| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.17863 |
| COL6A3 | collagen, type VI, alpha 3 | 0.166753 |
| COL1A1 | collagen, type I, alpha 1 | 0.0939928 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0926822 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.080792 |
| SMAD3 | SMAD family member 3 | 0.0665639 |
| MT2A | metallothionein 2A | 0.0598979 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0579995 |
| ATP13A3 | ATPase type 13A3 | 0.0575359 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0548039 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0538086 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0520288 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0509345 |
| VEGFA | vascular endothelial growth factor A | 0.0503364 |
| ECE1 | endothelin converting enzyme 1 | 0.0469791 |
| NAV2 | neuron navigator 2 | 0.0422729 |
| CD44 | CD44 molecule (Indian blood group) | 0.0421792 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0410607 |
| MSN | moesin | 0.0404481 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0369564 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0368286 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0364693 |
| FLNA | filamin A, alpha | 0.0359845 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0344864 |
| MTSS1 | metastasis suppressor 1 | 0.0326159 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0324113 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0315551 |
| NAV1 | neuron navigator 1 | 0.031456 |
| PLEC | plectin | 0.0312181 |
| PRELID2 | PRELI domain containing 2 | 0.0312127 |
| RASA2 | RAS p21 protein activator 2 | 0.0298761 |
| APP | amyloid beta (A4) precursor protein | 0.0296682 |
| PTK2 | protein tyrosine kinase 2 | 0.029663 |
| AXL | AXL receptor tyrosine kinase | 0.0286658 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0276505 |
| HMGA2 | high mobility group AT-hook 2 | 0.0275131 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0274657 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0273306 |
| NOTCH2 | notch 2 | 0.0261848 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0251866 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.024981 |
| CALU | calumenin | 0.0249676 |
| RPS2 | ribosomal protein S2 | 0.0243112 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0241546 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.023774 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0237223 |
| POTEF | POTE ankyrin domain family, member F | 0.0236105 |
| RUNX1 | runt-related transcription factor 1 | 0.0235448 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0233865 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0232052 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0229593 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0229245 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0228475 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0225113 |
| EGR1 | early growth response 1 | 0.0224887 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0223206 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0221421 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0221171 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0219706 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0219673 |
| SBF2 | SET binding factor 2 | 0.0217509 |
| RPL3 | ribosomal protein L3 | 0.0217216 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.021334 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0213043 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0204998 |
| VEGFC | vascular endothelial growth factor C | 0.020403 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0203718 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0203001 |
| MAP1B | microtubule-associated protein 1B | 0.0200642 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0200003 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0199247 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0198957 |
| PDE10A | phosphodiesterase 10A | 0.0198799 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0198418 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0197456 |
| ICAM1 | intercellular adhesion molecule 1 | 0.019645 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0195576 |
| TNS1 | tensin 1 | 0.0193218 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0192875 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0190961 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0190863 |
| YEATS2 | YEATS domain containing 2 | 0.0189573 |
| CLIC4 | chloride intracellular channel 4 | 0.0189357 |
| ITGB5 | integrin, beta 5 | 0.0188592 |
| SDC4 | syndecan 4 | 0.0188097 |
| SEPTIN9 | septin 9 | 0.0183046 |
| FLNB | filamin B, beta | 0.0182735 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0181528 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0180481 |
| FOSL1 | FOS-like antigen 1 | 0.017896 |
| FSTL1 | follistatin-like 1 | 0.0177995 |
| HLA-A | major histocompatibility complex, class I, A | 0.0177935 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0175157 |
| ANGPTL4 | angiopoietin-like 4 | 0.017495 |
| PFN1 | profilin 1 | 0.0174341 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0171363 |
| CABIN1 | calcineurin binding protein 1 | 0.0170778 |
| GLIS3 | GLIS family zinc finger 3 | 0.0169722 |
| RAD51B | RAD51 paralog B | 0.016925 |
| MYO10 | myosin X | 0.0167509 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.404606 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.356166 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.211665 |
| VIM | vimentin | -0.145482 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.136766 |
| TMSB10 | thymosin beta 10 | -0.110651 |
| IER3 | immediate early response 3 | -0.11002 |
| NDRG1 | N-myc downstream regulated 1 | -0.110001 |
| FTL | ferritin, light polypeptide | -0.0821486 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0701308 |
| CADM1 | cell adhesion molecule 1 | -0.069385 |
| CALR | calreticulin | -0.0597643 |
| AHNAK | AHNAK nucleoprotein | -0.0579611 |
| CANX | calnexin | -0.057917 |
| RPL35A | ribosomal protein L35a | -0.052722 |
| PTMA | prothymosin, alpha | -0.051946 |
| CDH13 | cadherin 13 | -0.0502931 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0446071 |
| MTDH | metadherin | -0.0417749 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0415731 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0415568 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0402849 |
| UBC | ubiquitin C | -0.0393698 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0387582 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0385426 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0378185 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.037078 |
| TPM4 | tropomyosin 4 | -0.037038 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0341038 |
| FBN1 | fibrillin 1 | -0.0332578 |
| RPS8 | ribosomal protein S8 | -0.0313885 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0300083 |
| RRBP1 | ribosome binding protein 1 | -0.0297662 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0290249 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0290141 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0289352 |
| COL3A1 | collagen, type III, alpha 1 | -0.0282578 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0280483 |
| COL1A2 | collagen, type I, alpha 2 | -0.0280462 |
| SQSTM1 | sequestosome 1 | -0.0277844 |
| RPLP1 | ribosomal protein, large, P1 | -0.0273748 |
| RPS24 | ribosomal protein S24 | -0.0272895 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0269278 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0263436 |
| S100A10 | S100 calcium binding protein A10 | -0.0258842 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0257005 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0255778 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0249736 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0248115 |
| TRAM1 | translocation associated membrane protein 1 | -0.0239323 |
| RTN3 | reticulon 3 | -0.0238876 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0238308 |
| GOLGB1 | golgin B1 | -0.0237279 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.023265 |
| RPL31 | ribosomal protein L31 | -0.0231454 |
| S100A9 | S100 calcium binding protein A9 | -0.0231337 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0230253 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0229831 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0228158 |
| MYDGF | myeloid-derived growth factor | -0.0225922 |
| MAP4 | microtubule-associated protein 4 | -0.0225666 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0225553 |
| RPL34 | ribosomal protein L34 | -0.0223058 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0222925 |
| MMP3 | matrix metallopeptidase 3 | -0.0222116 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0221943 |
| HM13 | histocompatibility (minor) 13 | -0.0221522 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0221442 |
| HDLBP | high density lipoprotein binding protein | -0.0220679 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0219728 |
| FAM162A | family with sequence similarity 162, member A | -0.0219021 |
| JUN | jun proto-oncogene | -0.0218399 |
| CAVIN1 | caveolae associated protein 1 | -0.0216589 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0215022 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0205147 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0202062 |
| RND3 | Rho family GTPase 3 | -0.0201669 |
| SELENOK | selenoprotein K | -0.0200612 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0198102 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0197682 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.019618 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0195375 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0194787 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0193608 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0193369 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0192033 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0191711 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0191572 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0190512 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0187349 |
| SP100 | SP100 nuclear antigen | -0.0186966 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0186605 |
| LMNA | lamin A/C | -0.0185363 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0183853 |
| RYBP | RING1 and YY1 binding protein | -0.0182458 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0182443 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0180764 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0179486 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0179029 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0178941 |
