| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.15071 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.123729 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.11728 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0977824 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0890022 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0836603 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0821718 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0720914 |
| FN1 | fibronectin 1 | 0.0712587 |
| VEGFA | vascular endothelial growth factor A | 0.066154 |
| LDHA | lactate dehydrogenase A | 0.0658584 |
| PCBP2 | poly(rC) binding protein 2 | 0.0648218 |
| OGA | O-GlcNAcase | 0.0598673 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0581962 |
| FLNA | filamin A, alpha | 0.0571634 |
| MSN | moesin | 0.0545198 |
| ARRDC3 | arrestin domain containing 3 | 0.0528228 |
| RPL3 | ribosomal protein L3 | 0.0504793 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0460429 |
| RPS4X | ribosomal protein S4, X-linked | 0.0436359 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0415943 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0402929 |
| GOLGA4 | golgin A4 | 0.0399547 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0390525 |
| DIAPH3 | diaphanous-related formin 3 | 0.0372161 |
| SPAG9 | sperm associated antigen 9 | 0.0370727 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0369452 |
| CCNL1 | cyclin L1 | 0.0367771 |
| MKI67 | marker of proliferation Ki-67 | 0.0361294 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0350381 |
| FLNB | filamin B, beta | 0.034464 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0339927 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0337986 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0333767 |
| ANLN | anillin, actin binding protein | 0.0333723 |
| OPTN | optineurin | 0.0325285 |
| TXNIP | thioredoxin interacting protein | 0.0325128 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0307541 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0301542 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0299247 |
| SFTPA2 | surfactant protein A2 | 0.0296965 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0290404 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0282918 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0280273 |
| PHIP | pleckstrin homology domain interacting protein | 0.0270037 |
| ZNF292 | zinc finger protein 292 | 0.0267866 |
| MYOF | myoferlin | 0.026204 |
| APP | amyloid beta (A4) precursor protein | 0.0261333 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0260781 |
| RBM39 | RNA binding motif protein 39 | 0.0257905 |
| CPNE1 | copine I | 0.025679 |
| DSTN | destrin (actin depolymerizing factor) | 0.0253449 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0253047 |
| HELZ | helicase with zinc finger | 0.0251364 |
| TXNRD1 | thioredoxin reductase 1 | 0.0250632 |
| ADAR | adenosine deaminase, RNA-specific | 0.0249318 |
| TPX2 | TPX2, microtubule-associated | 0.0248794 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0248552 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0248219 |
| TPM3 | tropomyosin 3 | 0.0247388 |
| CANX | calnexin | 0.0245334 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0243568 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0243496 |
| CEP250 | centrosomal protein 250kDa | 0.0241809 |
| SET | SET nuclear proto-oncogene | 0.0240573 |
| SDC4 | syndecan 4 | 0.0239933 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0239037 |
| KIF4A | kinesin family member 4A | 0.023781 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0236278 |
| CENPF | centromere protein F, 350/400kDa | 0.0235861 |
| NONO | non-POU domain containing, octamer-binding | 0.0235758 |
| YBX1 | Y box binding protein 1 | 0.0230768 |
| YTHDC1 | YTH domain containing 1 | 0.0228863 |
| MATR3 | matrin 3 | 0.0228244 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0225492 |
| WTAP | Wilms tumor 1 associated protein | 0.0224598 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0224221 |
| SERINC1 | serine incorporator 1 | 0.0221676 |
| RTN4 | reticulon 4 | 0.0221007 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0212664 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0210767 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0209685 |
| TMEM123 | transmembrane protein 123 | 0.0207435 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0205518 |
| SRP54 | signal recognition particle 54kDa | 0.0205225 |
| VCL | vinculin | 0.0203993 |
| SETD5 | SET domain containing 5 | 0.0201685 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0201227 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0201171 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0198068 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0197866 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0196932 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0195359 |
| THOC2 | THO complex 2 | 0.0193267 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0192782 |
| AHR | aryl hydrocarbon receptor | 0.0191803 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0191575 |
| TUBB | tubulin, beta class I | 0.0191339 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0190275 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0189089 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.191601 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.145405 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.132661 |
