| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.164074 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.127641 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.11566 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.111503 |
| OGA | O-GlcNAcase | 0.106184 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.105243 |
| CANX | calnexin | 0.0995357 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0988022 |
| LDHA | lactate dehydrogenase A | 0.0924609 |
| MT2A | metallothionein 2A | 0.0912575 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0896089 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0864792 |
| RPS3 | ribosomal protein S3 | 0.0836342 |
| PGK1 | phosphoglycerate kinase 1 | 0.0808949 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0798029 |
| RASA2 | RAS p21 protein activator 2 | 0.0759673 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0753163 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0725939 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0713111 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0699937 |
| PEG10 | paternally expressed 10 | 0.0698401 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0686419 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0679764 |
| FRY | furry homolog (Drosophila) | 0.0658456 |
| RBM39 | RNA binding motif protein 39 | 0.0642322 |
| RREB1 | ras responsive element binding protein 1 | 0.0620918 |
| FAM13A | family with sequence similarity 13, member A | 0.0607724 |
| MATR3 | matrin 3 | 0.060635 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0603591 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0593166 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0589375 |
| NUP58 | nucleoporin 58 | 0.0588357 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0582132 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.058026 |
| IGF2 | insulin-like growth factor 2 | 0.0580151 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0577124 |
| PTK2 | protein tyrosine kinase 2 | 0.0554499 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0546233 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0530339 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0525701 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0521938 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0520761 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0516789 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0511809 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0506423 |
| PRKCA | protein kinase C, alpha | 0.0501928 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0498477 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0484124 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0483484 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0478048 |
| OLA1 | Obg-like ATPase 1 | 0.0477888 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0474602 |
| MYOF | myoferlin | 0.04644 |
| PARD3 | par-3 family cell polarity regulator | 0.0459662 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0454721 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0449274 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0449137 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0443975 |
| PKM | pyruvate kinase, muscle | 0.0441468 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0441005 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0439884 |
| GOLGA4 | golgin A4 | 0.0438973 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0434571 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0425786 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0422352 |
| USP24 | ubiquitin specific peptidase 24 | 0.0420899 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0419551 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0411376 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0396195 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0395984 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0388151 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0385643 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0385592 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0373896 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0363977 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0353828 |
| SLTM | SAFB-like, transcription modulator | 0.0349884 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0347104 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0346212 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0342444 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0332362 |
| YTHDC1 | YTH domain containing 1 | 0.0330144 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0329672 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0314977 |
| MED13L | mediator complex subunit 13-like | 0.0309817 |
| KLF6 | Kruppel-like factor 6 | 0.0308017 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0306164 |
| CCNK | cyclin K | 0.0305797 |
| RPL23 | ribosomal protein L23 | 0.0302668 |
| PUM2 | pumilio RNA-binding family member 2 | 0.030096 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0298307 |
| PLEC | plectin | 0.0292163 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0291962 |
| ETV3 | ets variant 3 | 0.0291899 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0290477 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0289334 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0283625 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.028083 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.028005 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0277382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.244059 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.167963 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.162912 |
| LMO7 | LIM domain 7 | -0.147738 |
| PDE10A | phosphodiesterase 10A | -0.137657 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.132569 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.131569 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.128743 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.119444 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.10707 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.105986 |
| DST | dystonin | -0.103037 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.102067 |
| ZNF638 | zinc finger protein 638 | -0.0972464 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0966717 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0943672 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0934347 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.092224 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0919247 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0882186 |
| RUNX1 | runt-related transcription factor 1 | -0.0879585 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0862373 |
| KYNU | kynureninase | -0.0841248 |
| ASPH | aspartate beta-hydroxylase | -0.0830464 |
| KRT17 | keratin 17, type I | -0.08223 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0793032 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0787554 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0782554 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0778176 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0774363 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0766421 |
| MYO1E | myosin IE | -0.0744025 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0718461 |
| MUC16 | mucin 16, cell surface associated | -0.0716184 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0705639 |
| SVIL | supervillin | -0.0696393 |
| ANXA2 | annexin A2 | -0.0690106 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0664555 |
| GOLGB1 | golgin B1 | -0.0631494 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0626597 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0617267 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0587776 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0585286 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.055495 |
| USP33 | ubiquitin specific peptidase 33 | -0.0553085 |
| INSIG1 | insulin induced gene 1 | -0.0552722 |
| RPS6 | ribosomal protein S6 | -0.0549961 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0547429 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.053791 |
| SEPTIN7 | septin 7 | -0.0523978 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0514553 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0511927 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0504591 |
| JMJD1C | jumonji domain containing 1C | -0.0500017 |
| RPLP1 | ribosomal protein, large, P1 | -0.0496968 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0496671 |
| ANKRD17 | ankyrin repeat domain 17 | -0.04964 |
| VIM | vimentin | -0.049016 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0480057 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0472517 |
| SRPK2 | SRSF protein kinase 2 | -0.0470573 |
| TMSB10 | thymosin beta 10 | -0.0466354 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0443537 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0443099 |
| RTN4 | reticulon 4 | -0.0435718 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0434392 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0375359 |
| TXNRD1 | thioredoxin reductase 1 | -0.0372087 |
| STC1 | stanniocalcin 1 | -0.0368677 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.036417 |
| OSMR | oncostatin M receptor | -0.0364107 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0358809 |
| CMIP | c-Maf inducing protein | -0.0353235 |
| ATOSA | atos homolog A | -0.035163 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0346496 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0336747 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0334551 |
| LAMB3 | laminin, beta 3 | -0.03345 |
| RNF145 | ring finger protein 145 | -0.0329336 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0317381 |
| RPS19 | ribosomal protein S19 | -0.0312629 |
| KIF5B | kinesin family member 5B | -0.027174 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0238205 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.022582 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0211568 |
| ZNF292 | zinc finger protein 292 | -0.0208996 |
| FNIP1 | folliculin interacting protein 1 | -0.0196983 |
| RPS12 | ribosomal protein S12 | -0.0189685 |
| PCBP2 | poly(rC) binding protein 2 | -0.0157293 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0131493 |
| SMYD3 | SET and MYND domain containing 3 | -0.0131471 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0131069 |
| HELZ | helicase with zinc finger | -0.0124805 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.012474 |
| RPL8 | ribosomal protein L8 | -0.012415 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0122463 |
| ACTG1 | actin gamma 1 | -0.0116514 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0110631 |
| MEF2A | myocyte enhancer factor 2A | -0.0100815 |
| NAV3 | neuron navigator 3 | -0.00971746 |
