| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.111056 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0959658 |
| ATP13A3 | ATPase type 13A3 | 0.0760175 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.07225 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0621847 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0599101 |
| ZNF841 | zinc finger protein 841 | 0.0585965 |
| FLNB | filamin B, beta | 0.054447 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0502911 |
| HLA-A | major histocompatibility complex, class I, A | 0.0479811 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0479439 |
| FLNA | filamin A, alpha | 0.0479281 |
| SMAD3 | SMAD family member 3 | 0.0428286 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0416184 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0404353 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0401607 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0379532 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.036624 |
| MSN | moesin | 0.0357252 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0356544 |
| BCL2L1 | BCL2-like 1 | 0.0354178 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0333493 |
| TPM3 | tropomyosin 3 | 0.0319736 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0293595 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0291762 |
| ARF4 | ADP-ribosylation factor 4 | 0.0290823 |
| ACTN1 | actinin, alpha 1 | 0.0285167 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0284355 |
| ERBIN | erbb2 interacting protein | 0.0278172 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0277589 |
| CALU | calumenin | 0.0268672 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0266873 |
| COL5A1 | collagen, type V, alpha 1 | 0.026424 |
| PODXL | podocalyxin-like | 0.0263584 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0251178 |
| CD44 | CD44 molecule (Indian blood group) | 0.0250358 |
| MCL1 | myeloid cell leukemia 1 | 0.0248905 |
| L1CAM | L1 cell adhesion molecule | 0.0248242 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0245682 |
| OSMR | oncostatin M receptor | 0.0241213 |
| NUP153 | nucleoporin 153kDa | 0.0231681 |
| NEK7 | NIMA-related kinase 7 | 0.0224543 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0224524 |
| CCNL1 | cyclin L1 | 0.0222831 |
| NAV2 | neuron navigator 2 | 0.0218283 |
| DIDO1 | death inducer-obliterator 1 | 0.0217809 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0217046 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | 0.0214727 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0214265 |
| SUCO | SUN domain containing ossification factor | 0.0207878 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0204397 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0203532 |
| TMEM41B | transmembrane protein 41B | 0.0201379 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0196439 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0195865 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0195673 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0194817 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0193934 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0193615 |
| STC2 | stanniocalcin 2 | 0.0193301 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0191318 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0190818 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0190115 |
| ANO6 | anoctamin 6 | 0.0187107 |
| IL6ST | interleukin 6 signal transducer | 0.0186247 |
| XPO6 | exportin 6 | 0.0185033 |
| ZNF148 | zinc finger protein 148 | 0.0184957 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0184759 |
| TMF1 | TATA element modulatory factor 1 | 0.0184126 |
| VEGFC | vascular endothelial growth factor C | 0.0183632 |
| DENND5A | DENN/MADD domain containing 5A | 0.0181629 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0181524 |
| RASA2 | RAS p21 protein activator 2 | 0.0180894 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0180864 |
| TBK1 | TANK-binding kinase 1 | 0.0178203 |
| SDC4 | syndecan 4 | 0.0177854 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0176832 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0175657 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0171461 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0170427 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0168718 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0165768 |
| TLN1 | talin 1 | 0.0164684 |
| USP47 | ubiquitin specific peptidase 47 | 0.0163085 |
| SEPTIN9 | septin 9 | 0.0161742 |
| FAM219A | family with sequence similarity 219, member A | 0.0157147 |
| RPL3 | ribosomal protein L3 | 0.0156189 |
| OSBP | oxysterol binding protein | 0.0155626 |
| YEATS2 | YEATS domain containing 2 | 0.0154262 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0153756 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0153198 |
| SCFD2 | sec1 family domain containing 2 | 0.0152434 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0152378 |
| HELZ | helicase with zinc finger | 0.0151328 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.0150784 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0148116 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0147467 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0147361 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0146991 |
