| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.211695 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.106394 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.102504 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0854145 |
| PLEC | plectin | 0.0815912 |
| RPL3 | ribosomal protein L3 | 0.0749063 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0736557 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.072086 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0697552 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0667617 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0637688 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0637447 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0629245 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0590175 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0589888 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0573341 |
| RBM39 | RNA binding motif protein 39 | 0.0567192 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0564475 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0561583 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0559652 |
| HSPA8 | heat shock 70kDa protein 8 | 0.054334 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0532505 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0530758 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0528917 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0507259 |
| RPL4 | ribosomal protein L4 | 0.0486724 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0483159 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0477858 |
| ZNF292 | zinc finger protein 292 | 0.0477674 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0476561 |
| LDHA | lactate dehydrogenase A | 0.0470475 |
| USP3 | ubiquitin specific peptidase 3 | 0.0469788 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0465982 |
| YTHDC1 | YTH domain containing 1 | 0.0457494 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0456064 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0440738 |
| PAPOLA | poly(A) polymerase alpha | 0.0437815 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.043775 |
| MEF2A | myocyte enhancer factor 2A | 0.043366 |
| CDC73 | cell division cycle 73 | 0.0423515 |
| SPAG9 | sperm associated antigen 9 | 0.0410994 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0407913 |
| APP | amyloid beta (A4) precursor protein | 0.0404563 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0396271 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0395841 |
| RNF145 | ring finger protein 145 | 0.0390555 |
| PCBP2 | poly(rC) binding protein 2 | 0.0376246 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0373166 |
| PTK2 | protein tyrosine kinase 2 | 0.0372218 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0370915 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0369888 |
| CCNL1 | cyclin L1 | 0.0364965 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0362605 |
| FLNA | filamin A, alpha | 0.0351048 |
| NPTN | neuroplastin | 0.0349909 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0348582 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0347826 |
| FAM13A | family with sequence similarity 13, member A | 0.0344059 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0343984 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0341695 |
| RBM33 | RNA binding motif protein 33 | 0.0330602 |
| CANX | calnexin | 0.0330137 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0329763 |
| LAMC2 | laminin, gamma 2 | 0.0326989 |
| NCKAP1 | NCK-associated protein 1 | 0.0325145 |
| MCL1 | myeloid cell leukemia 1 | 0.0320625 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0318984 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0316282 |
| PLAU | plasminogen activator, urokinase | 0.0315696 |
| TOP1 | topoisomerase (DNA) I | 0.0315097 |
| CDK17 | cyclin-dependent kinase 17 | 0.0313114 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0311949 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0307698 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0306941 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0306802 |
| RPL13A | ribosomal protein L13a | 0.0304752 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0304447 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0303255 |
| IRF6 | interferon regulatory factor 6 | 0.0299869 |
| TUFT1 | tuftelin 1 | 0.0297017 |
| QKI | QKI, KH domain containing, RNA binding | 0.0296761 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0292658 |
| UPP1 | uridine phosphorylase 1 | 0.0292226 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0289346 |
| MATR3 | matrin 3 | 0.0287731 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0283396 |
| MYO5B | myosin VB | 0.0283209 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0281449 |
| SET | SET nuclear proto-oncogene | 0.0280683 |
| LAMB3 | laminin, beta 3 | 0.0279748 |
| DUSP10 | dual specificity phosphatase 10 | 0.0278354 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0276091 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0274912 |
| G0S2 | G0/G1 switch 2 | 0.0274806 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0272152 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0269637 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0266141 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0265059 |
| MTMR3 | myotubularin related protein 3 | 0.0262339 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0261803 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.24098 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.215893 |
| TMSB10 | thymosin beta 10 | -0.13828 |
| POTEF | POTE ankyrin domain family, member F | -0.121636 |
| S100A6 | S100 calcium binding protein A6 | -0.105821 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.102748 |
| ACTG1 | actin gamma 1 | -0.100277 |
| FTL | ferritin, light polypeptide | -0.0988067 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0761407 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0708571 |
| PTMA | prothymosin, alpha | -0.068765 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.065893 |
| EFNA5 | ephrin-A5 | -0.0658863 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.064643 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0586219 |
| CSTB | cystatin B (stefin B) | -0.0549383 |
| FBXO32 | F-box protein 32 | -0.054425 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0541114 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0537541 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0516574 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0506074 |
| TXNIP | thioredoxin interacting protein | -0.0497536 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0497144 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0488288 |
| ENO1 | enolase 1, (alpha) | -0.0480035 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.047616 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0445173 |
| LMO7 | LIM domain 7 | -0.0444457 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0444444 |
| S100A10 | S100 calcium binding protein A10 | -0.0444268 |
| MT2A | metallothionein 2A | -0.0438868 |
| KRT19 | keratin 19, type I | -0.0424546 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0418509 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.041422 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0409735 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0405357 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0398799 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.038976 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0384533 |
| LMNA | lamin A/C | -0.0379057 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.035727 |
| HMGA1 | high mobility group AT-hook 1 | -0.0344475 |
| S100A9 | S100 calcium binding protein A9 | -0.0342802 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0336827 |
| CCND1 | cyclin D1 | -0.0334126 |
| TMSB4X | thymosin beta 4, X-linked | -0.0329744 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0328553 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0325758 |
| TMEM165 | transmembrane protein 165 | -0.0315334 |
| HLA-B | major histocompatibility complex, class I, B | -0.0311852 |
| RAI14 | retinoic acid induced 14 | -0.030263 |
| VIM | vimentin | -0.0301924 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.029822 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0295276 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0291789 |
| ATXN1 | ataxin 1 | -0.0284991 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0284399 |
| RPLP2 | ribosomal protein, large, P2 | -0.0284266 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0284201 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0284066 |
| MX2 | MX dynamin-like GTPase 2 | -0.0282067 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0280533 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0280418 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0278154 |
| TPI1 | triosephosphate isomerase 1 | -0.0277147 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0276436 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0274631 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0274014 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0273497 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0271993 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0271121 |
| RRBP1 | ribosome binding protein 1 | -0.0268463 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0263778 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0263337 |
| KRT7 | keratin 7, type II | -0.0257596 |
| RAD51B | RAD51 paralog B | -0.0255067 |
| MYO6 | myosin VI | -0.025394 |
| FRMD5 | FERM domain containing 5 | -0.0244553 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0241471 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0241185 |
| NDRG1 | N-myc downstream regulated 1 | -0.0240635 |
| HLA-A | major histocompatibility complex, class I, A | -0.0235666 |
| CD63 | CD63 molecule | -0.0233771 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0231335 |
| CLDN4 | claudin 4 | -0.0229457 |
| SVIL | supervillin | -0.0228572 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0223744 |
| CCNI | cyclin I | -0.0223732 |
| IFI44L | interferon-induced protein 44-like | -0.0221256 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.022085 |
| MYO1E | myosin IE | -0.0220844 |
| SNX6 | sorting nexin 6 | -0.0218955 |
| CD2AP | CD2-associated protein | -0.0218562 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.021798 |
| DUSP6 | dual specificity phosphatase 6 | -0.0216238 |
| RPS19 | ribosomal protein S19 | -0.0215796 |
| RBM47 | RNA binding motif protein 47 | -0.0210932 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0210825 |
| JUP | junction plakoglobin | -0.0210301 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0210143 |
