| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.10589 |
| ACTG1 | actin gamma 1 | 0.0978275 |
| LASP1 | LIM and SH3 protein 1 | 0.0893801 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0850802 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0809519 |
| CLTC | clathrin, heavy chain (Hc) | 0.0759826 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.075332 |
| SMYD3 | SET and MYND domain containing 3 | 0.0731992 |
| ASPH | aspartate beta-hydroxylase | 0.0722533 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0693961 |
| MCL1 | myeloid cell leukemia 1 | 0.0683254 |
| KRT8 | keratin 8, type II | 0.0641663 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0596317 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0593218 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0572613 |
| CEP250 | centrosomal protein 250kDa | 0.0563551 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0560895 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0559021 |
| PTK2 | protein tyrosine kinase 2 | 0.05572 |
| YAP1 | Yes-associated protein 1 | 0.0551895 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.0548671 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0540142 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0530159 |
| DTNA | dystrobrevin, alpha | 0.0519162 |
| SBF2 | SET binding factor 2 | 0.0498221 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.049393 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.048902 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.048698 |
| RPL19 | ribosomal protein L19 | 0.0481042 |
| DSPP | dentin sialophosphoprotein | 0.0478691 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.047554 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0471886 |
| ENO1 | enolase 1, (alpha) | 0.0462665 |
| RAD51B | RAD51 paralog B | 0.0461959 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0447977 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0445456 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0445402 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0444864 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0440557 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0427584 |
| PRELID2 | PRELI domain containing 2 | 0.0406812 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.039742 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0392534 |
| APP | amyloid beta (A4) precursor protein | 0.0385473 |
| LDHA | lactate dehydrogenase A | 0.0382673 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.038205 |
| SP100 | SP100 nuclear antigen | 0.0377938 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0375793 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0373132 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0372558 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0372392 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.036916 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0368 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0365441 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0362381 |
| FAM168A | family with sequence similarity 168, member A | 0.036161 |
| POTEF | POTE ankyrin domain family, member F | 0.0361595 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0360011 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0358024 |
| DST | dystonin | 0.0357286 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0356491 |
| PARD3 | par-3 family cell polarity regulator | 0.0352487 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0352337 |
| TNIK | TRAF2 and NCK interacting kinase | 0.034531 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0340641 |
| MMP24OS | MMP24 opposite strand | 0.0338937 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0338607 |
| NDRG1 | N-myc downstream regulated 1 | 0.0337766 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0334485 |
| SHROOM3 | shroom family member 3 | 0.033145 |
| GOLGB1 | golgin B1 | 0.0329713 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0329068 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0328426 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0326986 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0323689 |
| NF1 | neurofibromin 1 | 0.0312903 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0308198 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0306228 |
| TMSB4X | thymosin beta 4, X-linked | 0.0305419 |
| ATXN1 | ataxin 1 | 0.0303668 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0303038 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0300623 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0297466 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0295144 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0295137 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0291895 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0288304 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0288259 |
| SEPTIN11 | septin 11 | 0.0288255 |
| CDK12 | cyclin-dependent kinase 12 | 0.0286697 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0286587 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0285239 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0283316 |
| ZNF652 | zinc finger protein 652 | 0.0281819 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0279648 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.027888 |
| FAM219A | family with sequence similarity 219, member A | 0.0278007 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0277795 |
| SETD5 | SET domain containing 5 | 0.0276896 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0276074 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.114334 |
| MT2A | metallothionein 2A | -0.104896 |
| S100A8 | S100 calcium binding protein A8 | -0.0646029 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0606293 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0519585 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0482922 |
| S100A9 | S100 calcium binding protein A9 | -0.0457994 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0450432 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0449544 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0413235 |
| S100A14 | S100 calcium binding protein A14 | -0.0382183 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0365067 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0354041 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0321332 |
| NTN4 | netrin 4 | -0.0309555 |
| S100P | S100 calcium binding protein P | -0.0292164 |
| RPLP1 | ribosomal protein, large, P1 | -0.0286097 |
| GRHL1 | grainyhead-like 1 (Drosophila) | -0.0280242 |
| S100A7 | S100 calcium binding protein A7 | -0.0272603 |
| FGB | fibrinogen beta chain | -0.0263835 |
| RPS27 | ribosomal protein S27 | -0.0262266 |
| MIEN1 | migration and invasion enhancer 1 | -0.0259511 |
| RPS29 | ribosomal protein S29 | -0.0256272 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0232472 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0232423 |
| S100A11 | S100 calcium binding protein A11 | -0.0232311 |
| MUCL1 | mucin-like 1 | -0.0231113 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0217555 |
| RPS12 | ribosomal protein S12 | -0.0203675 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0199075 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0197902 |
| USP3 | ubiquitin specific peptidase 3 | -0.0197448 |
| CFB | complement factor B | -0.0194395 |
| IER3 | immediate early response 3 | -0.018887 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0180575 |
| CD44 | CD44 molecule (Indian blood group) | -0.0179693 |
| CD63 | CD63 molecule | -0.01784 |
| YPEL2 | yippee-like 2 (Drosophila) | -0.0176706 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.017615 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0176009 |
| RPL36 | ribosomal protein L36 | -0.0170659 |
| RPS27A | ribosomal protein S27a | -0.0168621 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0167868 |
| SMIM14 | small integral membrane protein 14 | -0.0167708 |
| AREG | amphiregulin | -0.0167157 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -0.0166924 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0166478 |
| HLA-C | major histocompatibility complex, class I, C | -0.0164915 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0164312 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0162304 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0162021 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.01614 |
| LCN2 | lipocalin 2 | -0.0159504 |
| RPS25 | ribosomal protein S25 | -0.0159052 |
| TBCA | tubulin folding cofactor A | -0.0158778 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0158085 |
| RPS3 | ribosomal protein S3 | -0.0157113 |
| RPS6 | ribosomal protein S6 | -0.0156863 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | -0.0154229 |
| SPTSSB | serine palmitoyltransferase, small subunit B | -0.0154166 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0151914 |
| S100A10 | S100 calcium binding protein A10 | -0.0151686 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0150981 |
| RRBP1 | ribosome binding protein 1 | -0.0150178 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0148581 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0147597 |
| RPS24 | ribosomal protein S24 | -0.0145323 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0144975 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0144376 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0143307 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.014223 |
| SEC61G | Sec61 gamma subunit | -0.0142219 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0141518 |
| RPS23 | ribosomal protein S23 | -0.0140874 |
| SERF2 | small EDRK-rich factor 2 | -0.0140588 |
| IFNGR1 | interferon gamma receptor 1 | -0.0140317 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0138758 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0138259 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0138009 |
| TMC5 | transmembrane channel-like 5 | -0.0137662 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | -0.0136088 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0134957 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0134583 |
| HMGB1 | high mobility group box 1 | -0.013418 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0132973 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0131652 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0131302 |
| B2M | beta-2-microglobulin | -0.0130474 |
| CCND1 | cyclin D1 | -0.0130189 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | -0.0130178 |
| RPL28 | ribosomal protein L28 | -0.0129038 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | -0.0128975 |
| FBXO11 | F-box protein 11 | -0.0128794 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0127867 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0127742 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0127727 |
| GNAS | GNAS complex locus | -0.0126117 |
| RPS13 | ribosomal protein S13 | -0.0123436 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0123155 |
| ANKRD30A | ankyrin repeat domain 30A | -0.0121559 |
