| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.158059 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.110472 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.100542 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0952185 |
| PRELID2 | PRELI domain containing 2 | 0.0918573 |
| RAD51B | RAD51 paralog B | 0.0893508 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0879408 |
| ZNF292 | zinc finger protein 292 | 0.0677663 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0670438 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0652385 |
| KRT8 | keratin 8, type II | 0.0638961 |
| MCL1 | myeloid cell leukemia 1 | 0.0620556 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0574126 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0564919 |
| MED13L | mediator complex subunit 13-like | 0.0533987 |
| TXNRD1 | thioredoxin reductase 1 | 0.052116 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0514354 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0511238 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.050452 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0476731 |
| ENO1 | enolase 1, (alpha) | 0.0472263 |
| RPL3 | ribosomal protein L3 | 0.0466058 |
| TENM3 | teneurin transmembrane protein 3 | 0.0456966 |
| PTK2 | protein tyrosine kinase 2 | 0.0454529 |
| FHIT | fragile histidine triad | 0.0454069 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0452569 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0452313 |
| AHNAK | AHNAK nucleoprotein | 0.0447333 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0420896 |
| HELZ | helicase with zinc finger | 0.0412289 |
| SHROOM3 | shroom family member 3 | 0.041161 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0410077 |
| SMYD3 | SET and MYND domain containing 3 | 0.040704 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0404624 |
| ZNF638 | zinc finger protein 638 | 0.0393534 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0384837 |
| BBX | bobby sox homolog (Drosophila) | 0.0383286 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0380361 |
| NF1 | neurofibromin 1 | 0.0378384 |
| FLNB | filamin B, beta | 0.0376773 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0374727 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0374539 |
| YEATS2 | YEATS domain containing 2 | 0.0374475 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0357098 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0352725 |
| SETD5 | SET domain containing 5 | 0.0349276 |
| DSPP | dentin sialophosphoprotein | 0.0348643 |
| ASPH | aspartate beta-hydroxylase | 0.0339501 |
| KIAA1217 | KIAA1217 | 0.0338403 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0335456 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0330833 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0330705 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0326348 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0325182 |
| PGK1 | phosphoglycerate kinase 1 | 0.032337 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0319404 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0318402 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0316917 |
| APP | amyloid beta (A4) precursor protein | 0.031664 |
| SFPQ | splicing factor proline/glutamine-rich | 0.031653 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0315261 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0315092 |
| PLEC | plectin | 0.0314977 |
| VMP1 | vacuole membrane protein 1 | 0.0314829 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0314138 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0313519 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0312515 |
| YAP1 | Yes-associated protein 1 | 0.0311071 |
| EZR | ezrin | 0.0310135 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0305626 |
| CDK19 | cyclin-dependent kinase 19 | 0.0304597 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0301667 |
| JMJD1C | jumonji domain containing 1C | 0.0297815 |
| SBF2 | SET binding factor 2 | 0.0295932 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0295669 |
| SMAD3 | SMAD family member 3 | 0.0294654 |
| PCM1 | pericentriolar material 1 | 0.0292147 |
| SDC4 | syndecan 4 | 0.0291224 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.028888 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0288281 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0286094 |
| MYO1D | myosin ID | 0.0283444 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0283306 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0283206 |
| EXOC4 | exocyst complex component 4 | 0.02817 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0281405 |
| RNF213 | ring finger protein 213 | 0.0281177 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0280304 |
| SEPTIN9 | septin 9 | 0.0279969 |
| SLC38A2 | solute carrier family 38, member 2 | 0.02784 |
| MYOF | myoferlin | 0.0277949 |
| MKI67 | marker of proliferation Ki-67 | 0.0273722 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0271622 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0268099 |
| EXOC6B | exocyst complex component 6B | 0.0267839 |
| PCBP2 | poly(rC) binding protein 2 | 0.0267644 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0265726 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0264844 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0264259 |
