| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.148033 |
| SMAD3 | SMAD family member 3 | 0.135463 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.108701 |
| FNDC3B | fibronectin type III domain containing 3B | 0.104022 |
| TGM2 | transglutaminase 2 | 0.0837887 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0831523 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0718422 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0696864 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0695483 |
| MCL1 | myeloid cell leukemia 1 | 0.0669059 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0657864 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0653867 |
| APP | amyloid beta (A4) precursor protein | 0.0626264 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.060944 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0509162 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.050288 |
| FLNB | filamin B, beta | 0.0499726 |
| MYO1E | myosin IE | 0.0484497 |
| ASPH | aspartate beta-hydroxylase | 0.048196 |
| DOCK5 | dedicator of cytokinesis 5 | 0.046364 |
| AGRN | agrin | 0.0459204 |
| FLNA | filamin A, alpha | 0.0440959 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0429809 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.041908 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0407797 |
| DTNA | dystrobrevin, alpha | 0.0390346 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0389992 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0384536 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0384184 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0364625 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0362159 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0361861 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0356538 |
| ACTG1 | actin gamma 1 | 0.0348559 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0333638 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0330652 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0314244 |
| HPCAL1 | hippocalcin-like 1 | 0.0311291 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0310823 |
| RAD51B | RAD51 paralog B | 0.030934 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0307213 |
| MT2A | metallothionein 2A | 0.030682 |
| ANO6 | anoctamin 6 | 0.0305619 |
| SLTM | SAFB-like, transcription modulator | 0.0305388 |
| TMEM51 | transmembrane protein 51 | 0.0295631 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0294009 |
| DUSP5 | dual specificity phosphatase 5 | 0.0291883 |
| YEATS2 | YEATS domain containing 2 | 0.0291297 |
| NOTCH2 | notch 2 | 0.0290376 |
| PLEC | plectin | 0.0287489 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0286911 |
| PFKP | phosphofructokinase, platelet | 0.0286185 |
| CDCP1 | CUB domain containing protein 1 | 0.0283419 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0282937 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0282919 |
| BRD2 | bromodomain containing 2 | 0.0277043 |
| LAMA4 | laminin, alpha 4 | 0.0274477 |
| PDZD8 | PDZ domain containing 8 | 0.0273771 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.027265 |
| LASP1 | LIM and SH3 protein 1 | 0.0268615 |
| BCL2L1 | BCL2-like 1 | 0.0267904 |
| ANXA11 | annexin A11 | 0.026731 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0265339 |
| FNIP1 | folliculin interacting protein 1 | 0.0263316 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0261005 |
| SPAG9 | sperm associated antigen 9 | 0.0260525 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0259885 |
| JUP | junction plakoglobin | 0.0259162 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0255953 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0255384 |
| LAMA5 | laminin, alpha 5 | 0.0254398 |
| ACTN1 | actinin, alpha 1 | 0.0251938 |
| SDC4 | syndecan 4 | 0.0251592 |
| DST | dystonin | 0.0250944 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0250882 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0250169 |
| RNF213 | ring finger protein 213 | 0.0249226 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0248803 |
| MYO5B | myosin VB | 0.0247201 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0246703 |
| CMIP | c-Maf inducing protein | 0.024663 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0244735 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0244053 |
| SMYD3 | SET and MYND domain containing 3 | 0.0242597 |
| APOL1 | apolipoprotein L, 1 | 0.0241673 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0241 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0240758 |
| PRELID2 | PRELI domain containing 2 | 0.0240551 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0236132 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0235114 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0233434 |
| MYOF | myoferlin | 0.0225549 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0223803 |
| KIAA1217 | KIAA1217 | 0.0223613 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0221725 |
| ACTN4 | actinin, alpha 4 | 0.0220581 |
| RPL3 | ribosomal protein L3 | 0.0219443 |
| RBM47 | RNA binding motif protein 47 | 0.0218461 |
| FAM3C | family with sequence similarity 3, member C | 0.0217946 |
| EGR1 | early growth response 1 | 0.0216973 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.181198 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.171047 |
