Dimethyl fumarate_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Dimethyl fumarate perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Dimethyl fumarate_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.144521
LMO7 LIM domain 7 0.115292
STAT1 signal transducer and activator of transcription 1, 91kDa 0.102411
MEIS2 Meis homeobox 2 0.0997524
RUNX1 runt-related transcription factor 1 0.0889319
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0883051
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0827389
NCKAP5 NCK-associated protein 5 0.082526
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0817184
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0798672
MACC1 metastasis associated in colon cancer 1 0.0794792
ZBTB20 zinc finger and BTB domain containing 20 0.0788126
BTBD9 BTB (POZ) domain containing 9 0.0761706
EPHB2 EPH receptor B2 0.0748761
PRELID2 PRELI domain containing 2 0.0717111
PHF3 PHD finger protein 3 0.0713322
MYO1E myosin IE 0.068539
VCL vinculin 0.0667824
RAD51B RAD51 paralog B 0.0654966
STK24 serine/threonine kinase 24 0.0650293
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0603372
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0602639
ATXN1 ataxin 1 0.0567071
ARHGAP26 Rho GTPase activating protein 26 0.0562545
NKD1 naked cuticle homolog 1 (Drosophila) 0.055997
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.0548889
BCLAF1 BCL2-associated transcription factor 1 0.0548151
PATJ PATJ crumbs cell polarity complex component 0.0547929
FOXP1 forkhead box P1 0.0546044
TC2N tandem C2 domains, nuclear 0.0525232
RNF43 ring finger protein 43 0.0520104
PLSCR1 phospholipid scramblase 1 0.0515941
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0514327
DSPP dentin sialophosphoprotein 0.0495843
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0490693
SQSTM1 sequestosome 1 0.0489281
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0461819
RNF213 ring finger protein 213 0.0456272
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0454551
ZNRF3 zinc and ring finger 3 0.0452885
EZR ezrin 0.0443928
CCNL1 cyclin L1 0.0440541
FMN1 formin 1 0.0432828
LPP LIM domain containing preferred translocation partner in lipoma 0.0431749
IRF1 interferon regulatory factor 1 0.042612
MBD5 methyl-CpG binding domain protein 5 0.0424867
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0424805
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.0423099
ETV6 ets variant 6 0.0406918
SCAPER S-phase cyclin A-associated protein in the ER 0.0405264
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0404989
NRIP1 nuclear receptor interacting protein 1 0.0402791
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.0402279
ATP10B ATPase, class V, type 10B 0.0400097
TMEM62 transmembrane protein 62 0.0399787
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0399194
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.0389579
ABHD2 abhydrolase domain containing 2 0.0384921
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0381125
BICRAL BICRA like chromatin remodeling complex associated protein 0.0376409
MBNL2 muscleblind-like splicing regulator 2 0.0374894
MECOM MDS1 and EVI1 complex locus 0.037476
YAP1 Yes-associated protein 1 0.0373145
MUC13 mucin 13, cell surface associated 0.0371694
PARP4 poly (ADP-ribose) polymerase family, member 4 0.036931
DSCAM Down syndrome cell adhesion molecule 0.0361922
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0358544
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.0357907
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0347293
SORBS1 sorbin and SH3 domain containing 1 0.0344512
TRIO trio Rho guanine nucleotide exchange factor 0.0340858
KLF3 Kruppel-like factor 3 (basic) 0.033799
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.033675
MX1 MX dynamin-like GTPase 1 0.0336546
EPSTI1 epithelial stromal interaction 1 (breast) 0.0333379
TRERF1 transcriptional regulating factor 1 0.0332376
EHBP1 EH domain binding protein 1 0.0330756
RHOBTB3 Rho-related BTB domain containing 3 0.0328849
TUFT1 tuftelin 1 0.0325247
DIAPH3 diaphanous-related formin 3 0.0323343
ACTN4 actinin, alpha 4 0.0322952
UBAC2 UBA domain containing 2 0.0322269
EXOC4 exocyst complex component 4 0.0322174
NAMPT nicotinamide phosphoribosyltransferase 0.0317798
ITGA6 integrin, alpha 6 0.0313567
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0311467
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.0310689
IFNGR1 interferon gamma receptor 1 0.0309259
PTBP3 polypyrimidine tract binding protein 3 0.0308296
HDAC4 histone deacetylase 4 0.030595
OARD1 O-acyl-ADP-ribose deacylase 1 0.0304737
GOLGB1 golgin B1 0.0304242
CERS6 ceramide synthase 6 0.0303171
FAT1 FAT atypical cadherin 1 0.0298655
MYH9 myosin, heavy chain 9, non-muscle 0.029795
APLP2 amyloid beta (A4) precursor-like protein 2 0.0296283
ARHGAP32 Rho GTPase activating protein 32 0.0295449