| FLNA | filamin A, alpha | 0.0263133 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.221112 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.150343 |
| FTL | ferritin, light polypeptide | -0.0890365 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0801204 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0792505 |
| TMSB10 | thymosin beta 10 | -0.0735933 |
| RPL35A | ribosomal protein L35a | -0.0718419 |
| PTMA | prothymosin, alpha | -0.0686154 |
| RPLP1 | ribosomal protein, large, P1 | -0.0638295 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0634302 |
| RPS8 | ribosomal protein S8 | -0.0605246 |
| RPL34 | ribosomal protein L34 | -0.0598015 |
| RPS6 | ribosomal protein S6 | -0.0460634 |
| RPS24 | ribosomal protein S24 | -0.0445161 |
| RACK1 | receptor for activated C kinase 1 | -0.0425698 |
| RPL31 | ribosomal protein L31 | -0.040717 |
| S100A10 | S100 calcium binding protein A10 | -0.0395454 |
| RPS19 | ribosomal protein S19 | -0.0386877 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0380744 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.037916 |
| CANX | calnexin | -0.0361391 |
| RPS27A | ribosomal protein S27a | -0.035423 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0352599 |
| RPS3 | ribosomal protein S3 | -0.0348545 |
| RPS13 | ribosomal protein S13 | -0.0343313 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0332509 |
| RPS5 | ribosomal protein S5 | -0.0328381 |
| RPL19 | ribosomal protein L19 | -0.0328167 |
| RPLP2 | ribosomal protein, large, P2 | -0.0300927 |
| RPS25 | ribosomal protein S25 | -0.029823 |
| RPLP0 | ribosomal protein, large, P0 | -0.0298169 |
| RPL12 | ribosomal protein L12 | -0.0296351 |
| INTS6 | integrator complex subunit 6 | -0.029297 |
| RPS27 | ribosomal protein S27 | -0.0290818 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0287714 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0287579 |
| RPL18 | ribosomal protein L18 | -0.028602 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0279311 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0273387 |
| RPS23 | ribosomal protein S23 | -0.0266011 |
| RPL38 | ribosomal protein L38 | -0.0264638 |
| RPS29 | ribosomal protein S29 | -0.0263005 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0262257 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0260366 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0259 |
| ARF1 | ADP-ribosylation factor 1 | -0.02575 |
| RPL26 | ribosomal protein L26 | -0.025549 |
| LRRC23 | leucine rich repeat containing 23 | -0.0254933 |
| RPS16 | ribosomal protein S16 | -0.0254523 |
| RPL32 | ribosomal protein L32 | -0.025023 |
| RPS10 | ribosomal protein S10 | -0.0246932 |
| RPL7 | ribosomal protein L7 | -0.0244922 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0243626 |
| SRP72 | signal recognition particle 72kDa | -0.0229827 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0228556 |
| MORF4L2 | mortality factor 4 like 2 | -0.0226142 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0225567 |
| CCNI | cyclin I | -0.0225005 |
| MTDH | metadherin | -0.022341 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.022292 |
| RPL8 | ribosomal protein L8 | -0.0222698 |
| ATF4 | activating transcription factor 4 | -0.0219601 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0218405 |
| RPS15 | ribosomal protein S15 | -0.0218256 |
| RPL23 | ribosomal protein L23 | -0.0217233 |
| CCDC47 | coiled-coil domain containing 47 | -0.0213718 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0212093 |
| CALR | calreticulin | -0.0211818 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.021124 |
| RPL36 | ribosomal protein L36 | -0.0206764 |
| RPS14 | ribosomal protein S14 | -0.0205644 |
| RPS11 | ribosomal protein S11 | -0.020412 |
| S100A9 | S100 calcium binding protein A9 | -0.0203584 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0199888 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0197861 |
| RPL27A | ribosomal protein L27a | -0.0196797 |
| ZNF511 | zinc finger protein 511 | -0.0196225 |
| RPS20 | ribosomal protein S20 | -0.0196116 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0195407 |
| EPCAM | epithelial cell adhesion molecule | -0.0195341 |
| RPL30 | ribosomal protein L30 | -0.0192414 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0190195 |
| SEC61G | Sec61 gamma subunit | -0.018966 |
| YBX1 | Y box binding protein 1 | -0.0189305 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0187291 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0185284 |
| RPL5 | ribosomal protein L5 | -0.0182292 |
| TKT | transketolase | -0.0181854 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0178889 |
| RPS12 | ribosomal protein S12 | -0.0176048 |
| GNAS | GNAS complex locus | -0.0175035 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0171238 |
| RRBP1 | ribosome binding protein 1 | -0.0170172 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0169942 |
| RPS17 | ribosomal protein S17 | -0.0169874 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0169022 |
| RIOK3 | RIO kinase 3 | -0.0168869 |
| RPL7A | ribosomal protein L7a | -0.0166147 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0166053 |
| RPL36A | ribosomal protein L36a | -0.0164445 |
