| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.159449 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.139549 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0950408 |
| COL6A3 | collagen, type VI, alpha 3 | 0.09356 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0926931 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0847435 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0672753 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0642259 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0621259 |
| CD44 | CD44 molecule (Indian blood group) | 0.0607924 |
| NDRG1 | N-myc downstream regulated 1 | 0.0604731 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0563774 |
| RTN4 | reticulon 4 | 0.0529553 |
| ZNF292 | zinc finger protein 292 | 0.052933 |
| PCBP2 | poly(rC) binding protein 2 | 0.0516329 |
| RPL11 | ribosomal protein L11 | 0.0508232 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.049597 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0489649 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0473118 |
| FLNA | filamin A, alpha | 0.0461268 |
| LDHA | lactate dehydrogenase A | 0.0461108 |
| ANXA2 | annexin A2 | 0.0459335 |
| RBM25 | RNA binding motif protein 25 | 0.0453708 |
| CANX | calnexin | 0.0446405 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0445495 |
| MATR3 | matrin 3 | 0.04332 |
| RPL3 | ribosomal protein L3 | 0.0432416 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0420313 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0419464 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0419135 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0405355 |
| OGA | O-GlcNAcase | 0.0404293 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0396651 |
| TOP1 | topoisomerase (DNA) I | 0.0384652 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0380434 |
| TPM4 | tropomyosin 4 | 0.0376981 |
| SDC4 | syndecan 4 | 0.0371068 |
| ARRDC3 | arrestin domain containing 3 | 0.0367759 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0365902 |
| GNAS | GNAS complex locus | 0.0364059 |
| MT2A | metallothionein 2A | 0.0363702 |
| RPL13A | ribosomal protein L13a | 0.0362819 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0355527 |
| HBP1 | HMG-box transcription factor 1 | 0.035394 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.034634 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0345407 |
| TPM3 | tropomyosin 3 | 0.0344585 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0333925 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0328816 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0323692 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0323156 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0322203 |
| ERBIN | erbb2 interacting protein | 0.031834 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0316891 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0316538 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0313573 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0309348 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0306706 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0304263 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0303151 |
| HIP1 | huntingtin interacting protein 1 | 0.0302695 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0299866 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0297415 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0292845 |
| THBS1 | thrombospondin 1 | 0.0292164 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0291268 |
| CALR | calreticulin | 0.0290859 |
| RYBP | RING1 and YY1 binding protein | 0.0288818 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0288795 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0286139 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0284826 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0282391 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0281994 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0281587 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0279708 |
| SET | SET nuclear proto-oncogene | 0.0279076 |
| EREG | epiregulin | 0.0278769 |
| SBF2 | SET binding factor 2 | 0.0277606 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0275234 |
| PTMA | prothymosin, alpha | 0.0274265 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0274042 |
| WTAP | Wilms tumor 1 associated protein | 0.0270081 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0267718 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0267657 |
| JMJD1C | jumonji domain containing 1C | 0.0267509 |
| QKI | QKI, KH domain containing, RNA binding | 0.0267104 |
| RACK1 | receptor for activated C kinase 1 | 0.0266208 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0265615 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0264598 |
| FRMD6 | FERM domain containing 6 | 0.0263956 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0263372 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0263346 |
| RPL37A | ribosomal protein L37a | 0.0262294 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0261512 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0260735 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0260679 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0259562 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0258537 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0256573 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0255918 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.329411 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.142399 |
| LOX | lysyl oxidase | -0.107651 |
| TMSB10 | thymosin beta 10 | -0.101495 |
| CDH13 | cadherin 13 | -0.0971972 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0964993 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0924198 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.081161 |
| POTEF | POTE ankyrin domain family, member F | -0.0767623 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0727646 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.060815 |
| STC1 | stanniocalcin 1 | -0.0593434 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0590939 |
| EGFR | epidermal growth factor receptor | -0.0544752 |
| VEGFC | vascular endothelial growth factor C | -0.053527 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0526664 |
| TMEM165 | transmembrane protein 165 | -0.0501739 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0495959 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0484441 |
| COL1A1 | collagen, type I, alpha 1 | -0.0470409 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.046561 |
| CALD1 | caldesmon 1 | -0.044129 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0439551 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0437947 |
| FN1 | fibronectin 1 | -0.0430501 |
| MAP1B | microtubule-associated protein 1B | -0.0429911 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0421926 |
| VCL | vinculin | -0.0410316 |
| GOLGA4 | golgin A4 | -0.0405129 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0403946 |
| GLIS3 | GLIS family zinc finger 3 | -0.0400354 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0394966 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0392335 |
| RASAL2 | RAS protein activator like 2 | -0.0389926 |
| MAP4 | microtubule-associated protein 4 | -0.0386047 |
| PRKCA | protein kinase C, alpha | -0.038487 |
| AHNAK | AHNAK nucleoprotein | -0.0377586 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0370674 |
| B2M | beta-2-microglobulin | -0.0363369 |
| CMIP | c-Maf inducing protein | -0.0359508 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0354397 |
| NBAS | neuroblastoma amplified sequence | -0.0346354 |
| COL1A2 | collagen, type I, alpha 2 | -0.0345009 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.031776 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0314912 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.031442 |
| SEPTIN7 | septin 7 | -0.0307595 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0306938 |
| VIM | vimentin | -0.0306577 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0303629 |
| COL5A1 | collagen, type V, alpha 1 | -0.0303276 |
| KRIT1 | KRIT1, ankyrin repeat containing | -0.0300161 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0299277 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0298822 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0297659 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0294222 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0293897 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0289935 |
| NRXN3 | neurexin 3 | -0.0288005 |
| CALU | calumenin | -0.0281697 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0281116 |
| HLA-C | major histocompatibility complex, class I, C | -0.0278877 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0277858 |
| S100A9 | S100 calcium binding protein A9 | -0.0271818 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0270197 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0269714 |
| MKI67 | marker of proliferation Ki-67 | -0.0268463 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0267176 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0266244 |
| CCDC14 | coiled-coil domain containing 14 | -0.0259816 |
| MGLL | monoglyceride lipase | -0.0259706 |
| FNIP1 | folliculin interacting protein 1 | -0.0258033 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0257763 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0257654 |
| COL5A2 | collagen, type V, alpha 2 | -0.0254443 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0253202 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0251855 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0249772 |
| ATXN1 | ataxin 1 | -0.0249707 |
| HMGA2 | high mobility group AT-hook 2 | -0.0245377 |
| MYOF | myoferlin | -0.0244532 |
| PLCB4 | phospholipase C, beta 4 | -0.0242657 |
| CA12 | carbonic anhydrase XII | -0.0241391 |
| USP8 | ubiquitin specific peptidase 8 | -0.0241316 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0241073 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.024066 |
| SP3 | Sp3 transcription factor | -0.023951 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0238337 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | -0.0238206 |
| LOXL2 | lysyl oxidase-like 2 | -0.0234903 |
| CDK13 | cyclin-dependent kinase 13 | -0.0233739 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0233338 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0231619 |
| CAST | calpastatin | -0.0231216 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0228672 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0228504 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0227193 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0226715 |
| TENM3 | teneurin transmembrane protein 3 | -0.0226278 |
| PFN1 | profilin 1 | -0.0225062 |
