| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0988784 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0883679 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0881451 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0879102 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0841448 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0679982 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0647973 |
| GPC6 | glypican 6 | 0.0645214 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0637689 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0633268 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0597035 |
| SMAD3 | SMAD family member 3 | 0.0528907 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0504261 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0504234 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0462949 |
| FAT1 | FAT atypical cadherin 1 | 0.045688 |
| NAV2 | neuron navigator 2 | 0.0449336 |
| ATP13A3 | ATPase type 13A3 | 0.044727 |
| COG5 | component of oligomeric golgi complex 5 | 0.0433076 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0426679 |
| FLNA | filamin A, alpha | 0.0423855 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0422053 |
| MSN | moesin | 0.0421595 |
| RUNX1 | runt-related transcription factor 1 | 0.0415782 |
| NRP2 | neuropilin 2 | 0.0410551 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0409801 |
| SBF2 | SET binding factor 2 | 0.0408783 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0402367 |
| SEPTIN9 | septin 9 | 0.0399534 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0398039 |
| WDR43 | WD repeat domain 43 | 0.0395416 |
| RPS2 | ribosomal protein S2 | 0.0389706 |
| TGFB2 | transforming growth factor, beta 2 | 0.0387381 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0386952 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0379213 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0377221 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0374747 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0369531 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0367182 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.036582 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0363524 |
| SUCO | SUN domain containing ossification factor | 0.0351959 |
| ANKRD11 | ankyrin repeat domain 11 | 0.034958 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0347555 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0345628 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0345106 |
| CALU | calumenin | 0.0341389 |
| TNS3 | tensin 3 | 0.0327814 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0325615 |
| CADM1 | cell adhesion molecule 1 | 0.0324871 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0324429 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0315975 |
| PTK2 | protein tyrosine kinase 2 | 0.0314372 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0310313 |
| GLIS3 | GLIS family zinc finger 3 | 0.0308923 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0300167 |
| SP3 | Sp3 transcription factor | 0.0299354 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0297811 |
| TPM3 | tropomyosin 3 | 0.029715 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0296976 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0294168 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.029337 |
| GOLGA4 | golgin A4 | 0.0292577 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0291562 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0286899 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0286666 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0286293 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.028452 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.028327 |
| STOM | stomatin | 0.0281363 |
| RNF216 | ring finger protein 216 | 0.0275388 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0274419 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0272857 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0271888 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0271602 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0269563 |
| SLTM | SAFB-like, transcription modulator | 0.0269561 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0266764 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0265207 |
| CMIP | c-Maf inducing protein | 0.0264038 |
| APP | amyloid beta (A4) precursor protein | 0.0263146 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0260535 |
| CENPF | centromere protein F, 350/400kDa | 0.0260246 |
| NBAS | neuroblastoma amplified sequence | 0.0257007 |
| SPAG9 | sperm associated antigen 9 | 0.0249848 |
| ETV6 | ets variant 6 | 0.0247395 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0247285 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.0245589 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0245421 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0243957 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0242204 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0242185 |
| VMP1 | vacuole membrane protein 1 | 0.0241401 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0239854 |
| PAX8 | paired box 8 | 0.0239775 |
| CRY1 | cryptochrome circadian clock 1 | 0.0239259 |
| CDK13 | cyclin-dependent kinase 13 | 0.0235065 |
