| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dihydroartemisinin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dihydroartemisinin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHA | lactate dehydrogenase A | 0.161391 |
| DSCAM | Down syndrome cell adhesion molecule | 0.131056 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.123197 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.116454 |
| RBM39 | RNA binding motif protein 39 | 0.108429 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0969477 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0826628 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0715311 |
| RPL3 | ribosomal protein L3 | 0.0698474 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0663576 |
| CEP250 | centrosomal protein 250kDa | 0.0653681 |
| CPNE1 | copine I | 0.0646012 |
| CANX | calnexin | 0.0607544 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.058883 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0585342 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0579888 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0576322 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0560289 |
| TPX2 | TPX2, microtubule-associated | 0.0559661 |
| GOLGA4 | golgin A4 | 0.0534755 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0527619 |
| SET | SET nuclear proto-oncogene | 0.0519599 |
| FLNA | filamin A, alpha | 0.0516957 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0515476 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0502617 |
| FMNL2 | formin-like 2 | 0.0493133 |
| MCL1 | myeloid cell leukemia 1 | 0.048515 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0476361 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0462992 |
| HDLBP | high density lipoprotein binding protein | 0.0449515 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0443942 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0442734 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0434087 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0432587 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.04249 |
| NAV2 | neuron navigator 2 | 0.0423441 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.041581 |
| RPL4 | ribosomal protein L4 | 0.0413456 |
| PTMA | prothymosin, alpha | 0.0408486 |
| RPL13A | ribosomal protein L13a | 0.0408367 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0400496 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0397626 |
| FNIP1 | folliculin interacting protein 1 | 0.0387032 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0385006 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0383464 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0382304 |
| PCBP2 | poly(rC) binding protein 2 | 0.0381288 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0380269 |
| SETD5 | SET domain containing 5 | 0.0379987 |
| SPAG9 | sperm associated antigen 9 | 0.037756 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0376203 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0376074 |
| ECT2 | epithelial cell transforming 2 | 0.0374214 |
| MSN | moesin | 0.0372506 |
| SQSTM1 | sequestosome 1 | 0.0371438 |
| RPL18A | ribosomal protein L18a | 0.0369724 |
| CAPRIN2 | caprin family member 2 | 0.0367898 |
| MATR3 | matrin 3 | 0.0366234 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0360191 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0357761 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0353182 |
| TPM4 | tropomyosin 4 | 0.0352768 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0348966 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0344315 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0340057 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.033418 |
| ACTN1 | actinin, alpha 1 | 0.0334045 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0332106 |
| FLNB | filamin B, beta | 0.033125 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.03299 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0329288 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0329216 |
| MTREX | Mtr4 exosome RNA helicase | 0.0328982 |
| RPL23 | ribosomal protein L23 | 0.0326808 |
| SDC4 | syndecan 4 | 0.0326107 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0325392 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0323884 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.032244 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0322306 |
| CENPF | centromere protein F, 350/400kDa | 0.0317254 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0315971 |
| GOLGA3 | golgin A3 | 0.0314351 |
| RBM27 | RNA binding motif protein 27 | 0.0311811 |
| SATB2 | SATB homeobox 2 | 0.0311444 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0309806 |
| OSMR | oncostatin M receptor | 0.0309534 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0307997 |
| SRP54 | signal recognition particle 54kDa | 0.0306395 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0302336 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0300569 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0291133 |
| NPTN | neuroplastin | 0.0291039 |
| TCP1 | t-complex 1 | 0.0289843 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0289656 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0288729 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0287881 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.028655 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0284903 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0282705 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0281799 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.272258 |
