| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.27092 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0720783 |
| VGF | VGF nerve growth factor inducible | 0.0693393 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0624048 |
| NDRG1 | N-myc downstream regulated 1 | 0.0529211 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0491131 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0481699 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0455835 |
| ENO1 | enolase 1, (alpha) | 0.0430871 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0425764 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0413347 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0411742 |
| IGF1R | insulin-like growth factor 1 receptor | 0.038399 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0381332 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0374411 |
| TNNC1 | troponin C type 1 (slow) | 0.0352981 |
| STOM | stomatin | 0.035181 |
| CD109 | CD109 molecule | 0.0350082 |
| SFTPA2 | surfactant protein A2 | 0.0340099 |
| TMEM178B | transmembrane protein 178B | 0.0338866 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0328688 |
| LDHA | lactate dehydrogenase A | 0.0312547 |
| FBXO7 | F-box protein 7 | 0.029486 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0290878 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0290288 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0283773 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0283428 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0280831 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0278702 |
| HLA-B | major histocompatibility complex, class I, B | 0.0271007 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0269615 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0267345 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.026579 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0262671 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0258025 |
| NAV2 | neuron navigator 2 | 0.0257767 |
| ASPH | aspartate beta-hydroxylase | 0.02546 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0251228 |
| PTMA | prothymosin, alpha | 0.0244096 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0242626 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.023921 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0238371 |
| RAD51B | RAD51 paralog B | 0.0236253 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0231675 |
| ATXN1 | ataxin 1 | 0.0229535 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0229298 |
| RPL3 | ribosomal protein L3 | 0.0226546 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0223988 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0223017 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0220808 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0220725 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0210241 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0208464 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.020297 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0202642 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0202341 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0202246 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0196054 |
| GANAB | glucosidase, alpha; neutral AB | 0.0195864 |
| COPA | coatomer protein complex, subunit alpha | 0.0195509 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0194492 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0194012 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0192424 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0192067 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0191748 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0190678 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0190374 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0190247 |
| CANX | calnexin | 0.0190163 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0189087 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0185708 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0184823 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0183812 |
| RNF150 | ring finger protein 150 | 0.0182424 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0181351 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0180492 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0179962 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0179942 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0179802 |
| FMNL2 | formin-like 2 | 0.0178754 |
| PYGB | phosphorylase, glycogen; brain | 0.0178699 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0178277 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0177943 |
| PHF21A | PHD finger protein 21A | 0.0177553 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.017656 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0175743 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0175119 |
| GPHN | gephyrin | 0.0174252 |
| RNF213 | ring finger protein 213 | 0.0171853 |
| SEPTIN9 | septin 9 | 0.0169746 |
| ERBIN | erbb2 interacting protein | 0.0168961 |
| DST | dystonin | 0.0167995 |
| VMP1 | vacuole membrane protein 1 | 0.0165595 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0162891 |
| CEP250 | centrosomal protein 250kDa | 0.0162673 |
| FLNA | filamin A, alpha | 0.0162625 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0161826 |
| MCL1 | myeloid cell leukemia 1 | 0.0159703 |
| PTK2 | protein tyrosine kinase 2 | 0.0158415 |
| VGLL4 | vestigial-like family member 4 | 0.0157582 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21387 |
| VIM | vimentin | -0.129076 |
| MT2A | metallothionein 2A | -0.124407 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0973606 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0698712 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0658585 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0633678 |
| ACTG1 | actin gamma 1 | -0.0631999 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.059869 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0559137 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0538623 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0514604 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0513814 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0479186 |
| IER3 | immediate early response 3 | -0.0470203 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0428404 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0420401 |
| FRMD4A | FERM domain containing 4A | -0.0410297 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0400078 |
| MT1X | metallothionein 1X | -0.0384757 |
| RPLP1 | ribosomal protein, large, P1 | -0.0382378 |
| RLF | rearranged L-myc fusion | -0.0366933 |
| S100A6 | S100 calcium binding protein A6 | -0.0361511 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0350318 |
| S100A9 | S100 calcium binding protein A9 | -0.0345287 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0342799 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0341707 |
| RHEB | Ras homolog enriched in brain | -0.0325439 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0320781 |
| YBX3 | Y box binding protein 3 | -0.0314734 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311862 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0300323 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0297196 |
| RPS19 | ribosomal protein S19 | -0.0295881 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0294052 |
| SCFD2 | sec1 family domain containing 2 | -0.0285107 |
| NAV3 | neuron navigator 3 | -0.028342 |
| SEPTIN7 | septin 7 | -0.028219 |
| CTTNBP2 | cortactin binding protein 2 | -0.0277347 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0275227 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.027197 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0271441 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0271313 |
| TPD52 | tumor protein D52 | -0.0270658 |
| RPL30 | ribosomal protein L30 | -0.0270299 |
| RPLP0 | ribosomal protein, large, P0 | -0.0267981 |
| RPS3 | ribosomal protein S3 | -0.0267062 |
| EGR1 | early growth response 1 | -0.0261824 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0256226 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0253508 |
| NPR2 | natriuretic peptide receptor 2 | -0.0247822 |
| MTPN | myotrophin | -0.0247445 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0246102 |
| RRBP1 | ribosome binding protein 1 | -0.0245134 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.0244986 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0238723 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0238434 |
| EHBP1 | EH domain binding protein 1 | -0.0234704 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0234269 |
| RPS12 | ribosomal protein S12 | -0.0232583 |
| NOP58 | NOP58 ribonucleoprotein | -0.0228379 |
| FMN1 | formin 1 | -0.0228024 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0226331 |
| RPL26 | ribosomal protein L26 | -0.0225956 |
| RUNX1 | runt-related transcription factor 1 | -0.0224262 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0224004 |
| ANXA2 | annexin A2 | -0.0222449 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0222367 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0221163 |
| RAB7A | RAB7A, member RAS oncogene family | -0.02209 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.0220057 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0219592 |
| GNAS | GNAS complex locus | -0.0216389 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0214835 |
| HMCN1 | hemicentin 1 | -0.021475 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0214241 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0211902 |
| DENND1A | DENN/MADD domain containing 1A | -0.0210922 |
| RPL18 | ribosomal protein L18 | -0.0210522 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0207019 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0203108 |
| RPL8 | ribosomal protein L8 | -0.0202835 |
| RPL12 | ribosomal protein L12 | -0.0201777 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0201314 |
| FAM162A | family with sequence similarity 162, member A | -0.0199285 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0198556 |
| ATF6 | activating transcription factor 6 | -0.0198549 |
| RGS2 | regulator of G-protein signaling 2 | -0.0196052 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0194808 |
| RPL23 | ribosomal protein L23 | -0.0193953 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0192315 |
| TPR | translocated promoter region, nuclear basket protein | -0.0191458 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0191072 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0190135 |
| TAGLN2 | transgelin 2 | -0.0188816 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0187825 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0187154 |
| RPL19 | ribosomal protein L19 | -0.0184123 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0184051 |
| SEM1 | SEM1 26S proteasome subunit | -0.0183771 |
