| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.106137 |
| TENM3 | teneurin transmembrane protein 3 | 0.0521376 |
| YAP1 | Yes-associated protein 1 | 0.0505162 |
| MMP12 | matrix metallopeptidase 12 | 0.0441479 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0435998 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0430868 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0419137 |
| NLGN1 | neuroligin 1 | 0.0410734 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0395729 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0378924 |
| PDGFC | platelet derived growth factor C | 0.0371448 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.037087 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0361166 |
| DST | dystonin | 0.0352916 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0331292 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0318018 |
| TMEM41B | transmembrane protein 41B | 0.0312826 |
| NEK7 | NIMA-related kinase 7 | 0.0307419 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0292044 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0288794 |
| SMYD3 | SET and MYND domain containing 3 | 0.0284256 |
| ATP11A | ATPase, class VI, type 11A | 0.0283294 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0277462 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0273162 |
| TNPO1 | transportin 1 | 0.0271962 |
| WWOX | WW domain containing oxidoreductase | 0.0271018 |
| KIF5B | kinesin family member 5B | 0.026872 |
| TXNRD1 | thioredoxin reductase 1 | 0.0259904 |
| RRM2 | ribonucleotide reductase M2 | 0.0254021 |
| XPO1 | exportin 1 | 0.024865 |
| GASK1B | golgi associated kinase 1B | 0.0247714 |
| MTAP | methylthioadenosine phosphorylase | 0.0245867 |
| EPHA6 | EPH receptor A6 | 0.0243864 |
| AXIN2 | axin 2 | 0.0242694 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0241554 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0239061 |
| EXOC6B | exocyst complex component 6B | 0.0236163 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0233164 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0231026 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0228395 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0227314 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0224505 |
| MPG | N-methylpurine-DNA glycosylase | 0.0214911 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0213477 |
| H1-0 | H1.0 linker histone | 0.0207687 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0206102 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0205815 |
| MGAT4C | MGAT4 family, member C | 0.0205352 |
| EDARADD | EDAR-associated death domain | 0.0204742 |
| MKI67 | marker of proliferation Ki-67 | 0.0203248 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0202393 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0201299 |
| PGK1 | phosphoglycerate kinase 1 | 0.0199309 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0195548 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0193688 |
| MED13L | mediator complex subunit 13-like | 0.0190933 |
| ZNF217 | zinc finger protein 217 | 0.0190354 |
| USP34 | ubiquitin specific peptidase 34 | 0.0189922 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0188727 |
| RTN4 | reticulon 4 | 0.0188347 |
| IPO7 | importin 7 | 0.0187215 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0187092 |
| VMP1 | vacuole membrane protein 1 | 0.0185784 |
| YBX3 | Y box binding protein 3 | 0.0185409 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0182255 |
| PRRC2A | proline-rich coiled-coil 2A | 0.018115 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0180845 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0180234 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0179654 |
| ENO1 | enolase 1, (alpha) | 0.0175815 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0175801 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0175566 |
| YEATS2 | YEATS domain containing 2 | 0.0175266 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0175172 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0174293 |
| CEP192 | centrosomal protein 192kDa | 0.0173954 |
| LMO7 | LIM domain 7 | 0.0173349 |
| CEP95 | centrosomal protein 95kDa | 0.017065 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0169351 |
| KIAA1328 | KIAA1328 | 0.0167452 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0167043 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0165305 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0164405 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0161947 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0161074 |
| OGA | O-GlcNAcase | 0.015817 |
| CPOX | coproporphyrinogen oxidase | 0.015785 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0156715 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0155889 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0155477 |
| CENPF | centromere protein F, 350/400kDa | 0.0153233 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0152035 |
| NUP153 | nucleoporin 153kDa | 0.0151937 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.015143 |
| LDHA | lactate dehydrogenase A | 0.0149453 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0149136 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0148207 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0147972 |
| VCL | vinculin | 0.0147224 |
| PCDH7 | protocadherin 7 | 0.0146023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0563563 |
