| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.256264 |
| LAMB3 | laminin, beta 3 | 0.178874 |
| FLNB | filamin B, beta | 0.172619 |
| EGFR | epidermal growth factor receptor | 0.169461 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.114617 |
| LMO7 | LIM domain 7 | 0.10782 |
| SLC35F3 | solute carrier family 35, member F3 | 0.105167 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0996851 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0948541 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0913868 |
| MUC17 | mucin 17, cell surface associated | 0.0889157 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.08871 |
| NPSR1 | neuropeptide S receptor 1 | 0.0885441 |
| KLK10 | kallikrein-related peptidase 10 | 0.0840387 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0821256 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0812467 |
| AHNAK | AHNAK nucleoprotein | 0.0802194 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0797423 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0781161 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0781128 |
| VCAN | versican | 0.0767325 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0757449 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0751541 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0717368 |
| TXNIP | thioredoxin interacting protein | 0.0698937 |
| LAMA4 | laminin, alpha 4 | 0.0674128 |
| EZR | ezrin | 0.066582 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0656294 |
| DIAPH2 | diaphanous-related formin 2 | 0.0653472 |
| MCL1 | myeloid cell leukemia 1 | 0.064691 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0633869 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0617057 |
| PRSS3 | protease, serine, 3 | 0.060928 |
| RASAL2 | RAS protein activator like 2 | 0.0595682 |
| TRRAP | transformation/transcription domain-associated protein | 0.0592002 |
| ACTN4 | actinin, alpha 4 | 0.0591058 |
| LOC112694756 | uncharaterized LOC112694756 | 0.057846 |
| PDLIM5 | PDZ and LIM domain 5 | 0.057802 |
| HMGA2 | high mobility group AT-hook 2 | 0.0574434 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0573785 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0568256 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0567973 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0567036 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0562908 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0559547 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0557543 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0554666 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0537703 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0534676 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0525014 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0521716 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0517688 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0515886 |
| SLC38A2 | solute carrier family 38, member 2 | 0.051419 |
| FERMT1 | fermitin family member 1 | 0.0505268 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.050177 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0493117 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.048858 |
| LAMC2 | laminin, gamma 2 | 0.0470757 |
| SDC4 | syndecan 4 | 0.0469985 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0466724 |
| GRB10 | growth factor receptor-bound protein 10 | 0.046554 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0453988 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.0453983 |
| MXD1 | MAX dimerization protein 1 | 0.0448842 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0445189 |
| PGK1 | phosphoglycerate kinase 1 | 0.0442689 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0437631 |
| TXNRD1 | thioredoxin reductase 1 | 0.0435087 |
| CALU | calumenin | 0.0429543 |
| RNF213 | ring finger protein 213 | 0.0424308 |
| PARD3 | par-3 family cell polarity regulator | 0.0415863 |
| KRT8 | keratin 8, type II | 0.0408477 |
| STK39 | serine threonine kinase 39 | 0.040618 |
| PRELID2 | PRELI domain containing 2 | 0.0400232 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0397599 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0391514 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0390786 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0387482 |
| SP100 | SP100 nuclear antigen | 0.0385161 |
| FOXO1 | forkhead box O1 | 0.0379034 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0378988 |
| DIAPH1 | diaphanous-related formin 1 | 0.0376434 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0376334 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0375965 |
| ANXA11 | annexin A11 | 0.037116 |
| SULF2 | sulfatase 2 | 0.0364496 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0356404 |
| OSMR | oncostatin M receptor | 0.0351902 |
| DSPP | dentin sialophosphoprotein | 0.0351821 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.035132 |
| KIAA0040 | KIAA0040 | 0.0346206 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0344679 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.0340935 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.03397 |
| PLEC | plectin | 0.0337283 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0336726 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0334116 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0333299 |
