| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL3 | ribosomal protein L3 | 0.120183 |
| SPAG9 | sperm associated antigen 9 | 0.104027 |
| TSC22D2 | TSC22 domain family, member 2 | 0.100428 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0925938 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0913575 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0778335 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0728458 |
| FNDC3B | fibronectin type III domain containing 3B | 0.070403 |
| THBS1 | thrombospondin 1 | 0.0694855 |
| HDAC9 | histone deacetylase 9 | 0.0688234 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0687188 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0672432 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0668614 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0659625 |
| APP | amyloid beta (A4) precursor protein | 0.0647835 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0619232 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.060246 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0594654 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0590672 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0574504 |
| CANX | calnexin | 0.0574453 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0570291 |
| SETD5 | SET domain containing 5 | 0.0561383 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0551031 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0541877 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0534816 |
| LDHA | lactate dehydrogenase A | 0.053084 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0528716 |
| JMJD1C | jumonji domain containing 1C | 0.0522665 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0512592 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0509486 |
| SRP54 | signal recognition particle 54kDa | 0.0498903 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0494416 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0493618 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0478279 |
| ZNF217 | zinc finger protein 217 | 0.0475476 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0475069 |
| RBM39 | RNA binding motif protein 39 | 0.047368 |
| UPP1 | uridine phosphorylase 1 | 0.0466481 |
| PCBP2 | poly(rC) binding protein 2 | 0.0465302 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0462784 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0459886 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0442743 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0440992 |
| CALR | calreticulin | 0.0435902 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0429141 |
| NCKAP1 | NCK-associated protein 1 | 0.0426921 |
| ZNF292 | zinc finger protein 292 | 0.0425637 |
| ENAH | enabled homolog (Drosophila) | 0.0422931 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0421734 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0420541 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0418944 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0411946 |
| STAG2 | stromal antigen 2 | 0.0409157 |
| TPM3 | tropomyosin 3 | 0.040674 |
| PDS5B | PDS5 cohesin associated factor B | 0.0405923 |
| MEMO1 | mediator of cell motility 1 | 0.0398794 |
| MYO10 | myosin X | 0.0398616 |
| SET | SET nuclear proto-oncogene | 0.0393523 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0387246 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0379505 |
| CDC14A | cell division cycle 14A | 0.0372735 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0367043 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0364566 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0362003 |
| MB21D2 | Mab-21 domain containing 2 | 0.0360837 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0357878 |
| TCP1 | t-complex 1 | 0.0356574 |
| RBM33 | RNA binding motif protein 33 | 0.0355919 |
| MED13L | mediator complex subunit 13-like | 0.0352988 |
| BRD2 | bromodomain containing 2 | 0.0348989 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0343979 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0342993 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0341709 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0341502 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0339632 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.033834 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0332626 |
| CDC73 | cell division cycle 73 | 0.0329649 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0328593 |
| ITGAV | integrin, alpha V | 0.0328322 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0327564 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0324735 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0323512 |
| SYT1 | synaptotagmin I | 0.0322784 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0318875 |
| CCNL1 | cyclin L1 | 0.0318508 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0318092 |
| FAM171B | family with sequence similarity 171, member B | 0.0315345 |
| NONO | non-POU domain containing, octamer-binding | 0.0314987 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0314802 |
| MCL1 | myeloid cell leukemia 1 | 0.0312717 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.031067 |
| XPO1 | exportin 1 | 0.0308574 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0307583 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0305375 |
| FNBP1L | formin binding protein 1-like | 0.0304781 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0304738 |
| WDR43 | WD repeat domain 43 | 0.0301638 |
| RANBP9 | RAN binding protein 9 | 0.030142 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.117687 |
| VIM | vimentin | -0.115016 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.113229 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.103559 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0965263 |
| ACTG1 | actin gamma 1 | -0.0942052 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0822577 |
| PCDH9 | protocadherin 9 | -0.0788912 |
| FOXP2 | forkhead box P2 | -0.0781086 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0779365 |
| TMSB10 | thymosin beta 10 | -0.0771887 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0725371 |
| TENM3 | teneurin transmembrane protein 3 | -0.0632044 |
| MEIS2 | Meis homeobox 2 | -0.0581448 |
| RPLP1 | ribosomal protein, large, P1 | -0.0527817 |
| RPS16 | ribosomal protein S16 | -0.0507682 |
| PEG10 | paternally expressed 10 | -0.0496276 |
| GPC3 | glypican 3 | -0.0491097 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0477854 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0452304 |
| PFN1 | profilin 1 | -0.0433419 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0429835 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0428764 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0396844 |
| SMYD3 | SET and MYND domain containing 3 | -0.039612 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0395336 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0362904 |
| AK1 | adenylate kinase 1 | -0.0360407 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.035082 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0341427 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0334946 |
| HMGA2 | high mobility group AT-hook 2 | -0.0333433 |
| RAD51B | RAD51 paralog B | -0.0326164 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0317347 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0313403 |
| RPS8 | ribosomal protein S8 | -0.0305296 |
| RPS24 | ribosomal protein S24 | -0.0301377 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0291261 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0290836 |
| PRKD1 | protein kinase D1 | -0.029057 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0288553 |
| SNX6 | sorting nexin 6 | -0.0280006 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.027405 |
| RPS19 | ribosomal protein S19 | -0.027326 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0272619 |
| ZNF385D | zinc finger protein 385D | -0.0264876 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0261491 |
| COL5A2 | collagen, type V, alpha 2 | -0.0258897 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0258886 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0255695 |
| HMGB1 | high mobility group box 1 | -0.0255103 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0252804 |
| BPTF | bromodomain PHD finger transcription factor | -0.025277 |
| RPL35A | ribosomal protein L35a | -0.0251563 |
| RPS21 | ribosomal protein S21 | -0.0248773 |
| DMD | dystrophin | -0.024656 |
| RPLP0 | ribosomal protein, large, P0 | -0.0245825 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0245114 |
| TMEM165 | transmembrane protein 165 | -0.0242121 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0241813 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0241344 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0240849 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0240446 |
| RPS2 | ribosomal protein S2 | -0.0237458 |
| CDK12 | cyclin-dependent kinase 12 | -0.0234095 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0231161 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0228309 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0227645 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0227054 |
| RPL34 | ribosomal protein L34 | -0.022626 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0223093 |
| SGO2 | shugoshin 2 | -0.0222874 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0222187 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0220297 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0217546 |
| RPL30 | ribosomal protein L30 | -0.0216013 |
| GPATCH8 | G patch domain containing 8 | -0.021419 |
| RPS6 | ribosomal protein S6 | -0.0213743 |
| PCYOX1 | prenylcysteine oxidase 1 | -0.0211079 |
| ZNF638 | zinc finger protein 638 | -0.0207061 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0206098 |
| RPL38 | ribosomal protein L38 | -0.0205997 |
| METAP2 | methionyl aminopeptidase 2 | -0.0205861 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0205499 |
| VCL | vinculin | -0.0203416 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0202384 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0202175 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0202051 |
| RACK1 | receptor for activated C kinase 1 | -0.0201709 |
| RPL31 | ribosomal protein L31 | -0.0201185 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0199477 |
| POU3F2 | POU class 3 homeobox 2 | -0.0198985 |
| PRELID2 | PRELI domain containing 2 | -0.0198847 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0198402 |
| WDR70 | WD repeat domain 70 | -0.0198137 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0197894 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | -0.0197717 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0197012 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.019654 |
| CDH19 | cadherin 19, type 2 | -0.0196346 |