| GLIS3 | GLIS family zinc finger 3 | -0.117871 |
| IER3 | immediate early response 3 | -0.112457 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.109191 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0914329 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0889715 |
| CDH13 | cadherin 13 | -0.086162 |
| FRMD4A | FERM domain containing 4A | -0.0832114 |
| HLA-B | major histocompatibility complex, class I, B | -0.0819238 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0799501 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0766026 |
| HMGA2 | high mobility group AT-hook 2 | -0.0758195 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0751602 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0718879 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0703813 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0691948 |
| CD44 | CD44 molecule (Indian blood group) | -0.0661441 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0654463 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.063299 |
| TMSB10 | thymosin beta 10 | -0.0574045 |
| RAI14 | retinoic acid induced 14 | -0.0562802 |
| EGFR | epidermal growth factor receptor | -0.0558227 |
| PDE10A | phosphodiesterase 10A | -0.0554375 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.051733 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.051386 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0509516 |
| ASPH | aspartate beta-hydroxylase | -0.0504775 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0480976 |
| DIAPH2 | diaphanous-related formin 2 | -0.0463125 |
| TMEM132D | transmembrane protein 132D | -0.0456611 |
| LOX | lysyl oxidase | -0.0456136 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0453672 |
| TMSB4X | thymosin beta 4, X-linked | -0.0438627 |
| EFNA5 | ephrin-A5 | -0.0437316 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0433184 |
| NAV1 | neuron navigator 1 | -0.043273 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0430008 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0423286 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0386443 |
| ENO1 | enolase 1, (alpha) | -0.0365829 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0365512 |
| CLMP | CXADR-like membrane protein | -0.0363925 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.035727 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0355227 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0354117 |
| VCAN | versican | -0.0348972 |
| INHBA | inhibin, beta A | -0.0337282 |
| HLA-E | major histocompatibility complex, class I, E | -0.0331171 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0328573 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0317997 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0316074 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0309702 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0302761 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0302559 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.029613 |
| FTL | ferritin, light polypeptide | -0.0292626 |
| RRBP1 | ribosome binding protein 1 | -0.0291587 |
| COL5A1 | collagen, type V, alpha 1 | -0.0289153 |
| GPC6 | glypican 6 | -0.0288605 |
| MT2A | metallothionein 2A | -0.0285298 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0283112 |
| DST | dystonin | -0.0282464 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.02818 |
| MMP12 | matrix metallopeptidase 12 | -0.0273958 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0273526 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0272384 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0271182 |
| NRN1 | neuritin 1 | -0.0270459 |
| HLA-A | major histocompatibility complex, class I, A | -0.0269409 |
| STC1 | stanniocalcin 1 | -0.0263422 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0257989 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0252844 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0252305 |
| CTSD | cathepsin D | -0.0250944 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0248912 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0247581 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0240527 |
| WFDC10B | WAP four-disulfide core domain 10B | -0.023988 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0239045 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0238584 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0238264 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0236355 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0232834 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0229927 |
| TNS3 | tensin 3 | -0.0227868 |
| BNC2 | basonuclin 2 | -0.0225347 |
| KRT19 | keratin 19, type I | -0.0223904 |
| LSAMP | limbic system-associated membrane protein | -0.0221285 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0221048 |
| SCGB1D1 | secretoglobin, family 1D, member 1 | -0.0220192 |
| SMYD3 | SET and MYND domain containing 3 | -0.0218909 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0218883 |
| THBS2 | thrombospondin 2 | -0.0217727 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0216898 |
| SQSTM1 | sequestosome 1 | -0.021635 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0215308 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0214608 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0211593 |
