269283 |
| YTHDC1 | YTH domain containing 1 | 0.0268266 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0267416 |
| ADD3 | adducin 3 (gamma) | 0.0266233 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0266122 |
| MEF2A | myocyte enhancer factor 2A | 0.0265242 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0264288 |
| OTUD7B | OTU deubiquitinase 7B | 0.0264096 |
| HDLBP | high density lipoprotein binding protein | 0.0263469 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0256548 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0255917 |
| IL1B | interleukin 1, beta | 0.0254205 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0252746 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0250492 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0249839 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0249753 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0248212 |
| CEP250 | centrosomal protein 250kDa | 0.0248081 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0246722 |
| EFL1 | elongation factor like GTPase 1 | 0.0245887 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0245645 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0241704 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0241589 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0239721 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0239563 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.243883 |
| CD44 | CD44 molecule (Indian blood group) | -0.142183 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.127652 |
| VIM | vimentin | -0.116996 |
| TMSB10 | thymosin beta 10 | -0.107964 |
| LOX | lysyl oxidase | -0.0988744 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0971501 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0793682 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0711953 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0692401 |
| FTL | ferritin, light polypeptide | -0.0682196 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0653114 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.063384 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0631553 |
| OSMR | oncostatin M receptor | -0.0606584 |
| MT2A | metallothionein 2A | -0.0588342 |
| RPLP1 | ribosomal protein, large, P1 | -0.0564495 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0560549 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0553111 |
| PTMA | prothymosin, alpha | -0.0536016 |
| GLCCI1 | glucocorticoid induced 1 | -0.0528975 |
| KYNU | kynureninase | -0.0525815 |
| IER3 | immediate early response 3 | -0.0497154 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0495659 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0486084 |
| EGR1 | early growth response 1 | -0.0434087 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0431178 |
| STC1 | stanniocalcin 1 | -0.0428414 |
| RNF24 | ring finger protein 24 | -0.0418966 |
| RPL35A | ribosomal protein L35a | -0.0407876 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0394677 |
| RPS19 | ribosomal protein S19 | -0.0381734 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0377667 |
| NTN4 | netrin 4 | -0.0368403 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0364255 |
| B2M | beta-2-microglobulin | -0.0336596 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0327608 |
| RPS8 | ribosomal protein S8 | -0.0326177 |
| RPL32 | ribosomal protein L32 | -0.0315656 |
| RPL31 | ribosomal protein L31 | -0.0310255 |
| RPS6 | ribosomal protein S6 | -0.0305617 |
| TNNC1 | troponin C type 1 (slow) | -0.0304918 |
| KSR1 | kinase suppressor of ras 1 | -0.0299616 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0297862 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0296744 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0294901 |
| RPL34 | ribosomal protein L34 | -0.029279 |
| RAD51B | RAD51 paralog B | -0.0290023 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0288874 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0286892 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0286826 |
| RPLP2 | ribosomal protein, large, P2 | -0.0285291 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0284014 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0277306 |
| RPL36 | ribosomal protein L36 | -0.0276449 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0274593 |
| RPS24 | ribosomal protein S24 | -0.0274125 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.026953 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.02667 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0266594 |
| NRG1 | neuregulin 1 | -0.0266578 |
| S100A10 | S100 calcium binding protein A10 | -0.0263092 |
| RPL23 | ribosomal protein L23 | -0.0258947 |
| RPL12 | ribosomal protein L12 | -0.0257967 |
| RPLP0 | ribosomal protein, large, P0 | -0.0256207 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0255272 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0253801 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.024964 |
| RPL28 | ribosomal protein L28 | -0.0248885 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0247878 |
| HMGA1 | high mobility group AT-hook 1 | -0.0242445 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0241088 |
| MX2 | MX dynamin-like GTPase 2 | -0.0240164 |
| ASPH | aspartate beta-hydroxylase | -0.0239472 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0238036 |
| VCL | vinculin | -0.0237044 |
| RPS25 | ribosomal protein S25 | -0.023621 |
| RPS13 | ribosomal protein S13 | -0.023617 |
| RPS21 | ribosomal protein S21 | -0.023355 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0232547 |
| RPS29 | ribosomal protein S29 | -0.0232234 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.023206 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0231524 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0230604 |
| TMEM263 | transmembrane protein 263 | -0.02252 |
| SYAP1 | synapse associated protein 1 | -0.0224561 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0223069 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0222093 |
| CCNI | cyclin I | -0.0221514 |
| RACK1 | receptor for activated C kinase 1 | -0.0221083 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0221059 |
| RPS5 | ribosomal protein S5 | -0.0217819 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.021511 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0213962 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.02129 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0212441 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0211934 |
| S100A6 | S100 calcium binding protein A6 | -0.0211012 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0210554 |
| RPL19 | ribosomal protein L19 | -0.0209118 |
