| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EZR | ezrin | 0.145 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.127906 |
| TXNRD1 | thioredoxin reductase 1 | 0.123591 |
| KRT8 | keratin 8, type II | 0.121549 |
| ANXA2 | annexin A2 | 0.113856 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.112566 |
| ACTN4 | actinin, alpha 4 | 0.112458 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.102748 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.102472 |
| NDRG1 | N-myc downstream regulated 1 | 0.0992648 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0949131 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0913495 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0836048 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0804863 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0779506 |
| ATXN1 | ataxin 1 | 0.0770488 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0741191 |
| PTK2 | protein tyrosine kinase 2 | 0.0733604 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0707315 |
| FRY | furry homolog (Drosophila) | 0.0661933 |
| KRT18 | keratin 18, type I | 0.0638984 |
| JUP | junction plakoglobin | 0.0628182 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0612628 |
| STK24 | serine/threonine kinase 24 | 0.0610382 |
| LAMB3 | laminin, beta 3 | 0.0588764 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0572529 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0570842 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0542835 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0541292 |
| KRT19 | keratin 19, type I | 0.0533013 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0531095 |
| ABHD2 | abhydrolase domain containing 2 | 0.0526003 |
| ITGB4 | integrin, beta 4 | 0.0521846 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0511675 |
| PRELID2 | PRELI domain containing 2 | 0.051133 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0507707 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.0498571 |
| ANXA11 | annexin A11 | 0.0497858 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0495083 |
| MSN | moesin | 0.0494766 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0490978 |
| ACTG1 | actin gamma 1 | 0.0487727 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0487537 |
| FAT1 | FAT atypical cadherin 1 | 0.0479086 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.047393 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0472796 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0472581 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0460845 |
| KRT20 | keratin 20, type I | 0.0453733 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0453347 |
| ITGA6 | integrin, alpha 6 | 0.0445574 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0445346 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0440127 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0432131 |
| FBXO32 | F-box protein 32 | 0.0430762 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0429461 |
| DSPP | dentin sialophosphoprotein | 0.0425885 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0423058 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0422902 |
| BCL2L1 | BCL2-like 1 | 0.0419055 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0414522 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0411899 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.041109 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0406647 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0405033 |
| RTN4 | reticulon 4 | 0.0400434 |
| DIAPH2 | diaphanous-related formin 2 | 0.039208 |
| NF1 | neurofibromin 1 | 0.0388373 |
| USP54 | ubiquitin specific peptidase 54 | 0.0381803 |
| PGK1 | phosphoglycerate kinase 1 | 0.0379077 |
| AGRN | agrin | 0.0372047 |
| PLEC | plectin | 0.0371848 |
| LDHA | lactate dehydrogenase A | 0.0370913 |
| PCED1B | PC-esterase domain containing 1B | 0.0364729 |
| YPEL2 | yippee-like 2 (Drosophila) | 0.0364407 |
| WASF2 | WAS protein family, member 2 | 0.03621 |
| SDC4 | syndecan 4 | 0.0361947 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0361497 |
| MUC13 | mucin 13, cell surface associated | 0.0360329 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0357071 |
| FOSL1 | FOS-like antigen 1 | 0.0355853 |
| SBF2 | SET binding factor 2 | 0.0354328 |
| NBEAL1 | neurobeachin-like 1 | 0.0352569 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0348048 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0347284 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0335343 |
| LPIN2 | lipin 2 | 0.033354 |
| FOXP1 | forkhead box P1 | 0.0329815 |
| MCL1 | myeloid cell leukemia 1 | 0.0325485 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0325276 |
| DNM2 | dynamin 2 | 0.0325258 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0325003 |
| RNF43 | ring finger protein 43 | 0.0324996 |
| TNS4 | tensin 4 | 0.032234 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0320031 |
| RPS6 | ribosomal protein S6 | 0.0319483 |
| MTMR10 | myotubularin related protein 10 | 0.031871 |
| CCNL1 | cyclin L1 | 0.0318201 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0316347 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0315616 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.191566 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.134913 |
