| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.209378 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0976349 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0801279 |
| GRAMD1B | GRAM domain containing 1B | 0.0696376 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0645814 |
| RTN4 | reticulon 4 | 0.0555425 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0466454 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0430771 |
| XPO1 | exportin 1 | 0.0377679 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0370317 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.036185 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0361553 |
| MSN | moesin | 0.0359198 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0353866 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0343943 |
| RPL3 | ribosomal protein L3 | 0.0335242 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0327879 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0325472 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.031926 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.031906 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0315719 |
| ACTN1 | actinin, alpha 1 | 0.0311519 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.030779 |
| MMP12 | matrix metallopeptidase 12 | 0.0307063 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0305049 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0302995 |
| PLEC | plectin | 0.0300992 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.02976 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0297013 |
| PHIP | pleckstrin homology domain interacting protein | 0.0282994 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0275872 |
| EXOC6B | exocyst complex component 6B | 0.0271508 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.026877 |
| SMAD3 | SMAD family member 3 | 0.0267878 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0266167 |
| RRM2 | ribonucleotide reductase M2 | 0.0261991 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0261311 |
| MED13L | mediator complex subunit 13-like | 0.0258552 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0256836 |
| JMJD1C | jumonji domain containing 1C | 0.0254634 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0254447 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0239287 |
| RASAL2 | RAS protein activator like 2 | 0.023716 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0235041 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0227782 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0224401 |
| EPN2 | epsin 2 | 0.0223857 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0223702 |
| PLCB4 | phospholipase C, beta 4 | 0.0222887 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0221849 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0221317 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0219449 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0218689 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0218384 |
| EXOC4 | exocyst complex component 4 | 0.0217522 |
| DOCK3 | dedicator of cytokinesis 3 | 0.021732 |
| PTK2 | protein tyrosine kinase 2 | 0.0214763 |
| CENPF | centromere protein F, 350/400kDa | 0.0213259 |
| IPO7 | importin 7 | 0.0211725 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0209328 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | 0.0208917 |
| MKI67 | marker of proliferation Ki-67 | 0.0208198 |
| NUP153 | nucleoporin 153kDa | 0.0207504 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0205575 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.020541 |
| GPHN | gephyrin | 0.0205188 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0203661 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0203366 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0201929 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0200664 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0198103 |
| SNX9 | sorting nexin 9 | 0.0197471 |
| SRPK2 | SRSF protein kinase 2 | 0.0196434 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0194835 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0191319 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0190374 |
| DIAPH1 | diaphanous-related formin 1 | 0.0189315 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0189104 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0188154 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0188025 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0186763 |
| RAI1 | retinoic acid induced 1 | 0.0186498 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0186023 |
| MYPN | myopalladin | 0.0185212 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0185208 |
| MELK | maternal embryonic leucine zipper kinase | 0.0184465 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0183676 |
| RFX7 | regulatory factor X, 7 | 0.0183481 |
| MAP4 | microtubule-associated protein 4 | 0.0183378 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0182492 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0181827 |
| NOTCH2 | notch 2 | 0.0179178 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0179175 |
| NCKAP1 | NCK-associated protein 1 | 0.0178361 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0177764 |
| ATXN2 | ataxin 2 | 0.0177726 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0175448 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0175353 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0174779 |
| TMEM41B | transmembrane protein 41B | 0.0172323 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.220122 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127073 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.115067 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.114338 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.104816 |
| TMSB10 | thymosin beta 10 | -0.0681672 |
| PTMA | prothymosin, alpha | -0.0644576 |
| CANX | calnexin | -0.063435 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0586061 |
| RPS8 | ribosomal protein S8 | -0.0471206 |
| CALR | calreticulin | -0.0463203 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0432569 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0427757 |
| AEBP2 | AE binding protein 2 | -0.0427061 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0413089 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0408079 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0403892 |
| RYR3 | ryanodine receptor 3 | -0.0394968 |
| PDE10A | phosphodiesterase 10A | -0.0392508 |
| RPL23 | ribosomal protein L23 | -0.037921 |
| RPL37A | ribosomal protein L37a | -0.0376428 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0374392 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0362347 |
| RPLP1 | ribosomal protein, large, P1 | -0.0359571 |
| RPL37 | ribosomal protein L37 | -0.0355228 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0353566 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0353199 |
| RPS21 | ribosomal protein S21 | -0.0352898 |
| EGR1 | early growth response 1 | -0.0351343 |
| PRELID2 | PRELI domain containing 2 | -0.0351162 |
| HMGA2 | high mobility group AT-hook 2 | -0.0345606 |
| RPS12 | ribosomal protein S12 | -0.0344604 |
| FMNL2 | formin-like 2 | -0.0335898 |
| TPI1 | triosephosphate isomerase 1 | -0.03348 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0316137 |
| RPS3 | ribosomal protein S3 | -0.0315895 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0313894 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0313688 |
| INTS6 | integrator complex subunit 6 | -0.0309072 |
| RPS27 | ribosomal protein S27 | -0.0305933 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0305905 |
| GNAS | GNAS complex locus | -0.0305786 |
| RPL12 | ribosomal protein L12 | -0.0301569 |
| RPL35A | ribosomal protein L35a | -0.0298603 |
| RPS19 | ribosomal protein S19 | -0.029827 |
| RPL26 | ribosomal protein L26 | -0.0295464 |
| VCL | vinculin | -0.0295115 |
| HLA-B | major histocompatibility complex, class I, B | -0.0287326 |
| YBX3 | Y box binding protein 3 | -0.0285835 |
| RPL13A | ribosomal protein L13a | -0.0279253 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0277387 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0277194 |
| RPL19 | ribosomal protein L19 | -0.0276879 |
| RPL8 | ribosomal protein L8 | -0.0274963 |
| KRT18 | keratin 18, type I | -0.0274696 |
| RPL36 | ribosomal protein L36 | -0.0269292 |
| RPL38 | ribosomal protein L38 | -0.0267679 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0267045 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0264634 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0263468 |
| YBX1 | Y box binding protein 1 | -0.025865 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0258194 |
| RPS4X | ribosomal protein S4, X-linked | -0.0251696 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0250819 |
| RPL35 | ribosomal protein L35 | -0.0250334 |
| TPM2 | tropomyosin 2 (beta) | -0.0248928 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0247069 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0245138 |
| RACK1 | receptor for activated C kinase 1 | -0.0243898 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0241642 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0236264 |
| NEK10 | NIMA-related kinase 10 | -0.0235071 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0233267 |
| RBM39 | RNA binding motif protein 39 | -0.0231501 |
| RPL11 | ribosomal protein L11 | -0.0231451 |
| RPS29 | ribosomal protein S29 | -0.0231217 |
| FTL | ferritin, light polypeptide | -0.0229893 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0228521 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0228022 |
| RPL31 | ribosomal protein L31 | -0.022797 |
| RPS27A | ribosomal protein S27a | -0.0227533 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0225758 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0224025 |
| ACTG1 | actin gamma 1 | -0.0216347 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0214905 |
| MORF4L2 | mortality factor 4 like 2 | -0.0210952 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0210576 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0209999 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0208473 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0207177 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0206585 |
| LRRC23 | leucine rich repeat containing 23 | -0.0206043 |
| WWOX | WW domain containing oxidoreductase | -0.0204944 |
| VIM | vimentin | -0.020286 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0202635 |
| PFN1 | profilin 1 | -0.0200011 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0195174 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0188747 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0187324 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0186596 |
