| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.151444 |
| TXNRD1 | thioredoxin reductase 1 | 0.074975 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0643849 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0508393 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0438715 |
| MCL1 | myeloid cell leukemia 1 | 0.0411105 |
| MKI67 | marker of proliferation Ki-67 | 0.037012 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0313284 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.031305 |
| CENPF | centromere protein F, 350/400kDa | 0.02908 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0286929 |
| RPL3 | ribosomal protein L3 | 0.0272958 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0265895 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0257448 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0255537 |
| TPM3 | tropomyosin 3 | 0.024337 |
| TPX2 | TPX2, microtubule-associated | 0.0236482 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0235947 |
| WDR43 | WD repeat domain 43 | 0.0232467 |
| HLA-B | major histocompatibility complex, class I, B | 0.0228689 |
| RPL4 | ribosomal protein L4 | 0.0226499 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0225475 |
| NUP58 | nucleoporin 58 | 0.0224604 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0220158 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0217954 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0217729 |
| USP3 | ubiquitin specific peptidase 3 | 0.0207867 |
| RTN4 | reticulon 4 | 0.0207614 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0204591 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0201296 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0199624 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0197174 |
| RPL31 | ribosomal protein L31 | 0.0196787 |
| AURKA | aurora kinase A | 0.0192805 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0189246 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0185101 |
| RRM2 | ribonucleotide reductase M2 | 0.017962 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0179367 |
| CALU | calumenin | 0.0178624 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0178022 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0177078 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0176567 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.017258 |
| KIF5B | kinesin family member 5B | 0.0170509 |
| HDGF | hepatoma-derived growth factor | 0.0169369 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0169217 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0167338 |
| CENPE | centromere protein E, 312kDa | 0.0165907 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0165685 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0165343 |
| HLA-A | major histocompatibility complex, class I, A | 0.0163804 |
| CASC3 | cancer susceptibility candidate 3 | 0.016327 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0162853 |
| ANLN | anillin, actin binding protein | 0.0161788 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0161733 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.016148 |
| CCNL1 | cyclin L1 | 0.0160811 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0159976 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0157629 |
| ENO1 | enolase 1, (alpha) | 0.0157377 |
| KIF23 | kinesin family member 23 | 0.0156503 |
| MORF4L1 | mortality factor 4 like 1 | 0.0156153 |
| MT1F | metallothionein 1F | 0.0155336 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0154957 |
| XPO1 | exportin 1 | 0.0152267 |
| FAM168A | family with sequence similarity 168, member A | 0.0151797 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0151208 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0150974 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0148374 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0148175 |
| ADAR | adenosine deaminase, RNA-specific | 0.0147309 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | 0.0146342 |
| ITGB5 | integrin, beta 5 | 0.0144486 |
| HLA-E | major histocompatibility complex, class I, E | 0.0142973 |
| RBM39 | RNA binding motif protein 39 | 0.0142329 |
| NNMT | nicotinamide N-methyltransferase | 0.0142106 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0141985 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0141806 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0139058 |
| TFG | TRK-fused gene | 0.0138542 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0138541 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0137078 |
| FLOT1 | flotillin 1 | 0.013678 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0135875 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0135707 |
| FGA | fibrinogen alpha chain | 0.0134621 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | 0.0134414 |
| TCIM | transcriptional and immune response regulator | 0.0133918 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.013372 |
| NUP153 | nucleoporin 153kDa | 0.0133383 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0133353 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0132801 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.013186 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0131809 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0131354 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0130317 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0129842 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0129784 |
| TMEM214 | transmembrane protein 214 | 0.0126209 |
| TNPO1 | transportin 1 | 0.0126129 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.196199 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.136758 |
| FTL | ferritin, light polypeptide | -0.116554 |
| TMSB10 | thymosin beta 10 | -0.106473 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105593 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0916618 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0829964 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0761621 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0755367 |
| FMNL2 | formin-like 2 | -0.0750301 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0713473 |
| DST | dystonin | -0.0610194 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0590001 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0566668 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0521104 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0491356 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0480926 |
| EGFR | epidermal growth factor receptor | -0.047612 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0458198 |
| FLNB | filamin B, beta | -0.0454347 |
| NEGR1 | neuronal growth regulator 1 | -0.045433 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0451028 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0450058 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0448142 |
| RPL23 | ribosomal protein L23 | -0.0445992 |
| MT2A | metallothionein 2A | -0.0440336 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0440292 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0437003 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0426482 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0426383 |
| AHNAK | AHNAK nucleoprotein | -0.0423114 |
| ACTG1 | actin gamma 1 | -0.0421144 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0418547 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.040974 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0407102 |
| PARD3 | par-3 family cell polarity regulator | -0.0400597 |
| S100A6 | S100 calcium binding protein A6 | -0.0395392 |
| RPL36 | ribosomal protein L36 | -0.0382922 |
| RPS21 | ribosomal protein S21 | -0.037905 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0374761 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0360815 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0360201 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0348383 |
| CMIP | c-Maf inducing protein | -0.0347495 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0344148 |
| UTRN | utrophin | -0.03441 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0342224 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0340284 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0339027 |
| IER3 | immediate early response 3 | -0.0334266 |
| RPS19 | ribosomal protein S19 | -0.0333224 |
| PFN1 | profilin 1 | -0.0324634 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0323889 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0323435 |
| EFNA5 | ephrin-A5 | -0.0323331 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0321112 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0319548 |
| TPM1 | tropomyosin 1 (alpha) | -0.0315211 |
| RPL18 | ribosomal protein L18 | -0.0312646 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.03015 |
| EHBP1 | EH domain binding protein 1 | -0.0296785 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0291688 |
| RPLP1 | ribosomal protein, large, P1 | -0.0282276 |
| SVIL | supervillin | -0.0281446 |
| KYNU | kynureninase | -0.0275867 |
| CUX1 | cut-like homeobox 1 | -0.0274218 |
| CAVIN1 | caveolae associated protein 1 | -0.0271169 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0269424 |
| INTS6 | integrator complex subunit 6 | -0.0266186 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0265926 |
| ASPH | aspartate beta-hydroxylase | -0.0261699 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0259821 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0259584 |
| RPL19 | ribosomal protein L19 | -0.0258322 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0252142 |
| RPL8 | ribosomal protein L8 | -0.0251885 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0249215 |
| GLIS3 | GLIS family zinc finger 3 | -0.0248909 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0246491 |
| GNAS | GNAS complex locus | -0.0244851 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0244217 |
| RPS27A | ribosomal protein S27a | -0.0243729 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0242184 |
| NEBL | nebulette | -0.02398 |
| MYOF | myoferlin | -0.0238289 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0233372 |
| SERF2 | small EDRK-rich factor 2 | -0.0229913 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0227884 |
| CYTH1 | cytohesin 1 | -0.0226174 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0225246 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0223472 |
| MYO1E | myosin IE | -0.0223023 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0222279 |
| CTBP2 | C-terminal binding protein 2 | -0.0221047 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0218669 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0216903 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0216844 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0207702 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0207563 |
| BICC1 | BicC family RNA binding protein 1 | -0.0207545 |
