| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TENM3 | teneurin transmembrane protein 3 | 0.147932 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.128147 |
| TOX | thymocyte selection-associated high mobility group box | 0.12537 |
| RAD51B | RAD51 paralog B | 0.123294 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.112281 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.110415 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.108688 |
| ZNF608 | zinc finger protein 608 | 0.101542 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0838858 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0814357 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0796658 |
| EFNA5 | ephrin-A5 | 0.0759851 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0709586 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0698349 |
| NEBL | nebulette | 0.0694779 |
| ACTG1 | actin gamma 1 | 0.0662907 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0647154 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0610718 |
| EGR1 | early growth response 1 | 0.0609998 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0585026 |
| SMYD3 | SET and MYND domain containing 3 | 0.0578288 |
| AUTS2 | autism susceptibility candidate 2 | 0.0578184 |
| VCL | vinculin | 0.0556882 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0525998 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.051492 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0506323 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0493964 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.048906 |
| DST | dystonin | 0.0456401 |
| RPL3 | ribosomal protein L3 | 0.04533 |
| RPL11 | ribosomal protein L11 | 0.044473 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0442099 |
| VMP1 | vacuole membrane protein 1 | 0.0434718 |
| MCL1 | myeloid cell leukemia 1 | 0.0429308 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0429141 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0428687 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0425486 |
| FOXO3 | forkhead box O3 | 0.0425286 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0419777 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0416444 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0414882 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0412096 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0411134 |
| CDH18 | cadherin 18, type 2 | 0.0404313 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0400662 |
| RPS4X | ribosomal protein S4, X-linked | 0.0398592 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0398266 |
| TBC1D32 | TBC1 domain family, member 32 | 0.0382629 |
| MLIP | muscular LMNA-interacting protein | 0.0381835 |
| EXOC6B | exocyst complex component 6B | 0.0377788 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0373934 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0368493 |
| VEGFC | vascular endothelial growth factor C | 0.0366718 |
| HHIP | hedgehog interacting protein | 0.0363857 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.035892 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.035619 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0353627 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0348017 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0346064 |
| CABIN1 | calcineurin binding protein 1 | 0.0345694 |
| FMNL2 | formin-like 2 | 0.0342551 |
| ATRN | attractin | 0.0340677 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0339267 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0336425 |
| DIDO1 | death inducer-obliterator 1 | 0.0333966 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0333838 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0320878 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | 0.0314911 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0313715 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.031129 |
| RPL13A | ribosomal protein L13a | 0.0309609 |
| VIM | vimentin | 0.0307581 |
| WLS | wntless Wnt ligand secretion mediator | 0.0306605 |
| TMEM259 | transmembrane protein 259 | 0.0304129 |
| LDHA | lactate dehydrogenase A | 0.0302706 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0302447 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0300845 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0299865 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0297088 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0296248 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0292158 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0291068 |
| MAGEA4 | melanoma antigen family A4 | 0.0289088 |
| SYAP1 | synapse associated protein 1 | 0.0288181 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0285998 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0283627 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0283435 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0283392 |
| SET | SET nuclear proto-oncogene | 0.0282606 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.0279768 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0279075 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0275773 |
| FLNA | filamin A, alpha | 0.0275474 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0272316 |
| DENND1A | DENN/MADD domain containing 1A | 0.0270444 |
| RPLP0 | ribosomal protein, large, P0 | 0.0268919 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0268159 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0264208 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0262134 |
| PTCH1 | patched 1 | 0.02584 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0827078 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0656305 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0637209 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0577869 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0577468 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0568452 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0563931 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0498568 |
| MKI67 | marker of proliferation Ki-67 | -0.0465902 |
| PTMA | prothymosin, alpha | -0.0456268 |
| MATR3 | matrin 3 | -0.0440417 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0439656 |
| XPO1 | exportin 1 | -0.0419065 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0406213 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0399476 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.038692 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0383956 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0379591 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0378626 |
| SETD5 | SET domain containing 5 | -0.0378558 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0370349 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0361704 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0354736 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0351842 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0351137 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.035105 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0344362 |
| FBXO11 | F-box protein 11 | -0.0321813 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0321036 |
| ACACA | acetyl-CoA carboxylase alpha | -0.031807 |
| CADM2 | cell adhesion molecule 2 | -0.0318062 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0316991 |
| FNBP1L | formin binding protein 1-like | -0.0316097 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0313983 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0313167 |
| RPL7 | ribosomal protein L7 | -0.0310625 |
| SPAG9 | sperm associated antigen 9 | -0.0308618 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0302712 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0298224 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0298101 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0293924 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0291823 |
| RAB10 | RAB10, member RAS oncogene family | -0.029026 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0288301 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0287471 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0282119 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0280379 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0279847 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.027965 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0276261 |
| RPS3 | ribosomal protein S3 | -0.0274498 |
| SRPK2 | SRSF protein kinase 2 | -0.0274118 |
| ZNF292 | zinc finger protein 292 | -0.0272307 |
| SEPTIN7 | septin 7 | -0.0270781 |
| GLG1 | golgi glycoprotein 1 | -0.0266822 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0257883 |
| RNF145 | ring finger protein 145 | -0.0257722 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | -0.0255325 |
| INTS10 | integrator complex subunit 10 | -0.0250294 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.024936 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0245241 |
| RPL38 | ribosomal protein L38 | -0.0244685 |
| WASF2 | WAS protein family, member 2 | -0.0244225 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.024394 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0243341 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.02433 |
| CANX | calnexin | -0.02417 |
| NOP58 | NOP58 ribonucleoprotein | -0.0239101 |
| DGKH | diacylglycerol kinase, eta | -0.0238748 |
| RPL31 | ribosomal protein L31 | -0.0237475 |
| NUP58 | nucleoporin 58 | -0.0237268 |
| RPS12 | ribosomal protein S12 | -0.0237146 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0236493 |
| SNX3 | sorting nexin 3 | -0.0236094 |
| RTN3 | reticulon 3 | -0.023586 |
| RNF115 | ring finger protein 115 | -0.0233988 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0233737 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0233021 |
| SSR1 | signal sequence receptor, alpha | -0.0232367 |
| INSIG2 | insulin induced gene 2 | -0.0231371 |
| PAPOLA | poly(A) polymerase alpha | -0.0222827 |
| MAP4 | microtubule-associated protein 4 | -0.0222817 |
| RPLP1 | ribosomal protein, large, P1 | -0.0221765 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0219784 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0219771 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0219764 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0217457 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0216857 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0215794 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0214873 |
| PDS5B | PDS5 cohesin associated factor B | -0.0211065 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0210883 |
| QKI | QKI, KH domain containing, RNA binding | -0.0210435 |
| RPS29 | ribosomal protein S29 | -0.0210203 |
| FAM162A | family with sequence similarity 162, member A | -0.0209955 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0209316 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0209254 |
| CDC27 | cell division cycle 27 | -0.0204775 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0202939 |
| CERT1 | ceramide transporter 1 | -0.020271 |