| AREG | amphiregulin | -0.0430707 |
| VIM | vimentin | -0.0350805 |
| TMSB10 | thymosin beta 10 | -0.030659 |
| RPL35A | ribosomal protein L35a | -0.0271916 |
| INTS6 | integrator complex subunit 6 | -0.0247984 |
| HMGA2 | high mobility group AT-hook 2 | -0.0244135 |
| FTL | ferritin, light polypeptide | -0.0240207 |
| EHBP1 | EH domain binding protein 1 | -0.023014 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0225377 |
| RPS27A | ribosomal protein S27a | -0.02202 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.02194 |
| RPS8 | ribosomal protein S8 | -0.0204267 |
| RPS23 | ribosomal protein S23 | -0.0202644 |
| EGR1 | early growth response 1 | -0.0193191 |
| RPS3 | ribosomal protein S3 | -0.0188566 |
| RPS29 | ribosomal protein S29 | -0.0186168 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0177916 |
| RPS13 | ribosomal protein S13 | -0.0176467 |
| RPL37A | ribosomal protein L37a | -0.0175878 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0172031 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0168372 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.016837 |
| S100A6 | S100 calcium binding protein A6 | -0.0165589 |
| CALR | calreticulin | -0.016411 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0163631 |
| TUBA1B | tubulin, alpha 1b | -0.0159444 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0159247 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0159112 |
| S100A11 | S100 calcium binding protein A11 | -0.0158347 |
| RPL31 | ribosomal protein L31 | -0.0153876 |
| S100A10 | S100 calcium binding protein A10 | -0.0145323 |
| HMGA1 | high mobility group AT-hook 1 | -0.0142383 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.013742 |
| RPS14 | ribosomal protein S14 | -0.0135101 |
| LRRC23 | leucine rich repeat containing 23 | -0.0134633 |
| TPM4 | tropomyosin 4 | -0.0128879 |
| RPS25 | ribosomal protein S25 | -0.0127903 |
| RPS24 | ribosomal protein S24 | -0.0126992 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0126159 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0125194 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0125114 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0117838 |
| RPL34 | ribosomal protein L34 | -0.0117409 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0116483 |
| RPS27 | ribosomal protein S27 | -0.0115898 |
| CUX1 | cut-like homeobox 1 | -0.011496 |
| TBCA | tubulin folding cofactor A | -0.0114189 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0111216 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0110362 |
| RPL9 | ribosomal protein L9 | -0.0109845 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0109367 |
| RPS6 | ribosomal protein S6 | -0.0108992 |
| RPLP2 | ribosomal protein, large, P2 | -0.0108766 |
| RPS11 | ribosomal protein S11 | -0.0107695 |
| GCG | glucagon | -0.0104999 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0102566 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0101048 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0100659 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0100123 |
| NAV3 | neuron navigator 3 | -0.00983031 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00965783 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0095969 |
| RPS10 | ribosomal protein S10 | -0.00958021 |
| HLA-B | major histocompatibility complex, class I, B | -0.00954218 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00947123 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00946989 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.00929403 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00917945 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.00901263 |
| BRI3BP | BRI3 binding protein | -0.00894804 |
| HLA-A | major histocompatibility complex, class I, A | -0.00885628 |
| RPL36A | ribosomal protein L36a | -0.0088528 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00884158 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.00873981 |
| RPS15 | ribosomal protein S15 | -0.00870999 |
| RPS12 | ribosomal protein S12 | -0.00860672 |
| GNAS | GNAS complex locus | -0.00859472 |
| MYADM | myeloid-associated differentiation marker | -0.00844308 |
| FAM162A | family with sequence similarity 162, member A | -0.00835806 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.00826231 |
| S100A9 | S100 calcium binding protein A9 | -0.0081709 |
| RPL23 | ribosomal protein L23 | -0.00810621 |
| LDHB | lactate dehydrogenase B | -0.00810401 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.00800855 |
| RPL10A | ribosomal protein L10a | -0.00800639 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.00797507 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00795938 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.00795765 |
| SYT1 | synaptotagmin I | -0.00792571 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00789208 |
| CLDN1 | claudin 1 | -0.00777305 |
| EGFR | epidermal growth factor receptor | -0.00771121 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.00768671 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00767191 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00761373 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.00760737 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00757779 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.00755748 |
| RASAL2 | RAS protein activator like 2 | -0.00752663 |
