| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.1874 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.136658 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.132355 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.105604 |
| RAD51B | RAD51 paralog B | 0.092799 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0761453 |
| ENO1 | enolase 1, (alpha) | 0.0721697 |
| TPM3 | tropomyosin 3 | 0.0707195 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0643983 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0624043 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0615506 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0584487 |
| TXNRD1 | thioredoxin reductase 1 | 0.0569373 |
| PGK1 | phosphoglycerate kinase 1 | 0.0566097 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0561283 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0557541 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0544894 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0537448 |
| BBX | bobby sox homolog (Drosophila) | 0.0487068 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0484892 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0481082 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0462712 |
| TLN1 | talin 1 | 0.046086 |
| MCL1 | myeloid cell leukemia 1 | 0.0445953 |
| PCBP2 | poly(rC) binding protein 2 | 0.0439895 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0439308 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0426221 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0418955 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0407381 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0401122 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0397819 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0390569 |
| BRD2 | bromodomain containing 2 | 0.0389045 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0383955 |
| PHIP | pleckstrin homology domain interacting protein | 0.0383154 |
| RBM39 | RNA binding motif protein 39 | 0.0382248 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0381664 |
| OGA | O-GlcNAcase | 0.0378516 |
| PRRC2A | proline-rich coiled-coil 2A | 0.037679 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.037538 |
| RTN4 | reticulon 4 | 0.0373308 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0364588 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0359643 |
| NOTCH2 | notch 2 | 0.0359061 |
| PRELID2 | PRELI domain containing 2 | 0.035367 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0348917 |
| XPO1 | exportin 1 | 0.0347583 |
| RPL3 | ribosomal protein L3 | 0.0342641 |
| ADAR | adenosine deaminase, RNA-specific | 0.0342445 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0342113 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0339418 |
| GOLGA4 | golgin A4 | 0.0338819 |
| POTEF | POTE ankyrin domain family, member F | 0.0334702 |
| COPA | coatomer protein complex, subunit alpha | 0.0334653 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0332109 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0331361 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0326243 |
| NUP58 | nucleoporin 58 | 0.0325791 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0325661 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0325176 |
| RLF | rearranged L-myc fusion | 0.0324119 |
| TMEM165 | transmembrane protein 165 | 0.0320783 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.032042 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0320418 |
| CEP192 | centrosomal protein 192kDa | 0.0314837 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0314574 |
| SBF2 | SET binding factor 2 | 0.0313988 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0313844 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0312935 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0310344 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0309421 |
| PKM | pyruvate kinase, muscle | 0.0308826 |
| LDHA | lactate dehydrogenase A | 0.0306752 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0303972 |
| ZNF638 | zinc finger protein 638 | 0.0303035 |
| PCM1 | pericentriolar material 1 | 0.0298275 |
| MKI67 | marker of proliferation Ki-67 | 0.0298097 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0294544 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0292431 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0291637 |
| ANO6 | anoctamin 6 | 0.0290468 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0290443 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0289494 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0288052 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0287889 |
| ZNF292 | zinc finger protein 292 | 0.0287589 |
| RSF1 | remodeling and spacing factor 1 | 0.0287282 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0283084 |
| ATXN2 | ataxin 2 | 0.028202 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0280011 |
| RBM33 | RNA binding motif protein 33 | 0.027968 |
| RLIM | ring finger protein, LIM domain interacting | 0.0279276 |
| MSH6 | mutS homolog 6 | 0.0279173 |
| PRPF8 | pre-mRNA processing factor 8 | 0.027867 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0278123 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.027797 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0277237 |
| PCNX1 | pecanex 1 | 0.0276699 |
| KIF5B | kinesin family member 5B | 0.0276532 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0276309 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.143311 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0703231 |
| OSMR | oncostatin M receptor | -0.0547001 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0539806 |
| TMSB10 | thymosin beta 10 | -0.0482404 |
| HMGA2 | high mobility group AT-hook 2 | -0.0430231 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0413053 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0406608 |
| RPL35A | ribosomal protein L35a | -0.0403198 |
| VCL | vinculin | -0.0391337 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0350735 |
| RPS3 | ribosomal protein S3 | -0.0350613 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0342175 |
| CDK17 | cyclin-dependent kinase 17 | -0.0332732 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0331431 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0327789 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0324313 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0321817 |
| RPS8 | ribosomal protein S8 | -0.031666 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0314481 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0298399 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0291621 |
| MT2A | metallothionein 2A | -0.0290237 |
| RPL23 | ribosomal protein L23 | -0.0283631 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0281491 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.027651 |
| IER3 | immediate early response 3 | -0.0272141 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0267311 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0255207 |
| RPL12 | ribosomal protein L12 | -0.0254846 |
| INTS6 | integrator complex subunit 6 | -0.0252765 |
| RPS15 | ribosomal protein S15 | -0.0250083 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0246436 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0243522 |
| PDLIM5 | PDZ and LIM domain 5 | -0.024124 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0240294 |
| RPS24 | ribosomal protein S24 | -0.0239127 |
| TRIM56 | tripartite motif containing 56 | -0.0234814 |
| RPL38 | ribosomal protein L38 | -0.0231538 |
| RPL26 | ribosomal protein L26 | -0.0231466 |
| PDE10A | phosphodiesterase 10A | -0.0230851 |
| HLA-B | major histocompatibility complex, class I, B | -0.022783 |
| RPL36A | ribosomal protein L36a | -0.0227203 |
| RPS29 | ribosomal protein S29 | -0.0226643 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0224672 |
| PLSCR1 | phospholipid scramblase 1 | -0.0223385 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0218107 |
| RIGI | RNA sensor RIG-I | -0.021752 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0216038 |
| AEBP2 | AE binding protein 2 | -0.0214943 |
| RPS27 | ribosomal protein S27 | -0.0213977 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.021383 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0209946 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0206967 |
| RPL34 | ribosomal protein L34 | -0.02064 |
| S100A11 | S100 calcium binding protein A11 | -0.0205653 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0205028 |
| AFF3 | AF4/FMR2 family, member 3 | -0.020116 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0194299 |
| RPL31 | ribosomal protein L31 | -0.0194176 |
| RPL32 | ribosomal protein L32 | -0.019239 |
| RPS19 | ribosomal protein S19 | -0.0187839 |
| RPS27A | ribosomal protein S27a | -0.018491 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0182368 |
| STC1 | stanniocalcin 1 | -0.0182094 |
| DHFR | dihydrofolate reductase | -0.0180702 |
| RPS21 | ribosomal protein S21 | -0.0179222 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0178992 |
| RPLP1 | ribosomal protein, large, P1 | -0.017687 |
| RPLP2 | ribosomal protein, large, P2 | -0.0175094 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0172157 |
| RPS23 | ribosomal protein S23 | -0.0171831 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0171648 |
| PHF14 | PHD finger protein 14 | -0.0169968 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0168795 |
| SETX | senataxin | -0.016864 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0167276 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0166683 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.016569 |
| PTMA | prothymosin, alpha | -0.0163885 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0163344 |
| RPL6 | ribosomal protein L6 | -0.0162545 |
| RPS25 | ribosomal protein S25 | -0.0162349 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0161422 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0161169 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0160507 |
| TFCP2 | transcription factor CP2 | -0.0160076 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0157801 |
| RPL9 | ribosomal protein L9 | -0.0157677 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0156706 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0156043 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.015563 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0155295 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0152283 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | -0.0150737 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0149231 |
| RYR3 | ryanodine receptor 3 | -0.0147654 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0146174 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0145388 |
| CAVIN1 | caveolae associated protein 1 | -0.014485 |