| TMSB10 | thymosin beta 10 | -0.0849639 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0719212 |
| POTEF | POTE ankyrin domain family, member F | -0.0561929 |
| MT2A | metallothionein 2A | -0.0471145 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0394225 |
| PFN1 | profilin 1 | -0.0392968 |
| RORA | RAR-related orphan receptor A | -0.0392738 |
| HMGA2 | high mobility group AT-hook 2 | -0.0385897 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0358091 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0351584 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0334831 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0329283 |
| RTN4 | reticulon 4 | -0.0324091 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0320955 |
| TPI1 | triosephosphate isomerase 1 | -0.0316593 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0316332 |
| ANGPTL4 | angiopoietin-like 4 | -0.0310146 |
| ZFHX3 | zinc finger homeobox 3 | -0.0303477 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0302489 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0296871 |
| SVIL | supervillin | -0.029223 |
| HLA-B | major histocompatibility complex, class I, B | -0.0290017 |
| NALCN | sodium leak channel, non selective | -0.0286512 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0275218 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0271669 |
| CDK6 | cyclin-dependent kinase 6 | -0.0271615 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0271611 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0270217 |
| HMGA1 | high mobility group AT-hook 1 | -0.0262894 |
| TMEM123 | transmembrane protein 123 | -0.0257041 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0256741 |
| S100A6 | S100 calcium binding protein A6 | -0.025639 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.025589 |
| RAI14 | retinoic acid induced 14 | -0.0254937 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0254298 |
| EXOC4 | exocyst complex component 4 | -0.0253903 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0253249 |
| PDS5A | PDS5 cohesin associated factor A | -0.0251481 |
| JMJD1C | jumonji domain containing 1C | -0.0249372 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0248349 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0246727 |
| TUBA1B | tubulin, alpha 1b | -0.024658 |
| SNX14 | sorting nexin 14 | -0.0243231 |
| ZNF83 | zinc finger protein 83 | -0.0242093 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0241631 |
| NF1 | neurofibromin 1 | -0.0238942 |
| RPS24 | ribosomal protein S24 | -0.0238175 |
| ACTG1 | actin gamma 1 | -0.0236193 |
| RPS19 | ribosomal protein S19 | -0.0235945 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0235224 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0232707 |
| FMN1 | formin 1 | -0.0232555 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.023102 |
| B2M | beta-2-microglobulin | -0.0230358 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0228771 |
| FTL | ferritin, light polypeptide | -0.0227812 |
| S100A9 | S100 calcium binding protein A9 | -0.0227271 |
| ATG12 | autophagy related 12 | -0.0226322 |
| EFNA5 | ephrin-A5 | -0.022609 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0225914 |
| DEK | DEK proto-oncogene | -0.0225461 |
| CDK19 | cyclin-dependent kinase 19 | -0.0224208 |
| IER3 | immediate early response 3 | -0.0219798 |
| NLK | nemo-like kinase | -0.0216788 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0216033 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0214567 |
| LOC112694756 | uncharaterized LOC112694756 | -0.021407 |
| RPL35A | ribosomal protein L35a | -0.0212066 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0209607 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0208808 |
| PRKCI | protein kinase C, iota | -0.020693 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.020596 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.020491 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0203161 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0203158 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.0202837 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0202202 |
| AK1 | adenylate kinase 1 | -0.020192 |
| GLCCI1 | glucocorticoid induced 1 | -0.0201723 |
| RPL38 | ribosomal protein L38 | -0.0200389 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0199286 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0198858 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0197295 |
| RPS13 | ribosomal protein S13 | -0.0196005 |
| PERP | PERP, TP53 apoptosis effector | -0.0195718 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0194615 |
| DENND4C | DENN/MADD domain containing 4C | -0.0192022 |
| GPC6 | glypican 6 | -0.019108 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0190794 |
| PCNX2 | pecanex 2 | -0.0190181 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0188159 |
| ENO1 | enolase 1, (alpha) | -0.018724 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0187065 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0186334 |
| FMR1 | fragile X mental retardation 1 | -0.0185839 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0185838 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0185136 |
| ZCRB1 | zinc finger CCHC-type and RNA binding motif 1 | -0.0184857 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0184553 |