| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.130856 |
| FAT1 | FAT atypical cadherin 1 | 0.0862674 |
| PRELID2 | PRELI domain containing 2 | 0.0766651 |
| RPS2 | ribosomal protein S2 | 0.0706226 |
| RPL3 | ribosomal protein L3 | 0.0701187 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0693731 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.063004 |
| RPS12 | ribosomal protein S12 | 0.0580852 |
| RPS6 | ribosomal protein S6 | 0.0528291 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0491524 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0487729 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.048715 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0461212 |
| ASPH | aspartate beta-hydroxylase | 0.0455497 |
| PKP2 | plakophilin 2 | 0.0450284 |
| ATXN1 | ataxin 1 | 0.0434984 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0427317 |
| MUC13 | mucin 13, cell surface associated | 0.0422014 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0421493 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0406882 |
| SQSTM1 | sequestosome 1 | 0.03916 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0385219 |
| RPL13A | ribosomal protein L13a | 0.0381671 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.036424 |
| ANXA2 | annexin A2 | 0.0363826 |
| EGR1 | early growth response 1 | 0.0361381 |
| TXNRD1 | thioredoxin reductase 1 | 0.0351293 |
| EPHA2 | EPH receptor A2 | 0.0349423 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0344563 |
| INTS6 | integrator complex subunit 6 | 0.0336351 |
| POTEF | POTE ankyrin domain family, member F | 0.0332636 |
| PCBP2 | poly(rC) binding protein 2 | 0.0326986 |
| BRD2 | bromodomain containing 2 | 0.0324135 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.032359 |
| SHROOM3 | shroom family member 3 | 0.0319735 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0311805 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0294352 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0294249 |
| CLDN4 | claudin 4 | 0.0286913 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0286692 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.028501 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0284027 |
| RPL21 | ribosomal protein L21 | 0.0283882 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0283207 |
| CDK19 | cyclin-dependent kinase 19 | 0.0283148 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0281217 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0273154 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0271425 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0265863 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0262975 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0262021 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0260633 |
| RAD51B | RAD51 paralog B | 0.0260037 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0250869 |
| VMP1 | vacuole membrane protein 1 | 0.0250375 |
| MCL1 | myeloid cell leukemia 1 | 0.0249551 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0245283 |
| CALU | calumenin | 0.0244369 |
| RPL28 | ribosomal protein L28 | 0.0239188 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0239165 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0237431 |
| NDRG1 | N-myc downstream regulated 1 | 0.0235209 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0234543 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0233994 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0233449 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0233411 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0233109 |
| RPL27 | ribosomal protein L27 | 0.022879 |
| KIF16B | kinesin family member 16B | 0.0224044 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0223721 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0220372 |
| ANO6 | anoctamin 6 | 0.0215613 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.021134 |
| PGM3 | phosphoglucomutase 3 | 0.0210067 |
| SMYD3 | SET and MYND domain containing 3 | 0.0209217 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0206707 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.020655 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0206427 |
| RPS8 | ribosomal protein S8 | 0.0205289 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0203089 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0202627 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0202381 |
| ARF4 | ADP-ribosylation factor 4 | 0.0202285 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0200372 |
| EFNB2 | ephrin-B2 | 0.0199475 |
| RPSA | ribosomal protein SA | 0.0198196 |
| IRF1 | interferon regulatory factor 1 | 0.0195801 |
| FHL2 | four and a half LIM domains 2 | 0.0195493 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0194818 |
| DUSP5 | dual specificity phosphatase 5 | 0.0193999 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.019286 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0191859 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0190162 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0189262 |
| WWOX | WW domain containing oxidoreductase | 0.0187068 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0184297 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0183815 |
| TRIM2 | tripartite motif containing 2 | 0.0183539 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0182973 |
