| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.124355 |
| COL6A3 | collagen, type VI, alpha 3 | 0.121534 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.100487 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.096157 |
| SMAD3 | SMAD family member 3 | 0.0954734 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0867079 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0823455 |
| NDRG1 | N-myc downstream regulated 1 | 0.079644 |
| EGFR | epidermal growth factor receptor | 0.0792069 |
| GLIS3 | GLIS family zinc finger 3 | 0.0690771 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0652961 |
| GOLGB1 | golgin B1 | 0.064392 |
| CANX | calnexin | 0.0643798 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0619366 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.057118 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0539935 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0532197 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0502932 |
| SEC24D | SEC24 family member D | 0.0482745 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0481009 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0474525 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0468005 |
| PRELID2 | PRELI domain containing 2 | 0.0465322 |
| ANKRD17 | ankyrin repeat domain 17 | 0.046021 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0455433 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0454522 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.044788 |
| SBF2 | SET binding factor 2 | 0.0435929 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0433426 |
| RNF216 | ring finger protein 216 | 0.0416602 |
| ANO6 | anoctamin 6 | 0.0411414 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.041138 |
| COG5 | component of oligomeric golgi complex 5 | 0.0406318 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0398482 |
| GOLGA4 | golgin A4 | 0.0396952 |
| ATXN1 | ataxin 1 | 0.0395576 |
| TXNIP | thioredoxin interacting protein | 0.0387522 |
| STC1 | stanniocalcin 1 | 0.0387106 |
| HDLBP | high density lipoprotein binding protein | 0.038679 |
| ZNF841 | zinc finger protein 841 | 0.0386329 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0382777 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0380291 |
| HDAC9 | histone deacetylase 9 | 0.0374843 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0372137 |
| HELZ | helicase with zinc finger | 0.0367993 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0365684 |
| VMP1 | vacuole membrane protein 1 | 0.0364431 |
| FAM13A | family with sequence similarity 13, member A | 0.0363122 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0358176 |
| SQSTM1 | sequestosome 1 | 0.0357053 |
| AHNAK | AHNAK nucleoprotein | 0.0356746 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0355352 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0349041 |
| LRRC49 | leucine rich repeat containing 49 | 0.0343706 |
| TNNC1 | troponin C type 1 (slow) | 0.0339146 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0337147 |
| TNS3 | tensin 3 | 0.0336824 |
| LOX | lysyl oxidase | 0.0336275 |
| SUCO | SUN domain containing ossification factor | 0.0336233 |
| OGA | O-GlcNAcase | 0.0335331 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0333976 |
| CLTC | clathrin, heavy chain (Hc) | 0.0332151 |
| PMM2 | phosphomannomutase 2 | 0.0331004 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0328732 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0321896 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0321838 |
| FNIP1 | folliculin interacting protein 1 | 0.0320359 |
| HSPA8 | heat shock 70kDa protein 8 | 0.031947 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0317557 |
| FLNA | filamin A, alpha | 0.0314637 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0314186 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0314063 |
| MSN | moesin | 0.0311971 |
| RTN4 | reticulon 4 | 0.0309897 |
| MYOF | myoferlin | 0.0307898 |
| CALU | calumenin | 0.0306995 |
| ZNF292 | zinc finger protein 292 | 0.0306421 |
| SCFD2 | sec1 family domain containing 2 | 0.030205 |
| COPA | coatomer protein complex, subunit alpha | 0.0299672 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0285104 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0282512 |
| SRP54 | signal recognition particle 54kDa | 0.0282037 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0281846 |
| LOXL2 | lysyl oxidase-like 2 | 0.0279822 |
| STK17A | serine/threonine kinase 17a | 0.0278649 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.027713 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0277031 |
| METTL15 | methyltransferase like 15 | 0.0275673 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0272681 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0268447 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0265577 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0264486 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0264308 |
| PCBP3 | poly(rC) binding protein 3 | 0.0262797 |
| TLN1 | talin 1 | 0.0262559 |
| ANXA2 | annexin A2 | 0.026232 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0260829 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0259944 |
| SNX13 | sorting nexin 13 | 0.0259483 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0259376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.208624 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.197891 |
