| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.245134 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.101929 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0979604 |
| NAV1 | neuron navigator 1 | 0.0911838 |
| PODXL | podocalyxin-like | 0.0801754 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0769487 |
| CD44 | CD44 molecule (Indian blood group) | 0.0695442 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0612605 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0606408 |
| PLAT | plasminogen activator, tissue | 0.0603084 |
| FBN1 | fibrillin 1 | 0.0594612 |
| COL1A2 | collagen, type I, alpha 2 | 0.058854 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0536494 |
| FLNB | filamin B, beta | 0.0516462 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0501554 |
| RUNX1 | runt-related transcription factor 1 | 0.0487981 |
| SEPTIN9 | septin 9 | 0.043065 |
| C1D | C1D nuclear receptor corepressor | 0.042744 |
| ATP13A3 | ATPase type 13A3 | 0.0418312 |
| AUTS2 | autism susceptibility candidate 2 | 0.0418045 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0403302 |
| APP | amyloid beta (A4) precursor protein | 0.0399849 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.039525 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.038132 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0378141 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0367206 |
| MSN | moesin | 0.0364205 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0344416 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0334964 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0330225 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0327274 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0311036 |
| GPC6 | glypican 6 | 0.0308526 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0305163 |
| L1CAM | L1 cell adhesion molecule | 0.0295091 |
| COL5A2 | collagen, type V, alpha 2 | 0.0294663 |
| GLIS3 | GLIS family zinc finger 3 | 0.0294517 |
| SP3 | Sp3 transcription factor | 0.0294365 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0292011 |
| FLNA | filamin A, alpha | 0.0286305 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0286262 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0285046 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0276685 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0271773 |
| RTN4 | reticulon 4 | 0.0271753 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0267326 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0266327 |
| ZNF292 | zinc finger protein 292 | 0.0261192 |
| ACTN4 | actinin, alpha 4 | 0.0261182 |
| COL5A1 | collagen, type V, alpha 1 | 0.0260537 |
| NOTCH2 | notch 2 | 0.0259884 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0259697 |
| MT2A | metallothionein 2A | 0.0256137 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0246437 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0241169 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0239351 |
| PLD3 | phospholipase D family, member 3 | 0.0238054 |
| MYADM | myeloid-associated differentiation marker | 0.0231003 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0225755 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0222767 |
| SBF2 | SET binding factor 2 | 0.0219815 |
| SETD5 | SET domain containing 5 | 0.0218884 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0218359 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0218261 |
| LAMA5 | laminin, alpha 5 | 0.021728 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0215818 |
| COL6A1 | collagen, type VI, alpha 1 | 0.021459 |
| TPM3 | tropomyosin 3 | 0.0214559 |
| RNF145 | ring finger protein 145 | 0.0213643 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0213027 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0212597 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0210785 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0208856 |
| AFDN | afadin, adherens junction formation factor | 0.0208736 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0207575 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0204855 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0202835 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.020219 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0201558 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0200313 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0192645 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0191366 |
| ADAR | adenosine deaminase, RNA-specific | 0.0190239 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0190183 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0189061 |
| AGRN | agrin | 0.0186089 |
| PRELID2 | PRELI domain containing 2 | 0.0185058 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0184174 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0182478 |
| WTAP | Wilms tumor 1 associated protein | 0.0182427 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0181639 |
| LOX | lysyl oxidase | 0.0178494 |
| VEGFC | vascular endothelial growth factor C | 0.017731 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0176393 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0176183 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0175514 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0173834 |
| MB21D2 | Mab-21 domain containing 2 | 0.0173323 |
| MCL1 | myeloid cell leukemia 1 | 0.0172533 |
| STC1 | stanniocalcin 1 | 0.0172466 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.40935 |
| VIM | vimentin | -0.257688 |
| TMSB10 | thymosin beta 10 | -0.2398 |
| AHNAK | AHNAK nucleoprotein | -0.130725 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.107693 |
| S100A10 | S100 calcium binding protein A10 | -0.0965727 |
| PTMA | prothymosin, alpha | -0.0916214 |
| LMNA | lamin A/C | -0.0760436 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0752814 |
| S100A6 | S100 calcium binding protein A6 | -0.0718509 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0709163 |
| CANX | calnexin | -0.0691443 |
| CSTB | cystatin B (stefin B) | -0.0659652 |
| TPM4 | tropomyosin 4 | -0.0631388 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0629011 |
| CALR | calreticulin | -0.0558043 |
| CCND1 | cyclin D1 | -0.0556058 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0531978 |
| CDH13 | cadherin 13 | -0.0498927 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0493618 |
| FN1 | fibronectin 1 | -0.0489025 |
| TMSB4X | thymosin beta 4, X-linked | -0.0437972 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0437003 |
| FTL | ferritin, light polypeptide | -0.0426578 |
| SQSTM1 | sequestosome 1 | -0.0409624 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0403956 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0394903 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0392933 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0376975 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0376636 |
| RPS24 | ribosomal protein S24 | -0.0359912 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0356496 |
| RRBP1 | ribosome binding protein 1 | -0.0343944 |
| RIGI | RNA sensor RIG-I | -0.0340834 |
| ANXA2 | annexin A2 | -0.0325631 |
| RPL35A | ribosomal protein L35a | -0.0323964 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0313925 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0313797 |
| CAVIN1 | caveolae associated protein 1 | -0.0306773 |
| RPLP1 | ribosomal protein, large, P1 | -0.0303038 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0297931 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0296901 |
| RPL34 | ribosomal protein L34 | -0.0290755 |
| RND3 | Rho family GTPase 3 | -0.0285252 |
| SP100 | SP100 nuclear antigen | -0.0278778 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.027271 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.027189 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0269799 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0267731 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0267052 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0265561 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0265311 |
| HLA-E | major histocompatibility complex, class I, E | -0.0259409 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0256997 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0254488 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0254102 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0249408 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0248852 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0247508 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0244666 |
| GOLGB1 | golgin B1 | -0.0237943 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0237857 |
| LRRC17 | leucine rich repeat containing 17 | -0.0237095 |
| ARF1 | ADP-ribosylation factor 1 | -0.0232843 |
| RPS5 | ribosomal protein S5 | -0.0230322 |
| INSIG1 | insulin induced gene 1 | -0.0229047 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0228005 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0227167 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0226913 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0226508 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0225054 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0222737 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0220397 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0219156 |
| RPS8 | ribosomal protein S8 | -0.0218535 |
| TAOK1 | TAO kinase 1 | -0.0218083 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0213817 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0210704 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0209017 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0208512 |
| RPL19 | ribosomal protein L19 | -0.0208134 |
| RACK1 | receptor for activated C kinase 1 | -0.0206203 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0203615 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0203469 |
| HDLBP | high density lipoprotein binding protein | -0.0199273 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0197506 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0196996 |
| CEP350 | centrosomal protein 350kDa | -0.0196131 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0195101 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.0194858 |
| IL7R | interleukin 7 receptor | -0.0194846 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0193538 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0191465 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0191272 |
| FLT1 | fms-related tyrosine kinase 1 | -0.019037 |
| MAP1B | microtubule-associated protein 1B | -0.0189751 |
| SEC61G | Sec61 gamma subunit | -0.018683 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0186483 |
| S100A11 | S100 calcium binding protein A11 | -0.0186401 |
| S100A4 | S100 calcium binding protein A4 | -0.0186255 |