| EREG | epiregulin | 0.0175892 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.115062 |
| TMSB10 | thymosin beta 10 | -0.102782 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0948697 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0919084 |
| PTMA | prothymosin, alpha | -0.0867758 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0816179 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0747182 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0745419 |
| KRT18 | keratin 18, type I | -0.0690445 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0682118 |
| RPLP1 | ribosomal protein, large, P1 | -0.0626236 |
| DSG2 | desmoglein 2 | -0.0551694 |
| RPS24 | ribosomal protein S24 | -0.0515768 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0502384 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0496384 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0492625 |
| AHNAK | AHNAK nucleoprotein | -0.0470395 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0453365 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0446976 |
| CANX | calnexin | -0.044641 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0436676 |
| LMO7 | LIM domain 7 | -0.0433557 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0432295 |
| AOPEP | aminopeptidase O (putative) | -0.0430198 |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | -0.0415807 |
| RRBP1 | ribosome binding protein 1 | -0.0409333 |
| RBM25 | RNA binding motif protein 25 | -0.0396373 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0395819 |
| FERMT1 | fermitin family member 1 | -0.0392954 |
| PALLD | palladin, cytoskeletal associated protein | -0.0391972 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0382805 |
| NPSR1 | neuropeptide S receptor 1 | -0.0382774 |
| COBL | cordon-bleu WH2 repeat protein | -0.0378616 |
| RPL35A | ribosomal protein L35a | -0.0372454 |
| TSPAN8 | tetraspanin 8 | -0.0370563 |
| MSI2 | musashi RNA-binding protein 2 | -0.0363813 |
| S100A6 | S100 calcium binding protein A6 | -0.0355467 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0352983 |
| SERINC5 | serine incorporator 5 | -0.0352553 |
| EPCAM | epithelial cell adhesion molecule | -0.0348058 |
| RPL31 | ribosomal protein L31 | -0.0344091 |
| CCND1 | cyclin D1 | -0.0342415 |
| SP100 | SP100 nuclear antigen | -0.0341161 |
| RPL34 | ribosomal protein L34 | -0.0333595 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0328206 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0328184 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0323538 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0322811 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0317696 |
| NRN1 | neuritin 1 | -0.0315327 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0312009 |
| XAF1 | XIAP associated factor 1 | -0.0311053 |
| RPL4 | ribosomal protein L4 | -0.0309891 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0308867 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0307108 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.030676 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0301977 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0300253 |
| TPI1 | triosephosphate isomerase 1 | -0.0293103 |
| UBE3C | ubiquitin protein ligase E3C | -0.0287737 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0286755 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0286718 |
| RIGI | RNA sensor RIG-I | -0.0283489 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0283161 |
| MATR3 | matrin 3 | -0.027863 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0277723 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0277098 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.026872 |
| RPL32 | ribosomal protein L32 | -0.0268206 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.0266345 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0266066 |
| FBXO11 | F-box protein 11 | -0.0266047 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0263423 |
| IER3 | immediate early response 3 | -0.0261992 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0261792 |
| RPS27A | ribosomal protein S27a | -0.0260815 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0259314 |
| CDK6 | cyclin-dependent kinase 6 | -0.0258191 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0257806 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0255393 |
| PERP | PERP, TP53 apoptosis effector | -0.0254598 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0253017 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0251299 |
| SULF2 | sulfatase 2 | -0.0244122 |
| PLAC8 | placenta-specific 8 | -0.0241711 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.024146 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0240163 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0239114 |
| TPM4 | tropomyosin 4 | -0.0237028 |
| GNAS | GNAS complex locus | -0.0237003 |
| SH3D19 | SH3 domain containing 19 | -0.0236627 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.023608 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0234014 |
| MCU | mitochondrial calcium uniporter | -0.0233612 |
| CCNI | cyclin I | -0.0232216 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0229298 |
| RPS23 | ribosomal protein S23 | -0.0228589 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.022642 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.022456 |
| RNF217 | ring finger protein 217 | -0.0223988 |
