| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APP | amyloid beta (A4) precursor protein | 0.117246 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.112838 |
| ZNF292 | zinc finger protein 292 | 0.0790118 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0747141 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0741685 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0634019 |
| RNF145 | ring finger protein 145 | 0.056586 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0560715 |
| HELZ | helicase with zinc finger | 0.053558 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0531112 |
| MATR3 | matrin 3 | 0.0522069 |
| SBF2 | SET binding factor 2 | 0.0498265 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0493777 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0471078 |
| SNX9 | sorting nexin 9 | 0.0468712 |
| SMAD3 | SMAD family member 3 | 0.045767 |
| RPL3 | ribosomal protein L3 | 0.0453694 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0440865 |
| AFDN | afadin, adherens junction formation factor | 0.0431168 |
| GOLGA4 | golgin A4 | 0.0423017 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0416916 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0411834 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0408544 |
| B2M | beta-2-microglobulin | 0.0407739 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0404278 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0401536 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0378166 |
| ZNF148 | zinc finger protein 148 | 0.037731 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0364848 |
| CCNL1 | cyclin L1 | 0.036162 |
| RLF | rearranged L-myc fusion | 0.0357034 |
| OGA | O-GlcNAcase | 0.0357027 |
| NCKAP1 | NCK-associated protein 1 | 0.0356254 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0353741 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0352245 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0344884 |
| RPL13A | ribosomal protein L13a | 0.0343661 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0335142 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0334626 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0328691 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0326513 |
| ITGB8 | integrin, beta 8 | 0.0325834 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0323886 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0320775 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0306755 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0305531 |
| HSPA8 | heat shock 70kDa protein 8 | 0.030497 |
| FLNA | filamin A, alpha | 0.0304339 |
| SLMAP | sarcolemma associated protein | 0.0302041 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0297829 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0297224 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0294954 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0294504 |
| DNM2 | dynamin 2 | 0.0293586 |
| SFTPA2 | surfactant protein A2 | 0.0293211 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0293125 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.029229 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0291299 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0283144 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.028182 |
| SDC4 | syndecan 4 | 0.0281282 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0279741 |
| CCNT2 | cyclin T2 | 0.0278593 |
| SETD2 | SET domain containing 2 | 0.0275427 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0275338 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0273784 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0273381 |
| YTHDC1 | YTH domain containing 1 | 0.0272085 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0269289 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.026896 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0266261 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0266065 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0265996 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0265613 |
| SETD5 | SET domain containing 5 | 0.0265409 |
| SFXN1 | sideroflexin 1 | 0.0264883 |
| NEK7 | NIMA-related kinase 7 | 0.0262775 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0262127 |
| WDR45B | WD repeat domain 45B | 0.0260393 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0259644 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0259632 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0258189 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0257739 |
| FOSL1 | FOS-like antigen 1 | 0.0257191 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0256797 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0256426 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0256399 |
| ENO1 | enolase 1, (alpha) | 0.0253742 |
| MIS18BP1 | MIS18 binding protein 1 | 0.025305 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0252376 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0251619 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0247878 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0246735 |
| H1-0 | H1.0 linker histone | 0.0246625 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0245431 |
| USP3 | ubiquitin specific peptidase 3 | 0.0245213 |
| NUP54 | nucleoporin 54kDa | 0.0243935 |
| CSNK1D | casein kinase 1, delta | 0.0243834 |
| PGK1 | phosphoglycerate kinase 1 | 0.0243722 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0243148 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.143937 |
| TMSB10 | thymosin beta 10 | -0.133401 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.107613 |
| MT2A | metallothionein 2A | -0.103312 |
| HMGA2 | high mobility group AT-hook 2 | -0.0987015 |
| RAD51B | RAD51 paralog B | -0.0984436 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0911225 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0852717 |
| AHNAK | AHNAK nucleoprotein | -0.0817274 |
| FHIT | fragile histidine triad | -0.0792979 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.074026 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0681545 |
| LAMA4 | laminin, alpha 4 | -0.0652358 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0627621 |
| NDRG1 | N-myc downstream regulated 1 | -0.0622606 |
| EGFR | epidermal growth factor receptor | -0.0616273 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0603917 |
| CD44 | CD44 molecule (Indian blood group) | -0.0589623 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.057784 |
| PRELID2 | PRELI domain containing 2 | -0.0573345 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0567956 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0557339 |
| LAMC2 | laminin, gamma 2 | -0.0547771 |
| DIAPH3 | diaphanous-related formin 3 | -0.0516766 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0515752 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.049933 |
| INTS6 | integrator complex subunit 6 | -0.0487993 |
| WWOX | WW domain containing oxidoreductase | -0.0486839 |
| ITGA6 | integrin, alpha 6 | -0.0466886 |
| RPL35A | ribosomal protein L35a | -0.0464357 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0440361 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0437557 |
| TPM4 | tropomyosin 4 | -0.0437154 |
| ATG7 | autophagy related 7 | -0.0429164 |
| EXOC4 | exocyst complex component 4 | -0.0425825 |
| SPATA13 | spermatogenesis associated 13 | -0.0421559 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0421194 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0415338 |
| EHBP1 | EH domain binding protein 1 | -0.0414895 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0410214 |
| PCED1B | PC-esterase domain containing 1B | -0.0403636 |
| CCND1 | cyclin D1 | -0.0398126 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0386124 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0381983 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0374655 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0374168 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.0360452 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0359712 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0352157 |
| AEBP2 | AE binding protein 2 | -0.0351338 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0350515 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0342673 |
| SMYD3 | SET and MYND domain containing 3 | -0.0341834 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0335763 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0335654 |
| ATXN1 | ataxin 1 | -0.0331284 |
| S100A10 | S100 calcium binding protein A10 | -0.0331222 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0330008 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0328495 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0328477 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0324667 |
| MYOF | myoferlin | -0.0323945 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0322877 |
| DENND1A | DENN/MADD domain containing 1A | -0.032168 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0318804 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0310628 |
| DIAPH2 | diaphanous-related formin 2 | -0.0308654 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0304812 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0304344 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0303206 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0297697 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0296972 |
| PTMA | prothymosin, alpha | -0.0296619 |
| BPTF | bromodomain PHD finger transcription factor | -0.0292382 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0288691 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0288002 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0287287 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0286384 |
| CDK13 | cyclin-dependent kinase 13 | -0.0285236 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0283864 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0282725 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.02816 |
| SVIL | supervillin | -0.0280294 |
| KRT86 | keratin 86, type II | -0.0275376 |
| ABR | active BCR-related | -0.0275199 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0274512 |
| ZFHX3 | zinc finger homeobox 3 | -0.0272409 |
| CCDC138 | coiled-coil domain containing 138 | -0.0272051 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0271644 |
| ANK2 | ankyrin 2, neuronal | -0.0269395 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0266748 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0265845 |
| UBAP2 | ubiquitin associated protein 2 | -0.0265618 |
| HMGB1 | high mobility group box 1 | -0.0265184 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0264646 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0263592 |
| MYO1E | myosin IE | -0.0262336 |
| PCNX4 | pecanex 4 | -0.025686 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0256736 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0256679 |
