| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CES1 | carboxylesterase 1 | 0.133711 |
| EGFR | epidermal growth factor receptor | 0.0859856 |
| MCL1 | myeloid cell leukemia 1 | 0.0817185 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0673191 |
| FAM13A | family with sequence similarity 13, member A | 0.0672438 |
| NDRG1 | N-myc downstream regulated 1 | 0.0657048 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0630238 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0600722 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0559988 |
| SLTM | SAFB-like, transcription modulator | 0.0557508 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0519059 |
| LAMC2 | laminin, gamma 2 | 0.0511097 |
| NGLY1 | N-glycanase 1 | 0.0484883 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.046327 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.045192 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0448038 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0425914 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0387723 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0358566 |
| FRY | furry homolog (Drosophila) | 0.0334352 |
| RUNX1 | runt-related transcription factor 1 | 0.0326632 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0324073 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0306895 |
| YEATS2 | YEATS domain containing 2 | 0.030378 |
| MYO1B | myosin IB | 0.0303141 |
| CDCP1 | CUB domain containing protein 1 | 0.0293859 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0282923 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0281128 |
| LAMA4 | laminin, alpha 4 | 0.0281032 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0280214 |
| ANO6 | anoctamin 6 | 0.0278239 |
| OSMR | oncostatin M receptor | 0.0272377 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0263265 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0262584 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0255507 |
| LAMB3 | laminin, beta 3 | 0.0251328 |
| ZNF292 | zinc finger protein 292 | 0.0248873 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0248214 |
| SMAD3 | SMAD family member 3 | 0.0245025 |
| PLEC | plectin | 0.024284 |
| CCNL1 | cyclin L1 | 0.0242702 |
| TMEM45B | transmembrane protein 45B | 0.0242129 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0238258 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0234037 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0225629 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.022526 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0222338 |
| SDC4 | syndecan 4 | 0.0221469 |
| RASA2 | RAS p21 protein activator 2 | 0.0214257 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0214208 |
| GPATCH2L | G patch domain containing 2-like | 0.0213635 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0211962 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0211409 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0208235 |
| TMEM165 | transmembrane protein 165 | 0.0206433 |
| RLIM | ring finger protein, LIM domain interacting | 0.0205553 |
| RAB27B | RAB27B, member RAS oncogene family | 0.020546 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0204468 |
| PYGL | phosphorylase, glycogen, liver | 0.0201955 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0200342 |
| ZNF638 | zinc finger protein 638 | 0.0199207 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0198774 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.01973 |
| TXNRD1 | thioredoxin reductase 1 | 0.0195237 |
| STC1 | stanniocalcin 1 | 0.0195107 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0194608 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0194328 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0194301 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0192996 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0192635 |
| TPM3 | tropomyosin 3 | 0.0191718 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0189093 |
| WDR26 | WD repeat domain 26 | 0.0187867 |
| SNX9 | sorting nexin 9 | 0.0187818 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0185961 |
| DOCK5 | dedicator of cytokinesis 5 | 0.018396 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0183953 |
| CCNG2 | cyclin G2 | 0.0183212 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0183006 |
| RPL3 | ribosomal protein L3 | 0.0182706 |
| MSN | moesin | 0.0182265 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0180115 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0180085 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0178469 |
| RNF149 | ring finger protein 149 | 0.0178455 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0178336 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0177261 |
| DTNA | dystrobrevin, alpha | 0.0177131 |
| C1D | C1D nuclear receptor corepressor | 0.017655 |
| FAT1 | FAT atypical cadherin 1 | 0.0172182 |
| OGA | O-GlcNAcase | 0.017175 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0171711 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0171517 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0169037 |
| DUSP5 | dual specificity phosphatase 5 | 0.0168419 |
| ATP13A3 | ATPase type 13A3 | 0.0168195 |