| HELZ | helicase with zinc finger | 0.0233525 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0232816 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0231193 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.21809 |
| TMSB10 | thymosin beta 10 | -0.168561 |
| FTL | ferritin, light polypeptide | -0.167537 |
| FRMD4A | FERM domain containing 4A | -0.151294 |
| VIM | vimentin | -0.0939044 |
| CP | ceruloplasmin (ferroxidase) | -0.0913505 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0862413 |
| B2M | beta-2-microglobulin | -0.078057 |
| HLA-B | major histocompatibility complex, class I, B | -0.054248 |
| MT2A | metallothionein 2A | -0.0526746 |
| NDRG1 | N-myc downstream regulated 1 | -0.0503839 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0494874 |
| TXNRD1 | thioredoxin reductase 1 | -0.0459075 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0457796 |
| RPL35A | ribosomal protein L35a | -0.0452852 |
| CALR | calreticulin | -0.0450678 |
| APOL1 | apolipoprotein L, 1 | -0.0441794 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0439251 |
| RIGI | RNA sensor RIG-I | -0.0428341 |
| PTMA | prothymosin, alpha | -0.0412177 |
| RPLP1 | ribosomal protein, large, P1 | -0.0404278 |
| ASPH | aspartate beta-hydroxylase | -0.0396212 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0360385 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0353286 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0343667 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0340106 |
| CA12 | carbonic anhydrase XII | -0.0338492 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0333305 |
| PLIN2 | perilipin 2 | -0.033238 |
| RRBP1 | ribosome binding protein 1 | -0.0324936 |
| S100A11 | S100 calcium binding protein A11 | -0.0321776 |
| RPS24 | ribosomal protein S24 | -0.032057 |
| RPL34 | ribosomal protein L34 | -0.0314051 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0313425 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0309138 |
| RPL31 | ribosomal protein L31 | -0.0306468 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0302789 |
| CTSD | cathepsin D | -0.0296427 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0295782 |
| RPL23 | ribosomal protein L23 | -0.0294339 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0283443 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0281579 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0274846 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0272418 |
| SP100 | SP100 nuclear antigen | -0.0272168 |
| IFI44L | interferon-induced protein 44-like | -0.0269371 |
| RPS19 | ribosomal protein S19 | -0.0264035 |
| HLA-A | major histocompatibility complex, class I, A | -0.0255909 |
| TKT | transketolase | -0.0254632 |
| RPL19 | ribosomal protein L19 | -0.0250809 |
| MMP7 | matrix metallopeptidase 7 | -0.0248737 |
| HLA-E | major histocompatibility complex, class I, E | -0.0247426 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.024692 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0238969 |
| CD63 | CD63 molecule | -0.0237269 |
| LMNA | lamin A/C | -0.0233819 |
| S100A6 | S100 calcium binding protein A6 | -0.0232347 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0232319 |
| HLA-C | major histocompatibility complex, class I, C | -0.0231386 |
| S100A10 | S100 calcium binding protein A10 | -0.0224963 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0224168 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0222455 |
| RPS23 | ribosomal protein S23 | -0.0218675 |
| RNF213 | ring finger protein 213 | -0.0216547 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.021151 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.020951 |
| TRIM56 | tripartite motif containing 56 | -0.0206506 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0206437 |
| CCND1 | cyclin D1 | -0.0196942 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0196368 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0192264 |
| RPL36 | ribosomal protein L36 | -0.0192029 |
| XAF1 | XIAP associated factor 1 | -0.0189749 |
| RPL12 | ribosomal protein L12 | -0.0188925 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0187505 |
| PRKCA | protein kinase C, alpha | -0.0187428 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0185861 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0185514 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0184987 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0183698 |
| RPS21 | ribosomal protein S21 | -0.0182565 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0181264 |
| PKM | pyruvate kinase, muscle | -0.0180885 |
| JUN | jun proto-oncogene | -0.0178211 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.017816 |
| OXR1 | oxidation resistance 1 | -0.0176667 |
| LAP3 | leucine aminopeptidase 3 | -0.0176137 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0175929 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0174986 |
| DIAPH2 | diaphanous-related formin 2 | -0.0174414 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0174128 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0173391 |
| TUBA1B | tubulin, alpha 1b | -0.0173196 |
| EHBP1 | EH domain binding protein 1 | -0.0169202 |
| RPS13 | ribosomal protein S13 | -0.0168615 |
| RPS5 | ribosomal protein S5 | -0.0168475 |
| S100A9 | S100 calcium binding protein A9 | -0.0167596 |
| ANXA4 | annexin A4 | -0.0165893 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0165249 |
| RPL38 | ribosomal protein L38 | -0.0164018 |