| MMP7 | matrix metallopeptidase 7 | -0.143583 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.128067 |
| TMSB10 | thymosin beta 10 | -0.0943248 |
| CP | ceruloplasmin (ferroxidase) | -0.0760153 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0683196 |
| S100A6 | S100 calcium binding protein A6 | -0.0681524 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0669467 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0646807 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0578827 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0559569 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0556435 |
| B2M | beta-2-microglobulin | -0.0537133 |
| FTL | ferritin, light polypeptide | -0.0535209 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0524595 |
| H1-0 | H1.0 linker histone | -0.0506955 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0484805 |
| VIM | vimentin | -0.048475 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0469482 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0463515 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0451424 |
| LMO7 | LIM domain 7 | -0.0450978 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0436095 |
| MT1X | metallothionein 1X | -0.040197 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0386925 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0385665 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0377379 |
| IER3 | immediate early response 3 | -0.0375192 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.037041 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0363958 |
| ITGA6 | integrin, alpha 6 | -0.0363153 |
| TMSB4X | thymosin beta 4, X-linked | -0.0346301 |
| RPS24 | ribosomal protein S24 | -0.0333668 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0329473 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0318612 |
| UBC | ubiquitin C | -0.0317226 |
| USP3 | ubiquitin specific peptidase 3 | -0.0312479 |
| AHNAK | AHNAK nucleoprotein | -0.0311613 |
| GNAS | GNAS complex locus | -0.0310906 |
| RPS8 | ribosomal protein S8 | -0.0309539 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0308949 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0301692 |
| ANXA2 | annexin A2 | -0.0299859 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0295393 |
| RPS6 | ribosomal protein S6 | -0.0293896 |
| CSTB | cystatin B (stefin B) | -0.0291586 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.029084 |
| RPL34 | ribosomal protein L34 | -0.0287818 |
| EREG | epiregulin | -0.028448 |
| S100A11 | S100 calcium binding protein A11 | -0.0283115 |
| RPL35A | ribosomal protein L35a | -0.028302 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0280324 |
| TMEM123 | transmembrane protein 123 | -0.0278692 |
| DSG2 | desmoglein 2 | -0.0272631 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0270613 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0268858 |
| RBM39 | RNA binding motif protein 39 | -0.0264097 |
| RPL23 | ribosomal protein L23 | -0.0263953 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0263091 |
| S100A10 | S100 calcium binding protein A10 | -0.0262477 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0262379 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0259981 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0252828 |
| RPLP1 | ribosomal protein, large, P1 | -0.0252756 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0250202 |
| RIOK3 | RIO kinase 3 | -0.0248976 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0248445 |
| FAM162A | family with sequence similarity 162, member A | -0.0246953 |
| QKI | QKI, KH domain containing, RNA binding | -0.0246789 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0246479 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0243582 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0237131 |
| PARD3 | par-3 family cell polarity regulator | -0.0232424 |
| S100P | S100 calcium binding protein P | -0.0229878 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0228455 |
| EPCAM | epithelial cell adhesion molecule | -0.0228314 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0226908 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0225826 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0223792 |
| CLINT1 | clathrin interactor 1 | -0.0223281 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0222174 |
| TPI1 | triosephosphate isomerase 1 | -0.0216511 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0212407 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.021224 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0209941 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0208797 |
| CANX | calnexin | -0.0206563 |
| TPM4 | tropomyosin 4 | -0.0204704 |
| RPS27A | ribosomal protein S27a | -0.0203999 |
| TOP1 | topoisomerase (DNA) I | -0.0203906 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0202829 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0202459 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0202363 |
| KRT19 | keratin 19, type I | -0.0201621 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0201371 |
| RPL36A | ribosomal protein L36a | -0.0197863 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0197782 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0197285 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0195207 |