C6ORF132 chromosome 6 open reading frame 132 0.0293095
ADAR adenosine deaminase, RNA-specific 0.0292575
MKI67 marker of proliferation Ki-67 0.0292074

decreased expression

Symbol Name Standardized Value
B2M beta-2-microglobulin -0.0851296
LYZ lysozyme -0.0782113
PTMA prothymosin, alpha -0.0745099
TPT1 tumor protein, translationally-controlled 1 -0.0732287
NDRG1 N-myc downstream regulated 1 -0.0705221
FTL ferritin, light polypeptide -0.0617794
PKM pyruvate kinase, muscle -0.0589248
UBC ubiquitin C -0.0587228
TMSB10 thymosin beta 10 -0.0552923
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0538282
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0466334
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0453699
IFI6 interferon, alpha-inducible protein 6 -0.0441962
FNDC3B fibronectin type III domain containing 3B -0.0418605
RAB7A RAB7A, member RAS oncogene family -0.04087
IGFBP3 insulin-like growth factor binding protein 3 -0.0387985
RPL23 ribosomal protein L23 -0.0384354
ERBIN erbb2 interacting protein -0.037602
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0374552
RPL35A ribosomal protein L35a -0.0367443
RNF149 ring finger protein 149 -0.0365357
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0344655
PERP PERP, TP53 apoptosis effector -0.0334623
MT2A metallothionein 2A -0.0319407
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0310205
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -0.0307474
EPCAM epithelial cell adhesion molecule -0.0284759
RPS24 ribosomal protein S24 -0.0276278
TM4SF19 transmembrane 4 L six family member 19 -0.0275239
IFI27 interferon, alpha-inducible protein 27 -0.0267618
ADM adrenomedullin -0.0266369
NPEPPS aminopeptidase puromycin sensitive -0.0250044
NPSR1 neuropeptide S receptor 1 -0.0248968
TSC22D2 TSC22 domain family, member 2 -0.0247652
CSTB cystatin B (stefin B) -0.0245526
RPL34 ribosomal protein L34 -0.0239251
LCN2 lipocalin 2 -0.0232967
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0229351
IFITM3 interferon induced transmembrane protein 3 -0.0226822
RPLP1 ribosomal protein, large, P1 -0.0221565
SLC38A1 solute carrier family 38, member 1 -0.0221546
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0221033
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0218396
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0217002
RPS19 ribosomal protein S19 -0.0216347
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.020657
ARRDC3 arrestin domain containing 3 -0.0206143
S100A6 S100 calcium binding protein A6 -0.0205875
AREG amphiregulin -0.0205469
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0204442
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0204392
RPS27A ribosomal protein S27a -0.0200671
MXD1 MAX dimerization protein 1 -0.0199706
RPL31 ribosomal protein L31 -0.019906
RPL37A ribosomal protein L37a -0.0195167
WSB1 WD repeat and SOCS box containing 1 -0.0192868
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0191966
MUC20 mucin 20, cell surface associated -0.0191331
IER3 immediate early response 3 -0.0190643
TPI1 triosephosphate isomerase 1 -0.018924
ENO2 enolase 2 (gamma, neuronal) -0.0187694
ISG15 ISG15 ubiquitin-like modifier -0.0187334
WDR45B WD repeat domain 45B -0.0183556
MT1X metallothionein 1X -0.018191
RPL9 ribosomal protein L9 -0.0180197
RPS27 ribosomal protein S27 -0.017844
GNAS GNAS complex locus -0.0177898
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.0177817
ATF4 activating transcription factor 4 -0.01778
LGALS3 lectin, galactoside-binding, soluble, 3 -0.0173526
RPLP2 ribosomal protein, large, P2 -0.0171464
SERF2 small EDRK-rich factor 2 -0.0168567
S100A11 S100 calcium binding protein A11 -0.0167018
EIF1 eukaryotic translation initiation factor 1 -0.0166989
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0166516
RPL36A ribosomal protein L36a -0.0165471
ABLIM1 actin binding LIM protein 1 -0.0165425
CST3 cystatin C -0.0165122
RPS29 ribosomal protein S29 -0.0163488
RAB6A RAB6A, member RAS oncogene family -0.0162914
RPS8 ribosomal protein S8 -0.0162715
PLIN2 perilipin 2 -0.0162469
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0162086
GK glycerol kinase -0.0161771
CLOCK clock circadian regulator -0.0161487
S100A9 S100 calcium binding protein A9 -0.0160732
RPL7L1 ribosomal protein L7-like 1 -0.0160289
H2AC6 H2A clustered histone 6 -0.0160008
ADAM17 ADAM metallopeptidase domain 17 -0.0159973
RPS23 ribosomal protein S23 -0.0159622
S100P S100 calcium binding protein P -0.015931
BAIAP2L1 BAI1-associated protein 2-like 1 -0.0159107
H3-3B H3.3 histone B -0.0159038
RPS3 ribosomal protein S3 -0.0158874
KDM3A lysine (K)-specific demethylase 3A -0.0158036
UBAP2 ubiquitin associated protein 2 -0.0157828
HILPDA hypoxia inducible lipid droplet-associated -0.0157754
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0156596
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -0.0156347
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0153161