| FTL | ferritin, light polypeptide | -0.0879467 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0828558 |
| UBC | ubiquitin C | -0.0779518 |
| RPS27A | ribosomal protein S27a | -0.0704997 |
| TMSB10 | thymosin beta 10 | -0.0701104 |
| PTMA | prothymosin, alpha | -0.0618864 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0598343 |
| RPLP1 | ribosomal protein, large, P1 | -0.0593284 |
| TJP1 | tight junction protein 1 | -0.0591093 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0589999 |
| INTS6 | integrator complex subunit 6 | -0.0547578 |
| CALR | calreticulin | -0.0511551 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.050017 |
| CANX | calnexin | -0.0492423 |
| RPL23 | ribosomal protein L23 | -0.0468493 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0427803 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0410334 |
| RPS25 | ribosomal protein S25 | -0.039323 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0388553 |
| RPLP2 | ribosomal protein, large, P2 | -0.0385919 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0382209 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0380658 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0379375 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.037504 |
| RPS24 | ribosomal protein S24 | -0.0360096 |
| SPAG9 | sperm associated antigen 9 | -0.0359775 |
| SMAD3 | SMAD family member 3 | -0.0359316 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0348558 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0347626 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0329242 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0325915 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0320971 |
| PCBP2 | poly(rC) binding protein 2 | -0.0320368 |
| NTN4 | netrin 4 | -0.0311611 |
| RTN3 | reticulon 3 | -0.0305421 |
| ZNF207 | zinc finger protein 207 | -0.0303732 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0302747 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0299162 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0292806 |
| RPS19 | ribosomal protein S19 | -0.0281923 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0281401 |
| GOLGA4 | golgin A4 | -0.028095 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0274134 |
| VMP1 | vacuole membrane protein 1 | -0.0272676 |
| RPS5 | ribosomal protein S5 | -0.0269213 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0265535 |
| HYOU1 | hypoxia up-regulated 1 | -0.0262861 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0258262 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0257141 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0257003 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0256825 |
| OGA | O-GlcNAcase | -0.0256318 |
| RPL19 | ribosomal protein L19 | -0.0255515 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0243179 |
| MAGT1 | magnesium transporter 1 | -0.0240559 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0238657 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0238594 |
| RPS17 | ribosomal protein S17 | -0.0238163 |
| RPL5 | ribosomal protein L5 | -0.0237693 |
| RPL35A | ribosomal protein L35a | -0.0236921 |
| RPL31 | ribosomal protein L31 | -0.0235914 |
| SSR1 | signal sequence receptor, alpha | -0.023281 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | -0.0232015 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0230998 |
| TMEM65 | transmembrane protein 65 | -0.023097 |
| HDLBP | high density lipoprotein binding protein | -0.0230769 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0229131 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0226812 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0223809 |
| SEC24D | SEC24 family member D | -0.0220515 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0215843 |
| NUP98 | nucleoporin 98kDa | -0.0214582 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0212948 |
| RPL34 | ribosomal protein L34 | -0.0209908 |
| TRAM1 | translocation associated membrane protein 1 | -0.0205951 |
| XPOT | exportin, tRNA | -0.020474 |
| RPS23 | ribosomal protein S23 | -0.020266 |
| RPS3 | ribosomal protein S3 | -0.0199459 |
| USP53 | ubiquitin specific peptidase 53 | -0.0199451 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | -0.0197344 |
| RNF24 | ring finger protein 24 | -0.0196213 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0195678 |
| RPL9 | ribosomal protein L9 | -0.0195624 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0195521 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0190978 |
| LURAP1L | leucine rich adaptor protein 1-like | -0.019021 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0190108 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0188603 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0187829 |
| SETX | senataxin | -0.0185626 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0185615 |
| RAB3IP | RAB3A interacting protein | -0.0184805 |
| RYBP | RING1 and YY1 binding protein | -0.0184216 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0183059 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.0182327 |
| RPS11 | ribosomal protein S11 | -0.0182279 |
| RACK1 | receptor for activated C kinase 1 | -0.0180396 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0180265 |
