| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | 0.135438 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.116897 |
| FN1 | fibronectin 1 | 0.105984 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0968757 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0840356 |
| RPL3 | ribosomal protein L3 | 0.0770496 |
| CANX | calnexin | 0.064232 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0607013 |
| LDHA | lactate dehydrogenase A | 0.0596875 |
| STC1 | stanniocalcin 1 | 0.0517261 |
| VIM | vimentin | 0.048356 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0454148 |
| GDA | guanine deaminase | 0.0446029 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0439257 |
| MYOF | myoferlin | 0.0428053 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0426967 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0416053 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0401908 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0399873 |
| IL6 | interleukin 6 | 0.038004 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0361786 |
| AUTS2 | autism susceptibility candidate 2 | 0.0359453 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0354035 |
| FLNB | filamin B, beta | 0.0353135 |
| NBEAL1 | neurobeachin-like 1 | 0.0348993 |
| FMNL2 | formin-like 2 | 0.0341733 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0336396 |
| PYGL | phosphorylase, glycogen, liver | 0.0336052 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0335002 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0332229 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0330388 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0326316 |
| NDRG1 | N-myc downstream regulated 1 | 0.0325406 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0324448 |
| CHL1 | cell adhesion molecule L1-like | 0.0324385 |
| INHBA | inhibin, beta A | 0.0319273 |
| HLA-A | major histocompatibility complex, class I, A | 0.031086 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0303436 |
| PCBP2 | poly(rC) binding protein 2 | 0.029223 |
| COPA | coatomer protein complex, subunit alpha | 0.0291592 |
| MSN | moesin | 0.0288204 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0285826 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0279276 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0276761 |
| DNER | delta/notch-like EGF repeat containing | 0.0274003 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0270805 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0270457 |
| MAP7 | microtubule-associated protein 7 | 0.0267402 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0267004 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0262923 |
| HDAC4 | histone deacetylase 4 | 0.0261562 |
| STC2 | stanniocalcin 2 | 0.0258315 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0256351 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0250515 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0249184 |
| CTBP2 | C-terminal binding protein 2 | 0.0247842 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0243417 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0241172 |
| FNIP1 | folliculin interacting protein 1 | 0.0236597 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0233875 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0230604 |
| CTSL | cathepsin L | 0.0229352 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0229174 |
| ZNF638 | zinc finger protein 638 | 0.0228921 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0228631 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0226067 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0222759 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0220431 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.022012 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0216538 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0215736 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0215656 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0210658 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0202317 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0199073 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0198849 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0198723 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0198706 |
| TPM4 | tropomyosin 4 | 0.0196008 |
| PRKCA | protein kinase C, alpha | 0.0192848 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0192448 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0191785 |
| KIF16B | kinesin family member 16B | 0.0191283 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0191062 |
| INSIG2 | insulin induced gene 2 | 0.0191015 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0189914 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0189025 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.018847 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0187536 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0187217 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0185833 |
| PCBP3 | poly(rC) binding protein 3 | 0.0184952 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0182567 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.01811 |
| XYLT1 | xylosyltransferase I | 0.0180429 |
| CD99 | CD99 molecule | 0.0179982 |
| CA12 | carbonic anhydrase XII | 0.0178694 |
| DENND1A | DENN/MADD domain containing 1A | 0.0176012 |
| RCOR1 | REST corepressor 1 | 0.0175686 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0174065 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.171822 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.150879 |
| EFNA5 | ephrin-A5 | -0.127426 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113306 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0966533 |
| TXNRD1 | thioredoxin reductase 1 | -0.083434 |
| TMSB10 | thymosin beta 10 | -0.0783399 |
| ASPH | aspartate beta-hydroxylase | -0.075372 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0641093 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0564955 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0511041 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.050538 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0488095 |
| SMYD3 | SET and MYND domain containing 3 | -0.0483184 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0448948 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.043565 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0434672 |
| RPS24 | ribosomal protein S24 | -0.0426173 |
| NRCAM | neuronal cell adhesion molecule | -0.0423752 |
| COL5A2 | collagen, type V, alpha 2 | -0.0421676 |
| PDE10A | phosphodiesterase 10A | -0.0412585 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0409845 |
| TNPO1 | transportin 1 | -0.0397274 |
| NEK7 | NIMA-related kinase 7 | -0.0396799 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0383371 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0376239 |
| RTN4 | reticulon 4 | -0.0368045 |
| RPLP1 | ribosomal protein, large, P1 | -0.0352609 |
| ACTG1 | actin gamma 1 | -0.0335563 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0329309 |
| RPL26 | ribosomal protein L26 | -0.0318199 |
| RPL23 | ribosomal protein L23 | -0.031622 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0311198 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0308477 |
| ENAH | enabled homolog (Drosophila) | -0.0305767 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0303309 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0292147 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0290226 |
| RPS21 | ribosomal protein S21 | -0.0282575 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0277757 |
| RPL35A | ribosomal protein L35a | -0.0270491 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0266546 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.026641 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0263292 |
| RPL34 | ribosomal protein L34 | -0.0253965 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.025107 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0248491 |
| RPL12 | ribosomal protein L12 | -0.0244952 |
| RPS8 | ribosomal protein S8 | -0.0244118 |
| CENPF | centromere protein F, 350/400kDa | -0.0243048 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0242893 |
| CTSC | cathepsin C | -0.023962 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0237799 |
| PALLD | palladin, cytoskeletal associated protein | -0.0227346 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0226916 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0226243 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0225781 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0225157 |
| JMJD1C | jumonji domain containing 1C | -0.0221987 |
| RPLP2 | ribosomal protein, large, P2 | -0.0221308 |
| DIAPH3 | diaphanous-related formin 3 | -0.0220386 |
| MAP1B | microtubule-associated protein 1B | -0.0219155 |
| PRDX1 | peroxiredoxin 1 | -0.0213813 |
| CDK6 | cyclin-dependent kinase 6 | -0.0212101 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0206303 |
| WDR43 | WD repeat domain 43 | -0.020581 |
| OLA1 | Obg-like ATPase 1 | -0.020498 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0204816 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0204109 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0203559 |
| NOP58 | NOP58 ribonucleoprotein | -0.020097 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0199523 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0198413 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0198139 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0197381 |
| RPL35 | ribosomal protein L35 | -0.01964 |
| ANTXR1 | anthrax toxin receptor 1 | -0.019534 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0195225 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0194664 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0194295 |
| RPL38 | ribosomal protein L38 | -0.0194291 |
| ANLN | anillin, actin binding protein | -0.0193694 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0192186 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0190443 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0189401 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0187095 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0186435 |
| CDH13 | cadherin 13 | -0.0186434 |
| HMGB1 | high mobility group box 1 | -0.0183528 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0183182 |
| CREB5 | cAMP responsive element binding protein 5 | -0.018162 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0181552 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0179901 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0179382 |
| RPS6 | ribosomal protein S6 | -0.0179082 |
| RGS2 | regulator of G-protein signaling 2 | -0.0179049 |
| RPS2 | ribosomal protein S2 | -0.0178691 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0175145 |
| TCF12 | transcription factor 12 | -0.0175038 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0174759 |