| TPM4 | tropomyosin 4 | 0.0326364 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0944614 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0588797 |
| NDRG1 | N-myc downstream regulated 1 | -0.0517041 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0509826 |
| TMSB10 | thymosin beta 10 | -0.0507709 |
| RPS2 | ribosomal protein S2 | -0.0502255 |
| RPS3 | ribosomal protein S3 | -0.0497835 |
| S100A10 | S100 calcium binding protein A10 | -0.0486707 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0476947 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0442565 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0442527 |
| RPS8 | ribosomal protein S8 | -0.0420317 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0415355 |
| RPLP1 | ribosomal protein, large, P1 | -0.0412872 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0411679 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0397104 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0391012 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0385297 |
| RPL12 | ribosomal protein L12 | -0.0384058 |
| SPAG9 | sperm associated antigen 9 | -0.0379575 |
| RPS12 | ribosomal protein S12 | -0.0374071 |
| RPL7 | ribosomal protein L7 | -0.0372702 |
| MATR3 | matrin 3 | -0.0356782 |
| RPL37A | ribosomal protein L37a | -0.0350985 |
| RPS6 | ribosomal protein S6 | -0.0344577 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0338578 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0335021 |
| EPCAM | epithelial cell adhesion molecule | -0.0331443 |
| RPS27A | ribosomal protein S27a | -0.0329596 |
| RPLP2 | ribosomal protein, large, P2 | -0.0329347 |
| RPS13 | ribosomal protein S13 | -0.0315115 |
| NUP58 | nucleoporin 58 | -0.0307624 |
| RPS23 | ribosomal protein S23 | -0.0300926 |
| RPS29 | ribosomal protein S29 | -0.0293159 |
| FOSL1 | FOS-like antigen 1 | -0.0290728 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0289835 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0289588 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0289383 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0284708 |
| RPS27 | ribosomal protein S27 | -0.0284613 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0281875 |
| RNF145 | ring finger protein 145 | -0.0280477 |
| S100A6 | S100 calcium binding protein A6 | -0.0280319 |
| RPL26 | ribosomal protein L26 | -0.0279071 |
| RPL11 | ribosomal protein L11 | -0.0278325 |
| TOP1 | topoisomerase (DNA) I | -0.0276046 |
| PCBP2 | poly(rC) binding protein 2 | -0.0271839 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0269823 |
| RPL34 | ribosomal protein L34 | -0.0268643 |
| RPL30 | ribosomal protein L30 | -0.0264362 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0263831 |
| RPL5 | ribosomal protein L5 | -0.0256673 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0255915 |
| RPS25 | ribosomal protein S25 | -0.0254404 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0253991 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0248887 |
| ARRDC3 | arrestin domain containing 3 | -0.0247681 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.024623 |
| IPO7 | importin 7 | -0.0245316 |
| NCKAP1 | NCK-associated protein 1 | -0.0245228 |
| QKI | QKI, KH domain containing, RNA binding | -0.0242088 |
| RPS19 | ribosomal protein S19 | -0.0238857 |
| ZNF292 | zinc finger protein 292 | -0.0237089 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0234966 |
| RPL9 | ribosomal protein L9 | -0.0234872 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0234174 |
| RTN4 | reticulon 4 | -0.023304 |
| PNN | pinin, desmosome associated protein | -0.0232922 |
| RPL32 | ribosomal protein L32 | -0.0231366 |
| ZNF706 | zinc finger protein 706 | -0.0231291 |
| RPL8 | ribosomal protein L8 | -0.0230585 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0224519 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0223348 |
| RPL35A | ribosomal protein L35a | -0.0222896 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.022238 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0221648 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0221324 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0221009 |
| RPL31 | ribosomal protein L31 | -0.0218118 |
| RYBP | RING1 and YY1 binding protein | -0.0214527 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0211469 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0207915 |
| RPS24 | ribosomal protein S24 | -0.0207869 |
| RPS21 | ribosomal protein S21 | -0.0206835 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0206286 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0205867 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.020536 |
| HPCAL1 | hippocalcin-like 1 | -0.020259 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0199629 |
| USP3 | ubiquitin specific peptidase 3 | -0.019612 |
| MYO6 | myosin VI | -0.0195646 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0195453 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0193521 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0193186 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0190947 |
| RBM25 | RNA binding motif protein 25 | -0.0190717 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0190588 |
| NOP58 | NOP58 ribonucleoprotein | -0.0190164 |
| SQSTM1 | sequestosome 1 | -0.0190147 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0190117 |
