| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.365283 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.272115 |
| C3 | complement component 3 | 0.261077 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.132035 |
| SLC38A2 | solute carrier family 38, member 2 | 0.129344 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.115879 |
| DSPP | dentin sialophosphoprotein | 0.108348 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0855965 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0837902 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0832988 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0825355 |
| EHBP1 | EH domain binding protein 1 | 0.0785541 |
| TF | transferrin | 0.0765834 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.07533 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0736615 |
| ENO1 | enolase 1, (alpha) | 0.0717154 |
| DST | dystonin | 0.0700497 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0631939 |
| FRMD5 | FERM domain containing 5 | 0.0626919 |
| SDC4 | syndecan 4 | 0.0626299 |
| PEG3 | paternally expressed 3 | 0.0622383 |
| VCL | vinculin | 0.06041 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0539901 |
| ATXN1 | ataxin 1 | 0.0536072 |
| GPC6 | glypican 6 | 0.0528632 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0509895 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.049547 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0482127 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0464481 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0452634 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0449469 |
| TNS1 | tensin 1 | 0.0449412 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0443335 |
| ASPH | aspartate beta-hydroxylase | 0.0441372 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0430943 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0426551 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0423379 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0422694 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0416091 |
| RUNX1 | runt-related transcription factor 1 | 0.0414053 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0412957 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0394648 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0393953 |
| KIF1B | kinesin family member 1B | 0.0383914 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0378761 |
| FAT1 | FAT atypical cadherin 1 | 0.0377049 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0375613 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0373323 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0372708 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.034134 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0339551 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0335104 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0333686 |
| CMIP | c-Maf inducing protein | 0.0331419 |
| EGR1 | early growth response 1 | 0.0323054 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0310869 |
| AFDN | afadin, adherens junction formation factor | 0.0309341 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0306178 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0305273 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0305091 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0301325 |
| H1-0 | H1.0 linker histone | 0.0299853 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0298187 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0288156 |
| SVIL | supervillin | 0.0286262 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0283797 |
| AHR | aryl hydrocarbon receptor | 0.0283487 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0280853 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.027901 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0277577 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.0275147 |
| KIZ | kizuna centrosomal protein | 0.0274372 |
| PRKCA | protein kinase C, alpha | 0.0272594 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0269684 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0266138 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.026545 |
| FOXO1 | forkhead box O1 | 0.0262748 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0259341 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0254056 |
| MCL1 | myeloid cell leukemia 1 | 0.0253593 |
| HMGA1 | high mobility group AT-hook 1 | 0.0253543 |
| CCN2 | cellular communication network factor 2 | 0.0253005 |
| STK17A | serine/threonine kinase 17a | 0.0252803 |
| BCL2L1 | BCL2-like 1 | 0.0247654 |
| PEG10 | paternally expressed 10 | 0.0246443 |
| A2M | alpha-2-macroglobulin | 0.0243361 |
| GPC3 | glypican 3 | 0.024176 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0238761 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.023548 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0230762 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0225166 |
| FAM135A | family with sequence similarity 135, member A | 0.0224773 |
| SEPTIN9 | septin 9 | 0.0221966 |
| SMAD3 | SMAD family member 3 | 0.0221472 |
| JAG1 | jagged 1 | 0.0219928 |
| PTCHD4 | patched domain containing 4 | 0.0219752 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0219453 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0218433 |
| ANO6 | anoctamin 6 | 0.0217151 |