| PMM2 | phosphomannomutase 2 | 0.0146786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.17983 |
| FTL | ferritin, light polypeptide | -0.177438 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.153118 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0969507 |
| FN1 | fibronectin 1 | -0.0938312 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0905357 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0872708 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.079679 |
| MT1X | metallothionein 1X | -0.0784065 |
| TMSB10 | thymosin beta 10 | -0.0712245 |
| DEK | DEK proto-oncogene | -0.069242 |
| RPL35A | ribosomal protein L35a | -0.0685522 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0678385 |
| PTMA | prothymosin, alpha | -0.067578 |
| RPS6 | ribosomal protein S6 | -0.0634358 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0617937 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0598065 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0582503 |
| VIM | vimentin | -0.0550727 |
| INTS6 | integrator complex subunit 6 | -0.053675 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0499215 |
| RPLP2 | ribosomal protein, large, P2 | -0.0485714 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0484873 |
| RPS8 | ribosomal protein S8 | -0.0469594 |
| HMGB1 | high mobility group box 1 | -0.0467299 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0450022 |
| RPL12 | ribosomal protein L12 | -0.0435881 |
| HLA-B | major histocompatibility complex, class I, B | -0.0433822 |
| AHNAK | AHNAK nucleoprotein | -0.0419293 |
| S100A10 | S100 calcium binding protein A10 | -0.0410367 |
| RPL23 | ribosomal protein L23 | -0.0407201 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0392909 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0382829 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0374994 |
| GNAS | GNAS complex locus | -0.0373904 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0359268 |
| RPLP1 | ribosomal protein, large, P1 | -0.0348778 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0336606 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0334334 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0332037 |
| TLE4 | transducin-like enhancer of split 4 | -0.0326074 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0315751 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0312707 |
| ADM | adrenomedullin | -0.030517 |
| RPS24 | ribosomal protein S24 | -0.0304387 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0304234 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0298483 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0295986 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0289348 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0282167 |
| RPL34 | ribosomal protein L34 | -0.0280441 |
| RPS3 | ribosomal protein S3 | -0.0275934 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.027259 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0272268 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0269787 |
| B2M | beta-2-microglobulin | -0.026288 |
| CAVIN1 | caveolae associated protein 1 | -0.0258087 |
| TMSB4X | thymosin beta 4, X-linked | -0.0257214 |
| IER3 | immediate early response 3 | -0.0256377 |
| CCND1 | cyclin D1 | -0.0247529 |
| RPS19 | ribosomal protein S19 | -0.0245955 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0245424 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0244502 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0243426 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0241752 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0238363 |
| RPS21 | ribosomal protein S21 | -0.0237819 |
| RPS13 | ribosomal protein S13 | -0.0237684 |
| S100A6 | S100 calcium binding protein A6 | -0.0233279 |
| PLCB4 | phospholipase C, beta 4 | -0.0232764 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0232659 |
| RPL31 | ribosomal protein L31 | -0.0231713 |
| RAI14 | retinoic acid induced 14 | -0.023142 |
| RPL26 | ribosomal protein L26 | -0.0230085 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0229935 |
| RPS23 | ribosomal protein S23 | -0.0229681 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0228822 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0228584 |
| RPL32 | ribosomal protein L32 | -0.0224254 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0223574 |
| RPL35 | ribosomal protein L35 | -0.0222078 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0221637 |
| CDK6 | cyclin-dependent kinase 6 | -0.0221449 |
| ACTG1 | actin gamma 1 | -0.0220174 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0219248 |
| DIAPH3 | diaphanous-related formin 3 | -0.0217364 |
| PLIN2 | perilipin 2 | -0.0215336 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0215303 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.021435 |
| RPL11 | ribosomal protein L11 | -0.0214128 |
| TPM4 | tropomyosin 4 | -0.0213425 |
| JUN | jun proto-oncogene | -0.0212378 |
| RPL37 | ribosomal protein L37 | -0.0212198 |
| RPL36A | ribosomal protein L36a | -0.0211807 |
| KRT7 | keratin 7, type II | -0.0209643 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0209623 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0208034 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0206779 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.020587 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0205227 |