| FNIP1 | folliculin interacting protein 1 | 0.0168169 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0168069 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0166831 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.0166131 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.210757 |
| TMSB10 | thymosin beta 10 | -0.13323 |
| MT2A | metallothionein 2A | -0.103715 |
| ASPH | aspartate beta-hydroxylase | -0.0831874 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0816637 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0813677 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0802293 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0761538 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0711138 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0704986 |
| RPS3 | ribosomal protein S3 | -0.0666103 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0647449 |
| PTMA | prothymosin, alpha | -0.0641284 |
| MYOF | myoferlin | -0.0616293 |
| FTL | ferritin, light polypeptide | -0.0597709 |
| SEC61G | Sec61 gamma subunit | -0.058156 |
| RPLP1 | ribosomal protein, large, P1 | -0.0576934 |
| S100A10 | S100 calcium binding protein A10 | -0.0566653 |
| INTS6 | integrator complex subunit 6 | -0.0563672 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0562397 |
| RPL35A | ribosomal protein L35a | -0.05083 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0505172 |
| ACTG1 | actin gamma 1 | -0.0489025 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0452809 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0442615 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0438313 |
| RPS24 | ribosomal protein S24 | -0.0433495 |
| RPS8 | ribosomal protein S8 | -0.0431516 |
| RPS12 | ribosomal protein S12 | -0.0424437 |
| RPS25 | ribosomal protein S25 | -0.040586 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0396568 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0393214 |
| RPL37A | ribosomal protein L37a | -0.0382505 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.038177 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.038077 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0368975 |
| KRT7 | keratin 7, type II | -0.0366654 |
| ANXA2 | annexin A2 | -0.0365638 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0359907 |
| RPS27A | ribosomal protein S27a | -0.035245 |
| RPS6 | ribosomal protein S6 | -0.0343886 |
| RPL34 | ribosomal protein L34 | -0.0334877 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0334268 |
| RPS23 | ribosomal protein S23 | -0.0334179 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0332668 |
| HOMER1 | homer scaffolding protein 1 | -0.0321884 |
| KRT18 | keratin 18, type I | -0.0320741 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.031518 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0308855 |
| S100P | S100 calcium binding protein P | -0.0308517 |
| RPLP0 | ribosomal protein, large, P0 | -0.0302175 |
| RPS29 | ribosomal protein S29 | -0.0300418 |
| CCND1 | cyclin D1 | -0.0288116 |
| RPL12 | ribosomal protein L12 | -0.0287728 |
| RPL31 | ribosomal protein L31 | -0.0287661 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0286576 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0284902 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0283391 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0281827 |
| PKM | pyruvate kinase, muscle | -0.0280608 |
| GNAS | GNAS complex locus | -0.0277371 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0276967 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0274171 |
| RPS27 | ribosomal protein S27 | -0.0273418 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0271707 |
| RPS19 | ribosomal protein S19 | -0.0260822 |
| MAP7 | microtubule-associated protein 7 | -0.0259745 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0256331 |
| ATF4 | activating transcription factor 4 | -0.0252081 |
| RPL23 | ribosomal protein L23 | -0.0246693 |
| SMYD3 | SET and MYND domain containing 3 | -0.0243592 |
| RPL7 | ribosomal protein L7 | -0.0242093 |
| RPL19 | ribosomal protein L19 | -0.0240537 |
| VCL | vinculin | -0.0240394 |
| RPLP2 | ribosomal protein, large, P2 | -0.0238684 |
| RPS21 | ribosomal protein S21 | -0.0235583 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0235468 |
| TOP1 | topoisomerase (DNA) I | -0.0232651 |
| B2M | beta-2-microglobulin | -0.0232419 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0230045 |
| MORF4L2 | mortality factor 4 like 2 | -0.0228327 |
| IER3 | immediate early response 3 | -0.022773 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0227427 |
| S100A9 | S100 calcium binding protein A9 | -0.0227289 |
| LMO7 | LIM domain 7 | -0.0225673 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0224839 |
| RPL8 | ribosomal protein L8 | -0.0224727 |
| RACK1 | receptor for activated C kinase 1 | -0.0223489 |
| RPS14 | ribosomal protein S14 | -0.0222489 |
| MT1X | metallothionein 1X | -0.0218246 |
| RPL11 | ribosomal protein L11 | -0.0213984 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0209861 |
| CST3 | cystatin C | -0.0209702 |
| ANKRD37 | ankyrin repeat domain 37 | -0.020825 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.020804 |
| RPL30 | ribosomal protein L30 | -0.0206747 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0206551 |
| S100A11 | S100 calcium binding protein A11 | -0.020562 |
| RPL36A | ribosomal protein L36a | -0.0204726 |
| SCEL | sciellin | -0.0204325 |