| TNS3 | tensin 3 | 0.0216443 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.134392 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.104018 |
| MT2A | metallothionein 2A | -0.0798435 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0683775 |
| FTL | ferritin, light polypeptide | -0.0508029 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0478902 |
| RPS24 | ribosomal protein S24 | -0.04656 |
| RPS19 | ribosomal protein S19 | -0.0424614 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0410439 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0402732 |
| RPLP1 | ribosomal protein, large, P1 | -0.0379562 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0378159 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0374466 |
| RPS8 | ribosomal protein S8 | -0.0374429 |
| APOE | apolipoprotein E | -0.0372653 |
| RPS27A | ribosomal protein S27a | -0.0363846 |
| TMSB10 | thymosin beta 10 | -0.0360981 |
| PTMA | prothymosin, alpha | -0.0355362 |
| WDR45B | WD repeat domain 45B | -0.034841 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0348098 |
| RPL31 | ribosomal protein L31 | -0.0340951 |
| RPL35A | ribosomal protein L35a | -0.0340005 |
| RPL34 | ribosomal protein L34 | -0.0323472 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0311647 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0309306 |
| RRBP1 | ribosome binding protein 1 | -0.0308108 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0300227 |
| APOA2 | apolipoprotein A-II | -0.0299263 |
| RPS6 | ribosomal protein S6 | -0.0273455 |
| RPL32 | ribosomal protein L32 | -0.0268631 |
| RPL12 | ribosomal protein L12 | -0.026664 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0265565 |
| RPLP2 | ribosomal protein, large, P2 | -0.0265013 |
| RPL9 | ribosomal protein L9 | -0.0262615 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0262549 |
| DTNA | dystrobrevin, alpha | -0.0254715 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0249032 |
| RPL23 | ribosomal protein L23 | -0.0244554 |
| RPL5 | ribosomal protein L5 | -0.0236828 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0236289 |
| RPL37A | ribosomal protein L37a | -0.0236041 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0234944 |
| INSIG2 | insulin induced gene 2 | -0.0233017 |
| RPL7 | ribosomal protein L7 | -0.0232454 |
| NDRG1 | N-myc downstream regulated 1 | -0.0231068 |
| SPAG9 | sperm associated antigen 9 | -0.0228952 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.022596 |
| RPL38 | ribosomal protein L38 | -0.022288 |
| GK | glycerol kinase | -0.0220846 |
| RPLP0 | ribosomal protein, large, P0 | -0.0218338 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0217268 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0216286 |
| RPL26 | ribosomal protein L26 | -0.0210965 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0209955 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0209814 |
| RPS23 | ribosomal protein S23 | -0.0205021 |
| MATR3 | matrin 3 | -0.0204941 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0204376 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.020374 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0200224 |
| USP3 | ubiquitin specific peptidase 3 | -0.0198636 |
| JAK1 | Janus kinase 1 | -0.0196939 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0194346 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.019291 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0192277 |
| GDF15 | growth differentiation factor 15 | -0.0189376 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0188611 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.018822 |
| RPS13 | ribosomal protein S13 | -0.0182045 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0181532 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0179481 |
| MED13L | mediator complex subunit 13-like | -0.0179408 |
| NPR2 | natriuretic peptide receptor 2 | -0.0178814 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0175459 |
| RPL30 | ribosomal protein L30 | -0.0172849 |
| IER3 | immediate early response 3 | -0.0172623 |
| RPS12 | ribosomal protein S12 | -0.0171669 |
| OGA | O-GlcNAcase | -0.0169264 |
| CD2AP | CD2-associated protein | -0.0166395 |
| RPS11 | ribosomal protein S11 | -0.0163158 |
| RPL36 | ribosomal protein L36 | -0.0162605 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.016145 |
| RACK1 | receptor for activated C kinase 1 | -0.0160173 |
| IFNGR1 | interferon gamma receptor 1 | -0.0159976 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.015938 |
| RBM39 | RNA binding motif protein 39 | -0.015919 |
| QKI | QKI, KH domain containing, RNA binding | -0.0158904 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0157703 |
| RPL19 | ribosomal protein L19 | -0.0157311 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0156585 |
| CST3 | cystatin C | -0.0156372 |
| FAM162A | family with sequence similarity 162, member A | -0.0153885 |
| RPS25 | ribosomal protein S25 | -0.0153728 |
| RPS10 | ribosomal protein S10 | -0.0153219 |
| RPL6 | ribosomal protein L6 | -0.0152468 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0152301 |
| RPS3 | ribosomal protein S3 | -0.0152275 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0148987 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0148767 |
| ARRDC3 | arrestin domain containing 3 | -0.014803 |
