| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.17711 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.136981 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.136562 |
| GPC6 | glypican 6 | 0.136178 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.125824 |
| RUNX1 | runt-related transcription factor 1 | 0.116693 |
| MMP12 | matrix metallopeptidase 12 | 0.11079 |
| KIAA1549L | KIAA1549-like | 0.100402 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0978348 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0955241 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.095466 |
| NAV1 | neuron navigator 1 | 0.090825 |
| DTNA | dystrobrevin, alpha | 0.0908072 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0895407 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0814133 |
| FLNA | filamin A, alpha | 0.0806978 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0793748 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0786942 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0758734 |
| ASPH | aspartate beta-hydroxylase | 0.0744621 |
| MCL1 | myeloid cell leukemia 1 | 0.0710105 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0684895 |
| HMGA2 | high mobility group AT-hook 2 | 0.0665087 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0663726 |
| CD109 | CD109 molecule | 0.0663569 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.066063 |
| DST | dystonin | 0.0651727 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0627608 |
| SMAD3 | SMAD family member 3 | 0.061705 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0594001 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0589231 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0586829 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0584442 |
| EGR1 | early growth response 1 | 0.0566216 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0565327 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0563475 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0562322 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0560274 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0559763 |
| LSAMP | limbic system-associated membrane protein | 0.0559296 |
| ACTG1 | actin gamma 1 | 0.0557355 |
| CD44 | CD44 molecule (Indian blood group) | 0.0556179 |
| CALD1 | caldesmon 1 | 0.0548655 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.053887 |
| MYO10 | myosin X | 0.0527864 |
| MSN | moesin | 0.0520879 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0516777 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0515606 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0504242 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0503898 |
| LDHA | lactate dehydrogenase A | 0.0492291 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0488079 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0484979 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0483011 |
| TNNC1 | troponin C type 1 (slow) | 0.0480955 |
| ANO6 | anoctamin 6 | 0.0480439 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0478818 |
| PRKCE | protein kinase C, epsilon | 0.0475561 |
| CTSB | cathepsin B | 0.0473385 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0466109 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0464561 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0464036 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0461596 |
| NTM | neurotrimin | 0.0459538 |
| FRMD6 | FERM domain containing 6 | 0.04587 |
| VCL | vinculin | 0.0455995 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0446863 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0443451 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0435393 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0434084 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0426787 |
| CDH13 | cadherin 13 | 0.0426513 |
| ACTN1 | actinin, alpha 1 | 0.042471 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0416482 |
| HDAC9 | histone deacetylase 9 | 0.0403433 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0402507 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0393089 |
| FN1 | fibronectin 1 | 0.0390947 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0390107 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0388805 |
| NABP1 | nucleic acid binding protein 1 | 0.038312 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0381344 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0372731 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0370377 |
| KIAA1217 | KIAA1217 | 0.0365244 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0362421 |
| PRELID2 | PRELI domain containing 2 | 0.0353971 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0353845 |
| RNF213 | ring finger protein 213 | 0.0352565 |
| SBF2 | SET binding factor 2 | 0.0352133 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0351898 |
| ENO1 | enolase 1, (alpha) | 0.0350654 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0349983 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0349897 |
| JMJD1C | jumonji domain containing 1C | 0.0349166 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0348547 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.034575 |
| CUX1 | cut-like homeobox 1 | 0.0338834 |
| RAD51B | RAD51 paralog B | 0.0338507 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.033444 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.123137 |
| PTMA | prothymosin, alpha | -0.0954571 |
| TMSB10 | thymosin beta 10 | -0.0945689 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0924644 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0770146 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0685876 |
| RPLP1 | ribosomal protein, large, P1 | -0.0649172 |
| RPL35A | ribosomal protein L35a | -0.0629527 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0592878 |
| RPS24 | ribosomal protein S24 | -0.0567945 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0545535 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0543595 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0533022 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0517646 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0482414 |
| RPL23 | ribosomal protein L23 | -0.0468967 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0462331 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0429322 |
| RPS23 | ribosomal protein S23 | -0.0416482 |
| MT2A | metallothionein 2A | -0.0410717 |
| RPL34 | ribosomal protein L34 | -0.0410339 |
| RPL31 | ribosomal protein L31 | -0.0410087 |
| RPL12 | ribosomal protein L12 | -0.0399625 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0385731 |
| RPL7 | ribosomal protein L7 | -0.0385158 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0383107 |
| NUP58 | nucleoporin 58 | -0.0382821 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0380955 |
| RPL36A | ribosomal protein L36a | -0.0367451 |
| RYBP | RING1 and YY1 binding protein | -0.0367079 |
| RPS13 | ribosomal protein S13 | -0.0364876 |
| RPS6 | ribosomal protein S6 | -0.0364223 |
| RPLP2 | ribosomal protein, large, P2 | -0.0353403 |
| RPL32 | ribosomal protein L32 | -0.0350563 |
| RPS19 | ribosomal protein S19 | -0.0339174 |
| RPS8 | ribosomal protein S8 | -0.0330506 |
| MATR3 | matrin 3 | -0.0327547 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0326782 |
| RPS25 | ribosomal protein S25 | -0.0324083 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0319665 |
| RPS27A | ribosomal protein S27a | -0.0312061 |
| FAM162A | family with sequence similarity 162, member A | -0.0311405 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0310503 |
| RPL38 | ribosomal protein L38 | -0.029934 |
| NOP58 | NOP58 ribonucleoprotein | -0.0298931 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0289993 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0286243 |
| SEPTIN7 | septin 7 | -0.0284199 |
| SPAG9 | sperm associated antigen 9 | -0.0284048 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0276554 |
| RLF | rearranged L-myc fusion | -0.027205 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0265069 |
| RPL6 | ribosomal protein L6 | -0.0261042 |
| IER3 | immediate early response 3 | -0.0258998 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0257176 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0253889 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0253232 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0251225 |
| YBX3 | Y box binding protein 3 | -0.0249588 |
| ZNF207 | zinc finger protein 207 | -0.0246976 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0242745 |
| PHIP | pleckstrin homology domain interacting protein | -0.024238 |
| RPL8 | ribosomal protein L8 | -0.0239271 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.023879 |
| RPL19 | ribosomal protein L19 | -0.0236269 |
| GOLGA4 | golgin A4 | -0.0235416 |
| RPS16 | ribosomal protein S16 | -0.0232163 |
| RNF145 | ring finger protein 145 | -0.0229883 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0222632 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0222592 |
| RPL5 | ribosomal protein L5 | -0.0219391 |
| NPR2 | natriuretic peptide receptor 2 | -0.0217643 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0217476 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0216315 |
| RIOK3 | RIO kinase 3 | -0.0209251 |
| QKI | QKI, KH domain containing, RNA binding | -0.0209083 |
| RPS3 | ribosomal protein S3 | -0.0207063 |
| RPL9 | ribosomal protein L9 | -0.0202788 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0202386 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0202242 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0199396 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0197595 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0197592 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0194101 |
| NCKAP1 | NCK-associated protein 1 | -0.0193871 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0193193 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0191542 |
| CLINT1 | clathrin interactor 1 | -0.0190271 |
| RBM39 | RNA binding motif protein 39 | -0.0190105 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0189698 |
| RPL36 | ribosomal protein L36 | -0.0188379 |
| USP3 | ubiquitin specific peptidase 3 | -0.0186273 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0186043 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0186032 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0184885 |
| RPS5 | ribosomal protein S5 | -0.0184132 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0182994 |
| TFRC | transferrin receptor | -0.0182562 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0181248 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0180465 |
