Diltiazem Gene Set

Dataset	HMDB Metabolites of Enzymes
Category	physical interactions
Type	metabolite
Description	A 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate in which both stereocentres have S configuration. A calcium-channel blocker and vasodilator, it is used as the hydrochloride in the management of angina pectoris and hypertension. (Chemical Entities of Biological Interest Ontology, CHEBI_101278)
External Link	http://www.hmdb.ca/metabolites/HMDB14487
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Genes

9 interacting proteins for the Diltiazem metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol	Name
ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
CACNG1	calcium channel, voltage-dependent, gamma subunit 1
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7