| VIM | vimentin | -0.140903 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.135134 |
| FN1 | fibronectin 1 | -0.111883 |
| B2M | beta-2-microglobulin | -0.0999776 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0919424 |
| MT2A | metallothionein 2A | -0.0918444 |
| HLA-B | major histocompatibility complex, class I, B | -0.0841778 |
| PTMA | prothymosin, alpha | -0.081345 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0612505 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0566645 |
| IGF2 | insulin-like growth factor 2 | -0.0557444 |
| NLGN1 | neuroligin 1 | -0.0526218 |
| HLA-A | major histocompatibility complex, class I, A | -0.0524279 |
| RPL35A | ribosomal protein L35a | -0.048632 |
| POTEF | POTE ankyrin domain family, member F | -0.0469106 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0453161 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0451887 |
| CLMP | CXADR-like membrane protein | -0.0420956 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0416803 |
| TPM4 | tropomyosin 4 | -0.0406263 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.040142 |
| PRSS23 | protease, serine, 23 | -0.0365941 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0356053 |
| RPS6 | ribosomal protein S6 | -0.0351123 |
| CALR | calreticulin | -0.0348498 |
| ACTG1 | actin gamma 1 | -0.0333401 |
| S100A9 | S100 calcium binding protein A9 | -0.0304335 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0297457 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0295773 |
| RPLP1 | ribosomal protein, large, P1 | -0.0290073 |
| CCND1 | cyclin D1 | -0.028953 |
| TPI1 | triosephosphate isomerase 1 | -0.0286298 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0279685 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0276504 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0271968 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.027024 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0269247 |
| RPL34 | ribosomal protein L34 | -0.0268156 |
| S100A6 | S100 calcium binding protein A6 | -0.026083 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0259568 |
| CA9 | carbonic anhydrase IX | -0.0259157 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0256326 |
| S100A10 | S100 calcium binding protein A10 | -0.025359 |
| FTL | ferritin, light polypeptide | -0.0251651 |
| SEC61G | Sec61 gamma subunit | -0.0249308 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0248275 |
| ZNF804A | zinc finger protein 804A | -0.024288 |
| RPS19 | ribosomal protein S19 | -0.0240035 |
| RPL9 | ribosomal protein L9 | -0.0238246 |
| RPL31 | ribosomal protein L31 | -0.0235818 |
| TUBA1B | tubulin, alpha 1b | -0.0234274 |
| RPS8 | ribosomal protein S8 | -0.0233664 |
| RPLP2 | ribosomal protein, large, P2 | -0.0233056 |
| CBX3 | chromobox homolog 3 | -0.0232498 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0231886 |
| FBXO11 | F-box protein 11 | -0.0227628 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0226948 |
| CTSD | cathepsin D | -0.0219545 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0217443 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0217319 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0216993 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.021626 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0215941 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0213011 |
| DIAPH3 | diaphanous-related formin 3 | -0.0212895 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0208761 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0208651 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0207844 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0206424 |
| FAM162A | family with sequence similarity 162, member A | -0.020623 |
| LMNA | lamin A/C | -0.0199308 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0198783 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0198728 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0198462 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0197956 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.019792 |
| PFN1 | profilin 1 | -0.0195227 |
| HLA-C | major histocompatibility complex, class I, C | -0.0193996 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0193151 |
| HIP1 | huntingtin interacting protein 1 | -0.0192489 |
| GNAS | GNAS complex locus | -0.0191391 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0190153 |
| RPS23 | ribosomal protein S23 | -0.0189231 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0189029 |
| RPL23 | ribosomal protein L23 | -0.0185446 |
| HMGA1 | high mobility group AT-hook 1 | -0.0181856 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0180996 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0180101 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0178819 |
| H3-3B | H3.3 histone B | -0.0178147 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0175705 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0175516 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0175512 |
| MKI67 | marker of proliferation Ki-67 | -0.0174812 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0172668 |
| C3 | complement component 3 | -0.0171921 |
| CD151 | CD151 molecule (Raph blood group) | -0.0171565 |
| WLS | wntless Wnt ligand secretion mediator | -0.0171168 |
