| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | 0.131093 |
| EZR | ezrin | 0.105919 |
| FAT1 | FAT atypical cadherin 1 | 0.103309 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0994526 |
| GPC6 | glypican 6 | 0.0873066 |
| FN1 | fibronectin 1 | 0.0861578 |
| LAMC2 | laminin, gamma 2 | 0.0842727 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0841543 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0833497 |
| RORA | RAR-related orphan receptor A | 0.0799172 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0794766 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0734326 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0732411 |
| FLNB | filamin B, beta | 0.0722056 |
| CCNY | cyclin Y | 0.0718001 |
| VCL | vinculin | 0.0702993 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0694339 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0692638 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0684906 |
| RUNX1 | runt-related transcription factor 1 | 0.0676877 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0665485 |
| LAMA4 | laminin, alpha 4 | 0.0661839 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0651061 |
| POTEF | POTE ankyrin domain family, member F | 0.0621994 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0616035 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0584432 |
| HMGA2 | high mobility group AT-hook 2 | 0.0580057 |
| MT2A | metallothionein 2A | 0.0555696 |
| MSI2 | musashi RNA-binding protein 2 | 0.0554453 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0538098 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0537566 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0536926 |
| DIAPH2 | diaphanous-related formin 2 | 0.0532295 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0531972 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0530139 |
| NHSL1 | NHS-like 1 | 0.0529196 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0526287 |
| ANO6 | anoctamin 6 | 0.0520865 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0518139 |
| PKN2 | protein kinase N2 | 0.0517599 |
| ERBIN | erbb2 interacting protein | 0.0516425 |
| CAB39 | calcium binding protein 39 | 0.0510528 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0507571 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.050462 |
| MYO1D | myosin ID | 0.0499427 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0497407 |
| EGFR | epidermal growth factor receptor | 0.0496382 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0493075 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0484727 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0482928 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0479314 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0475443 |
| MCL1 | myeloid cell leukemia 1 | 0.0475348 |
| FAM193A | family with sequence similarity 193, member A | 0.0474469 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0474161 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0470925 |
| TMEM165 | transmembrane protein 165 | 0.0460574 |
| ATP11A | ATPase, class VI, type 11A | 0.0455738 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0455143 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0454984 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0453509 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0448152 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0446282 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0443327 |
| C1D | C1D nuclear receptor corepressor | 0.0436143 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0435527 |
| TCF12 | transcription factor 12 | 0.0433356 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0429965 |
| ZNF292 | zinc finger protein 292 | 0.0424568 |
| JUP | junction plakoglobin | 0.0420569 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0416907 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.041668 |
| RPL37 | ribosomal protein L37 | 0.0410938 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0410369 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0409008 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0406875 |
| ETF1 | eukaryotic translation termination factor 1 | 0.0404277 |
| SLMAP | sarcolemma associated protein | 0.0401868 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0399663 |
| RBM6 | RNA binding motif protein 6 | 0.0398225 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0397477 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0394158 |
| PHF3 | PHD finger protein 3 | 0.0393423 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0393394 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.039124 |
| ACTN4 | actinin, alpha 4 | 0.038842 |
| RAD51B | RAD51 paralog B | 0.0381548 |
| SP3 | Sp3 transcription factor | 0.0377544 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0374407 |
| SMAD3 | SMAD family member 3 | 0.0373233 |
| SBF2 | SET binding factor 2 | 0.0369108 |
| DTNA | dystrobrevin, alpha | 0.0368444 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0367867 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0358016 |
| TPD52 | tumor protein D52 | 0.035523 |
| FNIP1 | folliculin interacting protein 1 | 0.0344257 |
| USP3 | ubiquitin specific peptidase 3 | 0.033784 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0337396 |
| HLA-B | major histocompatibility complex, class I, B | 0.0335208 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0334264 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.148691 |
| FTL | ferritin, light polypeptide | -0.135341 |
| GRB10 | growth factor receptor-bound protein 10 | -0.127587 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.12242 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.118833 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.117773 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.115826 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.108795 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0965011 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0929092 |
| TMSB10 | thymosin beta 10 | -0.0916886 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.086529 |
| SRPK2 | SRSF protein kinase 2 | -0.0864874 |
| RPS19 | ribosomal protein S19 | -0.0832422 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0797699 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0792386 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.079017 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0778452 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0752637 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0740008 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0731493 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0695514 |
| NEBL | nebulette | -0.068639 |
| TXNIP | thioredoxin interacting protein | -0.0677956 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0656637 |
| UBC | ubiquitin C | -0.0638086 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0621358 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.061308 |
| NPTN | neuroplastin | -0.0610927 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0605641 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0599941 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0588025 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0580924 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0579837 |
| OGA | O-GlcNAcase | -0.0570847 |
| USP53 | ubiquitin specific peptidase 53 | -0.0565433 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0565232 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0545494 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0544491 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0544056 |
| RBM39 | RNA binding motif protein 39 | -0.0541554 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.05412 |
| S100A10 | S100 calcium binding protein A10 | -0.0523795 |
| TBCA | tubulin folding cofactor A | -0.052179 |
| PDE10A | phosphodiesterase 10A | -0.0519947 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0505659 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0503127 |
| RIGI | RNA sensor RIG-I | -0.0492975 |
| ZNF638 | zinc finger protein 638 | -0.0492681 |
| TMEM41B | transmembrane protein 41B | -0.0491391 |
| KIAA1217 | KIAA1217 | -0.0489679 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -0.0485214 |
| AFAP1 | actin filament associated protein 1 | -0.0484723 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.04836 |
| PHF21A | PHD finger protein 21A | -0.0482652 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0473285 |
| CANX | calnexin | -0.0471892 |
| PRELID2 | PRELI domain containing 2 | -0.0469763 |
| GOLGB1 | golgin B1 | -0.0461543 |
| ATOSA | atos homolog A | -0.0461315 |
| AHNAK | AHNAK nucleoprotein | -0.0460825 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0459053 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0443 |
| SEC24D | SEC24 family member D | -0.0442078 |
| FNBP4 | formin binding protein 4 | -0.0441594 |
| S100A6 | S100 calcium binding protein A6 | -0.0434636 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0434586 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0434121 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0430152 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0428874 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0425835 |
| CD2AP | CD2-associated protein | -0.0425395 |
| ACVR1 | activin A receptor, type I | -0.0422419 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0417303 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.041709 |
| NEK7 | NIMA-related kinase 7 | -0.0410417 |
| LAMB1 | laminin, beta 1 | -0.0406369 |
| RPS13 | ribosomal protein S13 | -0.0402027 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0401919 |
| RUFY1 | RUN and FYVE domain containing 1 | -0.0401808 |
| DICER1 | dicer 1, ribonuclease type III | -0.0401323 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0389873 |
| CDC42 | cell division cycle 42 | -0.0388927 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0385535 |
| H3-3B | H3.3 histone B | -0.0382389 |
| AFF1 | AF4/FMR2 family, member 1 | -0.038038 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0378576 |
| PTMA | prothymosin, alpha | -0.0378187 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0376993 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0376309 |
| KIAA1671 | KIAA1671 | -0.0374583 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0374206 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0373354 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0367068 |
| ABHD17C | abhydrolase domain containing 17C | -0.0362276 |
| DENND4C | DENN/MADD domain containing 4C | -0.0362015 |
| TANK | TRAF family member-associated NFKB activator | -0.0360987 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.036035 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.035672 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0354685 |
